A5049772337- Pain Mechanisms and Treatments
- Laser Applications in Dentistry and Medicine
- Bee Products Chemical Analysis
- Pain Management and Placebo Effect
- Venomous Animal Envenomation and Studies
- Botulinum Toxin and Related Neurological Disorders
- Acupuncture Treatment Research Studies
- Ion channel regulation and function
- Healthcare Regulation
- Music Therapy and Health
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Healthcare and Venom Research
- Long-Term Effects of COVID-19
- Marine Invertebrate Physiology and Ecology
- Neuroscience and Neural Engineering
- Transcranial Magnetic Stimulation Studies
- Dermatologic Treatments and Research
- Pediatric Pain Management Techniques
- Thermal Regulation in Medicine
- Hereditary Neurological Disorders
- Wound Healing and Treatments
- Psychosomatic Disorders and Their Treatments
- Male Reproductive Health Studies
- Healthcare during COVID-19 Pandemic
- Neuroscience and Music Perception
Universidade de São Paulo
2018-2025
Hispanics in Philanthropy
2022
Secretaria do Meio Ambiente
2022
Universidade Nove de Julho
2016
Abstract Globally, 537 million people suffer from diabetes mellitus (DM), a condition often associated with sensory disturbances, wound development, and chronic pain, which significantly affects the quality of life imposes substantial economic burden. This study evaluated effects photobiomodulation (PBM) therapy on nociceptive changes in diabetic patients to understand pain manifestations explore PBM's molecular mechanisms healing. Twenty type 2 DM underwent clinical assessments, completed...
Abstract Our study aimed to explore the potential of Photobiomodulation (PBM) as a treatment for Tendinopathy (TP), chronic condition characterized by tendon degeneration, inflammation, and pain, which current options often yield unsatisfactory outcomes. PBM, utilizing low‐level laser, has shown promise in reducing inflammatory markers, stimulating cell proliferation, alleviating thus presenting itself promising alternative therapy TP. Using an experimental rat model tendinopathy, male...
Background Envenoming induced by Bothrops snakebites is characterized drastic local tissue damage that involves an intense inflammatory reaction and hyperalgesia which are not neutralized conventional antivenom treatment. Herein, the effectiveness of photobiomodulation to reduce moojeni venom (Bmv), as well mechanisms involved was investigated. Methodology/Principal Findings Bmv (1 μg) injected through intraplantar route in right hind paw mice. Mechanical allodynia were evaluated von Frey...
Diabetic peripheral neuropathy (DPN) is a nervous disorder caused by diabetes mellitus, affecting about 50% of patients in clinical medicine. Chronic pain one the major and most unpleasant symptoms developed those patients, conventional available treatments for neuropathy, including associated pain, are still unsatisfactory benefit only small number patients. Photobiomodulation (PBM) has been gaining acceptance once it able to promote early nerve regeneration resulting significant...
Abstract Backgroud Diabetic neuropathy (DN) is one of the most common complications diabetes, affecting about half individuals with disease. Among various symptoms DN, development chronic pain stands out and manifests as exacerbated responses to sensorial stimuli. The conventional clinical treatments used for general associated painful symptoms, still brings uncomplete unsatisfactory relief. Patients neuropathic syndromes are heterogeneous. They present a variety sensory qualities which...
Chronic pain is a major health issue, and the search for new analgesics has become increasingly important because of addictive properties unwanted side effects opioids. To explore potentially drug targets, we investigated mutations in NTRK1 gene found individuals with congenital insensitivity to anhidrosis (CIPA). encodes tropomyosin receptor kinase A (TrkA), nerve growth factor (NGF) that contributes nociception. Molecular modeling biochemical analysis identified decreased interaction...
BACKGROUND AND OBJECTIVES: Hypnotic suggestions for hypoalgesia or analgesia are efficient relieving different pain conditions, presenting few no side effects. However, little is known about its direct effect on the modulation of peripheral nociception. The goal this study was to evaluate mechanical and thermal response after specific hypnotic in healthy volunteers. METHODS: This a randomized double-blinded controlled trial that aimed both nociception For this, twenty-seven participants were...