- Vibrio bacteria research studies
- Bacterial biofilms and quorum sensing
- Salmonella and Campylobacter epidemiology
- Antimicrobial Resistance in Staphylococcus
- Antibiotic Resistance in Bacteria
- Aquaculture disease management and microbiota
- Web and Library Services
- Pharmaceutical and Antibiotic Environmental Impacts
- Experimental Learning in Engineering
- Mechatronics Education and Applications
- Gut microbiota and health
- Streptococcal Infections and Treatments
- Engineering Education and Pedagogy
- Synthesis and biological activity
- Phenothiazines and Benzothiazines Synthesis and Activities
- Employer Branding and e-HRM
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Higher Education and Teaching Methods
- Trauma and Emergency Care Studies
- Legal and Policy Issues
- AI and HR Technologies
- bioluminescence and chemiluminescence research
- Synthesis of β-Lactam Compounds
- Traditional Chinese Medicine Analysis
- Collaboration in agile enterprises
RMIT University
2025
National University of Malaysia
2024
Shanghai Electric (China)
2024
Renji Hospital
2020-2022
Shanghai Jiao Tong University
2020-2022
Nankai University
2007-2022
Henan University
2021
Bridge University
2020
Shandong University
2020
American Society For Engineering Education
2020
Wild birds are known to harbor and discharge antibiotic-resistant bacteria (ARB) their associated antibiotic resistance genes (ARGs). However, assessments of contribution the dissemination in environment limited culture-dependent bacterial snapshots. Here, we present a high-throughput sequencing study that corroborates extensive ARG exchange between wild bird feces habitats implies need scrutinize high-mobility as potential vectors for global propagation ARGs. We characterized resistome (281...
Staphylococcus aureus (S. aureus) is a clinical pathogen of great significance causing metastatic or complicated infections. ST5 clonotype isolates have dominated S. infections for more than 10 years in Shanghai, China, and the proportion methicillin-susceptible (MSSA) has remarkably increased past decades. By whole-genome sequencing (WGS) 121 using next-generation (NGS) platforms characterizing evolutionary dynamics linages, we found that MSSA evolved independently, making it subtype...
Abstract Pneumonia caused by community-associated Staphylococcus aureus (CA-SA) has high morbidity and mortality, but its pathogenic mechanism remains to be further investigated. Herein, we identify that staphylokinase (SAK) is significantly induced in CA-SA inhibits biofilm formation a plasminogen-dependent manner. Importantly, SAK can enhance CA-SA-mediated pneumonia both wild-type cathelicidins-related antimicrobial peptide knockout ( CRAMP −/− ) mice, suggesting exacerbates...
The global increase of community-associated (CA) infections with methicillin-resistant Staphylococcus aureus (MRSA) is a major healthcare problem. Although sequence type (ST) 398 MRSA was first described as livestock-associated (LA) lineage, human-adapted (HO-MRSA) ST398 without livestock contact has subsequently been reported from China in our previous study and other later research. proportion HO-MRSA also remarkably increased recent years China. Based on 3878 S. isolates that were...
Abstract Objectives Fosfomycin resistance has become a clinical concern. In this study, we analysed the dynamic change of fosfomycin MIC in epidemic Staphylococcus aureus lineages teaching hospital Shanghai for 12 years and sought to elucidate major underlying mechanisms. Methods MLST was conducted 4580 S. isolates recovered from 2008 2019. determined by agar dilution method. The genome data 230 lineage were acquired next-generation sequencing (NGS) platform. Gene deletion corresponding...
Vibrio parahaemolyticus is an important cause of foodborne gastroenteritis globally. Thermostable direct haemolysin (TDH) and the TDH-related are two key virulence factors in V. parahaemolyticus. pathogenicity islands harbour genes encoding these haemolysins. The serotyping based on combination O K antigens. Frequent recombination has been observed parahaemolyticus, including genomic regions serotype O4:K12 caused outbreaks USA Spain. Recently, by this have reported China. However,...
Household water purifiers (HWPs) are increasingly used to clean at home, representing the last defense of chemical and microbial contaminants in drinking water. However, little is known about antibiotic resistant bacteria (ARB) resistance genes (ARGs) HWPs. Here, we quantified ARB ARGs on reverse osmosis (RO) membranes HWPs using both culture-dependent independent approaches. 84 conferring 11 antibiotics through three major mechanisms deactivation, efflux, cellular protection were detected....
Exploring digital governance is essential for grasping how technology can be employed to enhance public services, boost efficiency, and foster transparency engagement. This study aims conduct a systematic review of research in order explore its development, emerging trends, network leading researchers, countries institutions that contribute greatly this field. A bibliometric was conducted on works using the following terms: “digital governance,” “E-governance,” government,” “E-government” as...
Abstract Objectives Oxacillin-susceptible mecA-positive Staphylococcus aureus (OS-MRSA) is clinically significant and isolated globally but the mechanism of its occurrence remains indistinct. We sought to assess regulating oxacillin susceptibility in OS-MRSA isolates by evaluating evolutionary dynamics discrepancies mecA-regulating genes oxacillin-resistant MRSA (OR-MRSA). Methods Nine 77 OR-MRSA were sequenced using next-generation sequencing (NGS) platforms. Two representative (ET-13,...
The antimicrobial activity and the underlying action mechanisms of dihydrotanshinone I against Staphylococcus aureus, methicillin-resistant extended-spectrum beta-lactamases aureus were investigated with Kleihauer-Betke (K-B) test. antibacterial by monitoring changes in electric conductivity, concentration AKP, protein content, patterns electrophoretic bands sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE). rings showed that at 18 mM was stronger to than aureus. minimum...
ObjectiveTo establish a method for rapid detection of Vibrio parahaemolyticus by use the principle clustered regularly interspaced short palindromic repeats (CRISPR) and characteristics Cas12a enzyme to achieve accurate identification pathogens. MethodsIn this study, we prepared purified protein, screened constructed V. guide RNA, established CRISPR fluorescence system parahaemolyticus, determined effectiveness CRISPR-VP based on final amplification curve. ResultsIn method, significant...