A5022573719- Disaster Response and Management
- Colorectal Cancer Screening and Detection
- Medical Imaging Techniques and Applications
- Nutritional Studies and Diet
- Gallbladder and Bile Duct Disorders
- Genetic factors in colorectal cancer
- Disaster Management and Resilience
- Radiomics and Machine Learning in Medical Imaging
- Obesity, Physical Activity, Diet
- Advanced X-ray and CT Imaging
- Cardiac Imaging and Diagnostics
- Adipokines, Inflammation, and Metabolic Diseases
- Coffee research and impacts
- Cardiovascular Disease and Adiposity
- Oral microbiology and periodontitis research
- Palliative Care and End-of-Life Issues
- Alcohol Consumption and Health Effects
- Advanced MRI Techniques and Applications
- Adipose Tissue and Metabolism
- Tea Polyphenols and Effects
- Liver Disease Diagnosis and Treatment
- Metabolism, Diabetes, and Cancer
- Thermochemical Biomass Conversion Processes
- Health, psychology, and well-being
- Pulmonary Hypertension Research and Treatments
SCREEN (Japan)
2024
Chiba University Hospital
2010-2024
Saga University
2014-2024
Kanazawa University
2023
Kanazawa University Hospital
2023
Chiba University
2023
Toyonaka Municipal Hospital
2021
Japan Fisheries Research and Education Agency
1993-2018
Kilis 7 Aralık University
2013
Nagoya University
2000-2011
Background: Most diseases are thought to arise from interactions between environmental factors and the host genotype. To detect gene–environment in development of lifestyle-related diseases, especially cancer, Japan Multi-institutional Collaborative Cohort (J-MICC) Study was launched 2005.Methods: We initiated a cross-sectional study examine associations genotypes with lifestyle clinical factors, as assessed by questionnaires medical examinations. The 4519 subjects were selected among...
Although quantitative analysis using standardized uptake value (SUV) becomes realistic in clinical single-photon emission computed tomography/computed tomography (SPECT/CT) imaging, reconstruction parameter settings can deliver different results among SPECT/CT systems. This study aims to propose a use of the digital reference object (DRO), which is National Electrical Manufacturers Association (NEMA) phantom-like developed by Quantitative Imaging Biomarker Alliance (QIBA)...
Background: Dietary pattern may influence the risks of cardiovascular disease, atherosclerosis, type 2 diabetes, and metabolic syndrome through its effects on inflammation. We evaluated association between dietary serum high-sensitivity C-reactive protein (hs-CRP) in a Japanese population.Methods: In this cross-sectional analysis, we used baseline data from 3905 men 5640 women (age 40–69 years) who participated population-based cohort study November 2005 December 2007. Participants with...
Abstract Background L-type amino acid transporter 1 (LAT1) is overexpressed in various cancers; therefore, radiohalogen-labeled derivatives targeting LAT1 have emerged as promising candidates for cancer radiotheranostics. However, 211 At-labeled exhibit instability against deastatination vivo, making it challenging to use At radiotherapy. In this study, with high dehalogenation stability were developed. Results We designed and synthesized new ([ At]At-NpGT, [ 125 I]I-NpGT, 18 F]F-NpGT) which...
The relation between obesity and adenomatous polyps of the sigmoid colon was investigated in male self‐defense officials who received a retirement health examination at three hospitals Self‐Defense Forces Japan January 1991 December 1992. Body mass index (BMI) waist‐hip circumference ratio (WHR) were used as indices obesity. A total 228 adenoma cases 1484 controls with normal sigmoidoscopy identified 2228 men: having small adenomas (<5 mm diameter) those large (5 or greater) numbered 115...
Animal experiments have shown a hypocholesterolemic effect of green tea extracts. Only few epidemiological studies addressed the relation between consumption and serum total cholesterol (TC) low density lipoprotein (LDL-C). This paper examined to lipids lipoproteins in 2,062 male self-defense officials Japan, aged 49-55 years, who received preretirement health examination at three hospitals Self-Defense Forces 1991-1992. A self-administered questionnaire queried limited number other dietary...
The relation of dietary factors to the risk adenomas sigmoid colon was examined in men receiving a retirement health examination at Self‐Defense Forces Fukuoka Hospital between October 1986 and 1990. A total 187 adenoma cases 1557 controls with normal colonoscopy were identified series. Cases further classified into small‐adenoma (<5 mm, n=78) large‐adenoma (≥5 n=67) groups. consumptions selected foods beverages ascertained before by means self‐administered questionnaire. After adjustment...
The relation of coffee drinking and other behavioral factors to serum gammaglutamyltransferase (GGT) was examined in 2,494 male self-defense officials aged 48–56 years, who received a retirement health examination at the Self-Defense Forces Fukuoka Hospital between October 1986 December 1990. Coffee, but not green tea, consumption inversely related GGT independently body mass index, alcohol use, smoking. All latter variables were also positively associated with GGT. Lower levels more evident...
AbstractBackground: Risk factors for gallstones are not fully understood, especially in men. Obesity and other risk gallstone disease were investigated Japanese men based on gallbladder ultrasonography. Methods: Forty-one with gallstones, 31 postcholecystectomy state, 2044 a normal identified among 2228 aged 49-55 years who received retirement health examination at three hospitals of the Japan Self-Defense Forces between 1991 1992. Glucose tolerance was determined 75-g oral glucose test....
The relationship of adenomatous polyps the sigmoid colon with cigarette smoking and alcohol use was investigated in male self-defense officials Japan. In comparison between 116 cases 930 controls, total ethanol intake not at all associated risk polyps, but strongly related to polyps. After adjustment for intake, body mass index rank, odds ratios (and 95% confidence interval) categories 0, 1-399, 400-799, 800 or more cigarette-years were 1.0 (referent), 2.3 (1.1-4.6), 2.9 (1.5-5.4) 3.2...
Background: Little is known of factors determining infection with Helicobacter pylori. Methods: In a cross-sectional study 566 men aged 50–55 years, who received preretirement health examination at the Self Defense Forces Fukuoka Hospital between January 1993 and December 1994, we examined association smoking, alcohol use, dietary habits H. pylori infection. Results: The overall seropositivity as determined IgG antibody was 79.3% (449 566). rank inversely associated (trend, P = 0.048)....
The drinking habits of 86 men with adenomatous polyps the sigmoid colon were compared to those 1184 normal colonoscopy among middle-aged male self-defence officials. After adjustment for rank, smoking history and rice consumption, total ethanol intake was positively associated risk polyps. odds ratio (OR) 2.4 (95% confidence interval (Cl) 1.0–5.5) consuming at least 60 ml per day. Among five alcoholic beverages (shochu, beer, sake, whiskey wine), both sake beer showed a dose-response...
Background: Although many studies have examined factors that influence the response to postal questionnaires, few addressed baseline recruitment for cohort involving genetic analyses. The aim of this study was describe method used a survey, Japan Multi-institutional Collaborative Cohort Study (J-MICC Study), in Saga Prefecture, and examine might participants such studies.Methods: J-MICC is an ongoing population-based prospective environmental interactions associated with lifestyle-related...
To evaluate the pertinent cutoffs of waist circumference (WC) and discriminatory performance other anthropometric indices to detect clustering cardiovascular risk factors for metabolic syndrome (MetS) in Japan, where current WC MetS (85 cm men 90 women) remain controversial. We analyzed baseline data from 844 subjects (330 514 aged 40–69 years who participated a cohort study Saga city, between November 2005 December 2007. Receiver operating characteristic (ROC) analyses were performed find...
Background Folate intake may be related to decreased risk of colorectal cancer and adenomas. Methylenetetrahydrofolate reductase (MTHFR) is a key regulatory enzyme in folate metabolism. We examined the relation between plasma status adenomas with reference effect modification by genetic polymorphism (C677T) MTHFR.
We conducted a case‐control study, using 429 cases with histologically confirmed sigmoid adenoma, 75 rectal and 3101 controls showing normal colonoscopy at least up to 60 cm from the anus. The subjects were male Self‐Defense Forces personnel aged 48–56 who received retirement health examination including routine sigmoid‐ or colonoscopy. Lifestyle characteristics ascertained by self‐administered questionnaire. Smoking in recent past (ġ 10 years preceding colonoscopy) smoking remote (>10...