A5007870613- Insect Resistance and Genetics
- Invertebrate Immune Response Mechanisms
- Glycosylation and Glycoproteins Research
- Genetic Mapping and Diversity in Plants and Animals
- Microbial Metabolic Engineering and Bioproduction
- Insect and Pesticide Research
- Studies on Chitinases and Chitosanases
- Insect-Plant Interactions and Control
- Insect behavior and control techniques
- Insect symbiosis and bacterial influences
- Neurobiology and Insect Physiology Research
- Plant Virus Research Studies
- Forest Insect Ecology and Management
- Transgenic Plants and Applications
- Toxin Mechanisms and Immunotoxins
- Fungal and yeast genetics research
- CRISPR and Genetic Engineering
- Insect and Arachnid Ecology and Behavior
- Photosynthetic Processes and Mechanisms
- Carbohydrate Chemistry and Synthesis
- Plant Molecular Biology Research
- Galectins and Cancer Biology
- Phytoplasmas and Hemiptera pathogens
- Microtubule and mitosis dynamics
- Genomics and Phylogenetic Studies
Ghent University
2014-2024
Southwest University
2020
VIB-UGent Center for Medical Biotechnology
2012
Vlaams Instituut voor Biotechnologie
2004-2009
Centre National pour la Recherche Scientifique et Technique (CNRST)
2007
Laboratoire de Biogenèse Membranaire
2007
Université de Bordeaux
2007
Nord University
1953
University of Palestine
1953
Rutland Regional Medical Center
1953
Pichia pastoris has been a workhorse of protein production for decades. De Schutter et al. present its genomic sequence, which will allow development improved strains. The methylotrophic yeast is widely used the proteins and as model organism studying peroxisomal biogenesis methanol assimilation. P. strains capable human-type N-glycosylation are now available, increases utility this biopharmaceutical production. Despite biotechnological importance, relatively few genetic tools or engineered...
Abstract Upon the incidence of DNA stress, ataxia telangiectasia–mutated (ATM) and Rad3-related (ATR) signaling kinases activate a transient cell cycle arrest that allows cells to repair before proceeding into mitosis. Although ATM-ATR pathway is highly conserved over species, mechanisms by which plant stop their in response loss genome integrity are unclear. We demonstrate regulatory WEE1 kinase gene Arabidopsis thaliana transcriptionally activated upon cessation replication or damage an...
Abstract While the overuse of classical chemical pesticides has had a detrimental impact on environment and human health, discovery RNA interference (RNAi) offered opportunity to develop new sustainable approaches for pest management. RNAi is naturally occurring regulation defense mechanism that can be exploited effectively protect crops by silencing key genes affecting growth, development, behavior or fecundity pests. However, as with all technologies, there range potential risks challenges...
Abstract Entry into mitosis is universally controlled by cyclin-dependent kinases (CDKs). A key regulatory event in metazoans and fission yeast CDK activation the removal of inhibitory phosphate groups ATP binding pocket catalyzed Cdc25 phosphatases. In contrast with other multicellular organisms, we show here that flowering plant Arabidopsis thaliana, cell cycle control does not depend on sudden changes phosphorylation pattern PSTAIRE-containing Cdk1 homolog CDKA;1. Consistently, found...
The first genome sequences of the important yeast protein production host Pichia pastoris have been released into public domain this spring. In order to provide scientific community easy and versatile access sequence, two web-sites installed as a resource for genomic gene information P. pastoris: A GBrowse based browser was set up at http://www.pichiagenome.org portal with annotation browsing functionality http://bioinformatics.psb.ugent.be/webtools/bogas . Both websites are offering on...
Ticks are important ectoparasites and vectors of numerous human animal pathogens. secrete saliva that contains various bioactive materials to evade the host defense system, often facilitates pathogen transmission. In addition, Lone star tick is thought be sensitizer in red meat allergy characterized by an allergic reaction glycan moieties carrying terminal galactose-alpha-1,3-galactose (aGal). To assess N-glycome Amblyomma americanum, we examined N-glycan structures male female salivary...
Lectins are present throughout the plant kingdom and reported to be involved in diverse biological processes. In this study, we provide a comparative analysis of lectin families from model species phylogenetic framework. The focuses on different domains identified five representative core angiosperm genomes (Arabidopsis thaliana, Glycine max, Cucumis sativus, Oryza sativa ssp. japonica indica). were screened for genes encoding using combination Basic Local Alignment Search Tool (BLAST),...
Spirodiclofen is an acaricide that targets lipid biosynthesis by inhibiting acetyl-coenzyme A carboxylase. resistance in spider mites has been previously documented and was associated with overexpression of CYP392E10, a cytochrome P450 mono-oxygenase metabolizes spirodiclofen. However, additional mechanisms have suggested several studies carboxyl/choline esterase gene, CCE04, shown to be overexpressed two genetically different strains, SR-VP SR-TK, both exhibiting high spirodiclofen...
Summary In plant cells, overexpression of critical genes can be hampered by deleterious effects on development that results in a counterselection transgenic cells harboring the gene interest. Inducible expression systems have been reported, but many them show unwanted leaky expression. To circumvent this potential problem, novel inducible system was developed based two previously characterized systems: CRE‐ loxP site‐specific recombination bacteriophage P1 and subcellular targeting proteins...
RNA interference (RNAi) has shown substantial promise as a sustainable pest management solution. However, the efficacy of RNAi-based insecticides heavily relies on advanced nanocarrier-mediated delivery systems. In this study, we modified raw graphene oxide into positively charged nanocarriers (GONs) tailored to bind with double-stranded (dsRNA). The resulting GONs@dsRNA complexes demonstrated small particle size (106 nm) and maintained stability under various conditions, including insect...
Lectins, defined as 'Proteins that can recognize and bind specific carbohydrate structures', are widespread among all kingdoms of life play an important role in various biological processes the cell. Most plant lectins involved stress signaling and/or defense. The family Euonymus-related (EULs) represents a group stress-related composed one or two EUL domains. latter protein domain is unique it ubiquitous land plants, suggesting for these proteins.Despite availability multiple completely...
The oriental fruit fly, Bactrocera dorsalis (Hendel) has been considered to be one of the most important agricultural pest around world. As a holometabolous insect, larvae must go through metamorphosis process with dramatic morphological and structural changes complete their development. To better understand molecular mechanisms these changes, RNA-seq B. from wandering stage (WS), late (LWS) white puparium (WPS) were performed. In total, 11,721 transcripts obtained, out which 1914 genes (578...
Insect Capability neuropeptides (CAP2b/CAPA-PKs) play a critical role in modulating different physiologies and behavior insects. In previous proof-of-concept study, the CAP2b analogues 1895 (2Abf-Suc-FGPRLamide) 2129 (2Abf-Suc-ATPRIamide) were reported to reduce aphid fitness when administered by injection. current insecticidal efficacy of on peach potato Myzus persicae was analyzed topical application, simulating spray application scenario field. Additionally, selectivity tested evaluated...