- Head and Neck Surgical Oncology
- Sinusitis and nasal conditions
- Orthopedic Infections and Treatments
- Infectious Diseases and Tuberculosis
- Osteomyelitis and Bone Disorders Research
- Pituitary Gland Disorders and Treatments
- COVID-19 epidemiological studies
- Vaccine Coverage and Hesitancy
- Diabetes Management and Education
- Meningioma and schwannoma management
- Advanced Chemical Sensor Technologies
- COVID-19 Pandemic Impacts
- Respiratory and Cough-Related Research
- Cardiovascular Health and Risk Factors
- Inflammatory mediators and NSAID effects
- Bone Tumor Diagnosis and Treatments
- Biochemical Analysis and Sensing Techniques
- Clinical practice guidelines implementation
- Asthma and respiratory diseases
- Cardiac, Anesthesia and Surgical Outcomes
- Atrial Fibrillation Management and Outcomes
- Mobile Health and mHealth Applications
- Vestibular and auditory disorders
- Adrenal Hormones and Disorders
- Marine Sponges and Natural Products
University of Pennsylvania
2020-2025
Brigham Young University
2024-2025
University of Pennsylvania Health System
2022-2024
Oregon Health & Science University
2023-2024
Hospital of the University of Pennsylvania
2022
Sports Science Institute of South Africa
2021
University of the Witwatersrand
2021
Aarhus University
2020
Device-related infections (DRIs) from bacterial/fungal biofilms that form on surfaces are a major cause of death in first-world countries. DRIs and the increasing prevalence antibiotic resistant strains require development new antimicrobials for improved antimicrobial prophylaxis. New prophylaxis practices necessitate novel agents to combat broad spectrum both fungi bacteria, be less toxic patients, locally administrable prevent perturbations patient's microbiome. A class we have previously...
Introduction Experts continue to debate how increase COVID-19 vaccination rates. Some experts advocate for financial incentives. Others argue that incentives, especially large ones, will have counterproductive psychological effects, reducing the percent of people who want vaccinate. Among a racially and ethnically diverse U.S. sample lower income adults, whom vaccine uptake has lagged compared with higher we empirically examine such claims about relatively small guaranteed cash payments....
Electroencephalographic seizures (ES) are common in neonates with hypoxic-ischemic encephalopathy (HIE), but identification continuous electroencephalographic (EEG) monitoring (CEEG) is resource-intensive. We aimed to develop an ES prediction model.
Abstract Objectives The use of topical corticosteroids to manage postoperative sinonasal symptoms after endoscopic skull base surgery (ESBS) has not been well studied. We quantified long‐term impact steroid irrigations (SIs) on quality life patients ESBS. Methods Retrospective review at the University Pennsylvania undergoing ESBS from 2010 2019. Data patient demographics and treatment with nasal saline irrigation twice daily without dissolved steroids (mometasone or budesonide) was...
Objectives There is growing interest in assessing patient quality of life (QOL) following treatment sinonasal tumors, including inverted papilloma (IP). We aimed to elucidate the natural history postoperative QOL outcomes IP patients treated with surgery. Methods Cases surgically at 4 tertiary academic rhinology centers were retrospectively reviewed. SNOT‐22 scores used evaluate preoperatively and postoperatively (1, 3, 6, 12 months). Repeated‐measures ANOVA assessed for differences mean...
Objective To examine long-term (>5 yr) low-frequency hearing preservation after hybrid cochlear implantation. Study Design Retrospective cross-sectional study. Setting Tertiary care center outpatient clinic. Patients All patients older than 21 years implanted with a Cochlear Hybrid L24 device from 2014 to 2021. Main Outcome Measure Changes in pure-tone average (LFPTA) were calculated at each of several time points relative the date The proportion preserved LFPTA last follow-up and...
We sought to quantify trends in operative volumes and complications of endoscopic sellar surgery before after the COVID-19 pandemic onset.We performed a retrospective analysis.TriNetX database analysis.All adults undergoing neuroendoscopy for resection pituitary tumor (Current Procedural Terminology code 62165) with diagnosis benign/malignant neoplasm gland (D35.2/C75.1) or craniopharyngeal duct (D35.3/C75.2) were included using TriNetX 2 years (pre-COVID group) (post-COVID February 17,...
To assess the impact of a novel flipped-classroom (FC) otolaryngology resident didactic curriculum on learning.Based preferences elicited in survey preferred learning styles residents, hybrid web-based and in-person FC was implemented over 6-month period 2020-2021. Resident reactions to new were assessed via second survey. Kruskal Wallis tests used compare mean stanine scores Otolaryngology Training Examination (OTE) exam for topics taught format with delivered old format.After instituting...
Abstract Objective Pituitary apoplexy (PA) is a rare condition caused by hemorrhage or infarction of the pituitary gland with associated risk cranial neuropathies, endocrinopathies, and even death. Human immunodeficiency virus (HIV) has been shown to have some association apoplexy, however, large‐scale studies not performed. Methods A retrospective cohort study subjects greater than 18 years age was performed using national TriNetX database. The general population first compared those...
Healthcare-associated infections involving surgical sites, skin trauma, and devices penetrating the are a frequent source of increased expense, hospitalization periods, adverse outcomes. Medical adhesives often employed to help protect compromised from infection secure medical devices, but can become contaminated by pathogens, exposing wounds, colonization. We aimed incorporate ceragenins, class antimicrobial agents, into silicone- polyacrylate-based with goal reducing adhesive contamination...
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Background: Aspirin exacerbated respiratory disease (AERD) is an inflammatory condition that consists of eosinophilic asthma, chronic rhinosinusitis with nasal polyps, and reactions to cyclooxygenase-1 inhibitors. therapy after aspirin desensitization (ATAD) the most extensively studied treatment paradigm for AERD. Objective: The objective was identify which time point ATAD predictive long-term outcomes as measured by 22-item Sino-Nasal Outcome Test (SNOT-22). Methods: A retrospective chart...