A5077332261- Veterinary Oncology Research
- Infectious Diseases and Mycology
- Virus-based gene therapy research
- Oral and Maxillofacial Pathology
- Microbial infections and disease research
- Mercury impact and mitigation studies
- Cardiomyopathy and Myosin Studies
- Cancer Diagnosis and Treatment
- Heavy Metal Exposure and Toxicity
- Mast cells and histamine
- Polyamine Metabolism and Applications
- Animal Virus Infections Studies
- Bird parasitology and diseases
- Cancer-related Molecular Pathways
- Urologic and reproductive health conditions
- Xenotransplantation and immune response
- Parvovirus B19 Infection Studies
- Vector-Borne Animal Diseases
- Venomous Animal Envenomation and Studies
- Reproductive biology and impacts on aquatic species
- Cardiovascular Conditions and Treatments
- Hair Growth and Disorders
- Geochemistry and Elemental Analysis
- Microbial Inactivation Methods
- Hedgehog Signaling Pathway Studies
Istituto Zooprofilattico Sperimentale dell'Abruzzo e del Molise G. Caporale
2022-2024
University of Teramo
2016-2019
Background Osteosarcoma (OSA) should be differentiated from other less frequent primary bone neoplasms, metastatic disease, and tumor‐like lesions, as treatment prognosis can vary accordingly. Hence, a preoperative histologic diagnosis is generally preferred. This requires collection of multiple biopsies under general anesthesia, with possible complications, including pathological fractures. Fine‐needle aspiration cytology would allow an earlier significant reduction discomfort morbidity....
Rare Earth Elements (REEs) are strategical elements playing a crucial role in the industry, especially producing high-tech materials. Therefore, REEs new contaminants of emerging concerns. However, due to lack exposure data on REE occurrence environmental matrices, European countries, it is still tricky establish background levels assess ecotoxicological risk related exposure. The present study aimed evaluate liver concentrations domestic dogs (Canis lupus familiaris) and Apennine wolves...
Although there are increasing reports on the prevalence of Listeria monocytogenes in wild species, this is first case listeriosis sea turtle. An adult female Caretta caretta was rescued after being stranded alive along coast Abruzzo region (Italy) summer 2021. The turtle died 6 days due to respiratory failure. necropsy showed widespread organ lesions, such as yellow foci necrosis many organs, gastrointestinal erosions, pericarditis, and granulomatous pneumonia. Microbiological histological...
Mammary carcinomas are the most common neoplasms observed in women and female dogs. Canine mammary tumors show epidemiological, clinical, genetic, prognostic characteristics comparable to human breast cancers. The recent introduction of next generation sequencing (NGS) technologies has greatly improved research diagnostics for humans, while these new tools still need be implemented animal models. In this study we developed validated an AmpliSeq Panel assay identification BRCA variants...
Pets have a crucial role in cancer research. Specifically, dogs and cats share the same environment as their owners thus may serve sentinels of naturally occurring tumors that are linked to exposure environmental hazards. Quantitative comparison tumor types reveal unusual frequencies, providing directions for research generation hypotheses causation specific area identification risk factors. The aim this study was describe data collected by pathology-based animal registry, managed Istituto...
Alopecia X in Pomeranians is caused by a hair cycle deregulation, associated with downregulation of key regulatory genes the Wnt and Shh pathways, stem-cell markers. However, pathogenesis remains unclear. p63 an important transcription factor correlated aforementioned modulating genes.The aim this study was to highlight possible changes immunohistochemical expression within follicles canine alopecia compared normal skin.Skin biopsies from 19 X-affected six control were analysed.Serial...
Mast cells (MCs) are involved in angiogenesis, tissue remodeling and immunomodulation several human animal tumors, although their exact role is still controversial. Since no information available canine prostate carcinoma (PC) normal tissues, the aims of this study were to evaluate possible correlations between MC distribution, molecular expression microvessel density (MVD) prostatic proliferative disorders prostate. All samples (6 normal, 15 benign hyperplasia-BPH, 8 PC) stained with...
A large, ill-defined, firm, multinodular mass involving the pancreas was confirmed on postmortem examination of a 5-y-old, male Rottweiler that died following acute respiratory distress syndrome, after period anorexia and lethargy. Histologically, consisted plump spindle cells admixed with variable number macrophages, lymphocytes, plasma cells, neutrophils. Foci coagulative necrosis hemorrhage were also observed. Spindle strongly reacted to antibodies against vimentin, α–smooth muscle actin,...
Quantification of trace element concentrations in human and animal tissues has acquired great importance the last few years, considering pivotal role these elements several physiological pathological processes. Variations their appear to have a development advancement diseases both humans animals, for example, cancer. The purpose this study was investigate concentration rare earth metals healthy neoplastic Formalin-Fixed Paraffin-Embedded (FFPE) mammary gland tissue dogs. All samples were...
The virus species Protoparvovirus carnivoran 1 encompasses pathogens that infect both domestic and wild carnivores, including feline panleukopenia virus. We identified characterized strains in a Marsican brown bear (Ursus arctos marsicanus) crested porcupine (Hystrix cristata) Italy, extending the known host range of this