A5081875091- Landslides and related hazards
- Advanced MRI Techniques and Applications
- Blood Pressure and Hypertension Studies
- Dam Engineering and Safety
- Cerebrovascular and Carotid Artery Diseases
- Granular flow and fluidized beds
- Soil and Unsaturated Flow
- Cardiovascular Health and Disease Prevention
- Acute Ischemic Stroke Management
- Grouting, Rheology, and Soil Mechanics
- Geotechnical Engineering and Underground Structures
- Neurological disorders and treatments
- Geotechnical Engineering and Analysis
- Cerebral Venous Sinus Thrombosis
- Intracranial Aneurysms: Treatment and Complications
- Geotechnical and Geomechanical Engineering
- Cardiovascular and Diving-Related Complications
- Genetic Neurodegenerative Diseases
- Multiple Sclerosis Research Studies
- Hydrology and Sediment Transport Processes
- Neurological and metabolic disorders
- Cardiac Valve Diseases and Treatments
- Diet and metabolism studies
- Infective Endocarditis Diagnosis and Management
- Parkinson's Disease Mechanisms and Treatments
Vita-Salute San Raffaele University
2022-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2019-2025
Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele
2022-2025
Ospedale Valduce
2024
IRCCS Ospedale San Raffaele
2023-2024
Agostino Gemelli University Polyclinic
2019-2023
Alessandro Manzoni Hospital
2023
University of Rome Tor Vergata
2008-2020
Università Cattolica del Sacro Cuore
1986-2020
University of Campania "Luigi Vanvitelli"
2019-2020
Eleven of 31 clinical centers participating in the Italian Acute Stroke Study--Hemodilution carried out a preliminary study on effectiveness ganglioside GM1 acute stroke; 502 patients were randomized to (GM1, n = 121), plus hemodilution (GM1 + H, 128), placebo (P, 130), or (P 123) groups less than equal 12 hours after onset hemispheric cerebral infarct. The treated for 15 days and evaluated Days 21 120 stroke. Intention-to-treat analysis failed show any differences neurologic deficit,...
We assessed 195 subjects with histories of adverse reactions to aminopenicillins, using 1) skin tests penicilloyl polylysine (PPL), minor determinant mixture (MDM), benzylpenicillin (PG), amoxicillin, and ampicillin (read after 20 min 48 h); 2) patch PG, ampicillin; 3) RAST for penicilloyls G V. Oral challenges ampicillin, penicillin V were administered 34/60 patients reporting maculopapular reactions. Immediate hypersensitivity (IH), in most cases both was diagnosed (based on tests, RAST,...
Journal Article Prevention of postoperative recurrence with azathioprine or infliximab in patients Crohn's disease: An open-label pilot study Get access Alessandro Armuzzi, Armuzzi aIBD Unit, Complesso Integrato Columbus, Catholic University, Rome, Italy ⁎Corresponding author at: IBD Via G. Moscati 31-33, 00168 Italy. alearmuzzi@yahoo.com Tel.: + 39 063503310; fax: 063054641. Search for other works by this on: Oxford Academic PubMed Google Scholar Carla Felice, Felice Alfredo Papa, Papa...
To assess the impact on stroke outcome of statin use in acute phase after IV thrombolysis.Multicenter study prospectively collected data 2,072 patients treated with thrombolysis. Outcome measures efficacy were neurologic improvement (NIH Stroke Scale [NIHSS] ≤ 4 points from baseline or NIHSS = 0) and major (NIHSS 8 at 7 days favorable (modified Rankin [mRS] 2) excellent functional (mRS 1) 3 months. safety 7-day deterioration ≥ death), symptomatic intracerebral hemorrhage type 2 death within...
The primary objective of the SKIN-COBRA (Consortium for Brachytherapy data Analysis) ontology is to define a specific terminological system standardize collection non-melanoma skin cancer patients treated with brachytherapy (BT, interventional radiotherapy). Through ontological characterization information, it possible find, isolate, organize, and integrate its meaning.SKIN-COBRA standardized consortium BT, including 8 centers. Its was firstly defined by multicentric multidisciplinary...
Objective This study applied a synovitis score obtained during routine care from ultrasound (US)–guided biopsies of synovial tissue (ST) in patients with rheumatoid arthritis (RA) and other inflammatory noninflammatory joint diseases to identify pretreatment biomarkers associated disease characteristics, integrate the findings into multiparameter nomogram for use baseline prediction diagnosis treatment response treatment‐naive patients. Methods The enrolled total 1,015 various autoimmune...
Abstract Proton magnetic resonance spectroscopy ( 1 H‐MRS), localized to the lentiform nucleus, was carried out in 12 patients with idiopathic Parkinson's disease (IPD), seven multiple‐system atrophy (MSA), progressive supranuclear palsy (PSP), and 10 healthy age matched controls. The study assessed level of N‐acetylaspartate (NAA), creatine–phosphocreatine (Cr), choline (Cho) putamen globus pallidus these patients. NAA/Cho NAA/Cr ratios were significantly reduced MSA PSP No significant...
Proton magnetic resonance spectroscopy (1H-MRS) localised to the lentiform nucleus, was carried out in eight patients with idiopathic Parkinson's disease and five progressive supranuclear palsy. The aim of study assess concentration N-acetyl-aspartate (NAA), creatine phosphocreatine (Cr), choline containing compounds (Cho) putamen globus pallidus these patients.Peak ratios obtained from were compared those nine healthy age matched controls.NAA/Cho NAA/Cr reduced significantly palsy.These...
Abstract Overweight/obesity influence disease burden and clinical outcome of Rheumatoid Arthritis (RA). The impact overweight/obesity on synovial tissue (ST) inflammation is largely unknown. Here, we investigated the histological transcriptional signature ST obtained from RA in different phases (disease onset, failure to first-line conventional DMARDs sustained ultrasound remission) finding that overweight/obese naive showed higher likelihood follicular synovitis, IHC scores for sublining...
<b><i>Article abstract</i></b> In a case–control study, the authors found that arterial hypertension occurred more frequently among 115 patients with primary hemifacial spasm than neurologic controls matched for age (±5 years), sex, and referral center. The association was not confounded by education level, smoking history, diabetes, or other diseases (adjusted OR 2.64; 95% CI 1.3 to 5.33, <i>p</i> = 0.007). Hypertension significantly associated outcome in left-sided group (OR 4.0; 1.4...
Venous echo-color-Doppler (ECD) showed that chronic cerebrospinal venous insufficiency (CCSVI) syndrome is related to multiple sclerosis (MS). Study aims were assess interobserver variability in ultrasound evaluation of MS patients and relate echo-markers clinical symptoms the disability degree. 277 (117 men, mean age 43.05+10.04 years) admitted Neurology Department Bari University General Hospital, underwent clinical, Expanded Disability Status Scale (EDSS) evaluation, a cerebro-venous...
Several empirical relationships allowing a preliminary estimate of debris flow runout distances have been proposed to correlate the length volume sliding granular mass, delimit potentially hazardous areas, and design safeguarding measures. To overcome their large variability define fields applicability, an energy-based model, predicting mobility, is developed. The power balance mass along two planar surfaces written by taking into account slopes surfaces, assigned interstitial pressure,...
Differential diagnosis among psoriatic arthritis (PsA) and seronegative rheumatoid (Abneg RA) can be challenging particularly in the clinical setting of peripheral phenotype autoantibodies seronegativity. The aim study was to identify synovial tissue (ST) biomarkers differentially expressed PsA Abneg RA test their predictive value therapeutic response.Thirty-four patients [12 DMARD naive 22 non-responder methotrexate (MTX-IR)] with joint involvement 55 (27 28 MTX-IR) underwent US-guided ST...
High blood pressure (BP) poses a major risk for cognitive decline. Aim of the study was to highlight relationship between assessment scores and an effective therapeutic BP control.By medical visit ambulatory monitoring (ABPM), we studied 302 treated hypertensives, subdivided according office/daytime values into 120 with good (GC) 98 poor (PC) control, 40 "white coat hypertension" (WCH) 44 "masked-hypertension" phenomenon (MH). Patients underwent neuropsychological evaluate global at Mini...
Objective . To compare the efficacy of two sedating antidepressants, trazodone and mirtazapine, for treatment chronic insomnia. Design Retrospective cross-sectional study. Patients received or mirtazapine at least three months dosage that was effective in titration period. Material Methods 150 patients with insomnia, referred to Sleep Disorder Center Bari, diagnosed as insomniacs according ICSD-3 diagnostic criteria, without dysthymic disorder DSM V treated were retrospectively...
Cancer treatment-related adverse events (AEs) are sometimes associated with outcomes for cancer patients, especially the newest therapies such as target therapy and immunotherapy. A few years ago, first-line hormone-receptor-positive metastatic breast (mBC) patients has been deeply changed by introduction of cyclin-dependent kinase (CDK) 4/6 inhibitors, now, we improving our knowledge about their AEs significance in clinical practice. Here, report experience two cases vitiligo-like lesions...