A5103188114- Animal Virus Infections Studies
- Viral gastroenteritis research and epidemiology
- Virus-based gene therapy research
- Berberine and alkaloids research
- Plant Molecular Biology Research
- Immune Cell Function and Interaction
- Photosynthetic Processes and Mechanisms
- Immunotherapy and Immune Responses
- Cancer Immunotherapy and Biomarkers
- Plant Virus Research Studies
- Plant Stress Responses and Tolerance
- Mycorrhizal Fungi and Plant Interactions
- Herpesvirus Infections and Treatments
- Plant Gene Expression Analysis
- Viral Infectious Diseases and Gene Expression in Insects
- Parasite Biology and Host Interactions
- Gut microbiota and health
- Chromosomal and Genetic Variations
- Plant Reproductive Biology
- Soil Mechanics and Vehicle Dynamics
- Ferroptosis and cancer prognosis
- Environmental and Agricultural Sciences
- Plant Pathogens and Fungal Diseases
- Microbial infections and disease research
- Mollusks and Parasites Studies
Key Laboratory of Guangdong Province
2020-2025
Agricultural Genomics Institute at Shenzhen
2018-2024
Chinese Academy of Agricultural Sciences
2013-2024
Ministry of Agriculture and Rural Affairs
2020-2024
Wen's Food Group (China)
2018-2024
University of Electronic Science and Technology of China
2024
China International Science and Technology Cooperation
2021-2023
Tianjin University of Science and Technology
2021-2023
Northwest A&F University
2021-2023
Huzhou Central Hospital
2019-2022
Sub-therapeutic antibiotics are widely used as growth promoters in the poultry industry; however, resulting antibiotic resistance threatens public health. A plant-derived promoter, Macleaya cordata extract (MCE), with effective ingredients of benzylisoquinoline alkaloids, is a potential alternative to promoters. Altered intestinal microbiota play important roles promotion, but underlying mechanism remains unknown. We generated 1.64 terabases metagenomic data from 495 chicken digesta samples...
Mikania micrantha is one of the top 100 worst invasive species that can cause serious damage to natural ecosystems and substantial economic losses. Here, we present its 1.79 Gb chromosome-scale reference genome. Half genome composed long terminal repeat retrotransposons, 80% which have been derived from a significant expansion in past million years. We identify whole duplication event recent segmental duplications, may be responsible for rapid environmental adaptation. Additionally, show M....
The golden apple snail (Pomacea canaliculata) is a freshwater listed among the top 100 worst invasive species worldwide and noted agricultural quarantine pest that causes great economic losses. It characterized by fast growth, strong stress tolerance, high reproduction rate, adaptation to broad range of environments.Here, we used long-read sequencing produce 440-Mb high-quality, chromosome-level assembly P. canaliculata genome. In total, 50 Mb (11.4%) repeat sequences 21,533 gene models were...
Oxidative stress caused by accumulation of reactive oxygen species (ROS) is capable damaging effects on numerous cellular components. Glutathione peroxidases (GPXs, EC 1.11.1.9) are key enzymes the antioxidant network in plants. In this study, W69 and W106, two putative GPX genes, were obtained de novo transcriptome sequencing salt-treated wheat (Triticum aestivum) seedlings. The purified His-tag fusion proteins W106 reduced H2O2 t-butyl hydroperoxide (t-BHP) using glutathione (GSH) or...
Fowl adenoviruses (FAdVs) are associated with many diseases, resulting in huge economic losses to the poultry industry worldwide. Since 2015, outbreaks of FAdV infections high mortality rates have been reported China. A continued surveillance FAdVs contributes understand epidemiology viruses.We isolated 155 strains from diseased chickens China between 2015 and 2018. PCR analysis determined that 123 samples were species C, 27 E, five contained two different strains. The phylogenetic...
Ethylene-responsive factors (ERFs) play important roles in plant growth and development the response to adverse environmental factors, including abiotic biotic stresses.In present study, we identified 160 soybean ERF genes distributed across 20 chromosomes that could be clustered into eight groups based on phylogenetic relationships. A highly ABA-responsive gene, GmERF75, belonging Group VII was further characterized. Subcellular localization analysis showed GmERF75 protein is localized...
Abstract Apolygus lucorum (Miridae) is an omnivorous pest that occurs worldwide and notorious for the serious damage it causes to various crops substantial economic losses. Although some studies have examined biological characteristics of mirid bug, no reference genome available in Miridae, limiting in‐depth this pest. Here, we present a chromosome‐scale A. , first sequenced Miridae species. The assembled size was 1.02 Gb with contig N50 785 kb. With Hi‐C scaffolding, 1,016 Mb sequences were...
Abstract Whole‐genome duplication (WGD), contributing to evolutionary diversity and environmental adaptability, has been observed across a wide variety of eukaryotic groups, but not in molluscs. Molluscs are the second largest animal phylum terms species numbers, among organisms that have successfully adapted nonmarine realm through aquatic–terrestrial (A‐T) transition. We assembled chromosome‐level reference genome for Achatina immaculata , globally invasive species, compared genomes two...
Abstract Background Biogas production with anaerobic digestion (AD) is one of the most promising solutions for both renewable energy and resolving environmental problem caused by worldwide increase in organic waste. However, complex structure microbiome AD poorly understood. Findings In this study, we constructed a microbial gene catalog (22,840,185 genes) based on 1,817 Gb metagenomic data derived from digestate samples 56 full-scale biogas plants fed diverse feedstocks. Among catalog,...
Since a novel hyper-virulent fowl adenovirus serotype 4 (FAdV-4) infection occurred in 2015, the FAdV-4 has been widely spreading across China, causing significant economic losses to poultry industry. As urgency of issue calls for effective and efficient solutions, present study investigated possibility fiber-2 protein serve as vaccine candidate against FAdV-4. In research, proteins were expressed Escherichia coli, then purified. To evaluate immunogenicity recombinant protein, we both...
Getah virus (GETV) is a multi-host found in pigs, horses, and blue foxes. Clinically, GETV can cause fever, diarrhea, reproductive disorders representing significant threats to pig breeding. At present, few studies have examined the pathogenicity of pigs different ages.
Avian orthoreovirus (ARV) is a significant pathogen causing viral arthritis, leading to substantial economic losses in the poultry industry worldwide. A novel ARV strain, designated FJ202311, was isolated from broiler farm Fujian Province, China. Whole-genome sequencing conducted using next-generation with MGI technology, and phylogenetic analysis of sigma C amino acid sequence performed. Comparative identified unique genetic features FJ202311. Pathogenicity studies were carried out by...
Abscisic acid (ABA) mediates various abiotic stress responses, and ethylene responsive factors (ERFs) play vital role in resisting stresses, but the interaction of these molecular mechanisms remains elusive. In this study, we identified an ABA-induced soybean ERF gene GmERF135 that was highly up-regulated by (ET), drought, salt, low temperature treatments. Subcellular localization assay showed protein targeted to nucleus. Promoter cis-acting elements analysis suggested numerous potential...
Chemotherapy induced diarrhea (CID) is a common side effect in patients receiving chemotherapy for cancer. The aim of our study was to explore the association between gut microorganisms and CID from CapeOX regimen resected stage III colorectal cancer (CRC) patients.After screening identification, 17 stool samples were collected CRC undergoing regimen. Bacterial 16S ribosomal RNA genes sequenced, bioinformatics analysis executed screen distinctive microbiome functional metabolism associated...
Mikania micrantha is a noxious invasive plant causing enormous economic losses and ecological damage. Soil microbiome plays an important role in the invasion process of M. micrantha, while little known about its rhizosphere composition function. In this study, we identified distinct microbial communities by comparing them with those two coexisting native plants (Polygonum chinense Paederia scandens) bulk soils, using metagenomics data from field sampling pot experiment. As result, enrichment...
Liver cancer is one of the most common malignant tumors in world. T cell-mediated antitumor immune response basis liver immunotherapy.To screen and analyze RNAs associated with activated memory CD4 cells CD8 cancer.ESTIMATE was used to calculate stromal scores tumor samples, which were downloaded from The Cancer Genome Atlas (TCGA). differentially expressed genes (DEGs) high low screened, followed by functional enrichment overlapped DEGs. We then conducted a survival analysis identify...
Riemerella anatipestifer (RA) causes epizootic infectious polyserositis in ducks with high mortality and leads to huge economic losses worldwide. Bacterial resistance poses a challenge for the control of disease, vaccines failed provide ideal cross-protection. Thus, preparation based on popular serotypes is important. In this study, we collected 700 brain liver tissues dead from 8 provinces southern China 2016 2022 obtained 195 RA isolates 1, 2, 7, 10. Serotypes 1 2 were most prevalent...
Litchi chinensis seed is a valuable byproduct of the subtropical fruit litchi (L. Sonn.), whose extract (LSE) has been confirmed to ameliorate dyslipidemia, hyperglycemia, and oxidative stress caused by type 2 diabetes. However, if LSE exerts an effect on anti-hypertension hypertensive renal damage remains unknown. In this study, 13 polyphenols one fatty acid were identified UPLC-Q/TOF-MS. Network pharmacological analysis revealed that therapeutic effects may be involved in multitargets...
RESEARCH HIGHLIGHTSFirst report of the epidemiology duck adenovirus 3 infection in China.Mutant DAdV-3 strains (truncated ORF67) became predominant.