A5101890594- Graphene and Nanomaterials Applications
- Nanoparticle-Based Drug Delivery
- Advancements in Battery Materials
- Endometriosis Research and Treatment
- Nanoparticles: synthesis and applications
- Advanced Battery Materials and Technologies
- Advanced Battery Technologies Research
- Immune Cell Function and Interaction
- Metal-Organic Frameworks: Synthesis and Applications
- Cytokine Signaling Pathways and Interactions
- Nanoplatforms for cancer theranostics
- Pharmacological Effects and Toxicity Studies
- Organometallic Complex Synthesis and Catalysis
- Uterine Myomas and Treatments
- Estrogen and related hormone effects
- Crystallography and molecular interactions
- Gold and Silver Nanoparticles Synthesis and Applications
- Laser-Ablation Synthesis of Nanoparticles
- Whipple's Disease and Interleukins
- Molecular Junctions and Nanostructures
- Plant-derived Lignans Synthesis and Bioactivity
- Advanced Electron Microscopy Techniques and Applications
- Ferrocene Chemistry and Applications
- Analytical chemistry methods development
- Ovarian cancer diagnosis and treatment
Affiliated Zhongshan Hospital of Dalian University
2025
Institute of High Energy Physics
2020-2024
Chinese Academy of Sciences
2016-2024
University of Chinese Academy of Sciences
2022-2024
The University of Adelaide
2024
National Center for Nanoscience and Technology
2024
Harbin University of Commerce
2024
Tongji University
2021
University of Hong Kong
2021
Shenyang University of Chemical Technology
2019-2021
Abstract Background To effectively applied nanomaterials (NMs) in medicine, one of the top priorities is to address a better understanding possible sub-organ transfer, clearance routes, and potential toxicity NMs liver kidney. Results Here we explored how surface chemistry polyethylene glycol (PEG), chitosan (CS), polyethylenimine (PEI) capped gold nanoparticles (GNPs) governs their biodistribution, profiles kidney after intravenous injection mice. The PEG-GNPs maintained dispersion...
The Li<sub>0.1</sub>B<sub>0.967</sub>PO<sub>4</sub> Li<sup>+</sup>-conductive coating improves the cyclability and rate performance of Cr<sup>3+</sup>-doped LiNi<sub>0.5</sub>Mn<sub>1.5</sub>O<sub>4</sub> high potential cathode.
The absorption and oxidation reactions of SO<sub>2</sub> on TiO<sub>2</sub> nanoparticles were investigated by using a flow chamber, synchrotron X-ray near-edge structure high resolution photoelectron spectroscopy techniques.
Abstract Background Renal excretion is one of the major routes nanomaterial elimination from body. Many previous studies have found that graphene oxide nanosheets are excreted in bulk through kidneys. However, how lateral size affects GO disposition kidneys including glomerular filtration, active tubular secretion and reabsorption still unknown. Results The thin, two-dimensional (GOs) was observed to excrete urine kidneys, but dimension GOs their renal clearance pathway injury. s -GOs could...
A loss of antigen-specific T-cell responses due to defective cytokine signaling during infections has not been reported. We hypothesize that tuberculosis can destroy effects selective cytokine(s) and induce exhaustion T cells. To test this hypothesis, mechanistic studies were performed examine whether how blocked interleukin 23 (IL-23) 2 (IL-2) on a major human γδ subpopulation, phosphoantigen HMBPP–specific Vγ2Vδ2 IL-23 IL-2 significantly expanded HMBPP-stimulated cells from subjects with...
Over the past thirty years, International English Language Testing System (IELTS) exam has served as a gateway to English-speaking world, assisting countless Chinese students in achieving their aspirations of studying abroad.China, with its vast population, many whom are seeking overseas qualifications, is home multitude IELTS learning and teaching centers.These centers offer diverse range resources related methodologies, template-oriented being dominant.However, Task Response (TR)...
Hypoxia, a common occurrence within solid tumors, can stimulate the dissemination of deceptive tumor exosomes, which function as communicative bridges and orchestrate recruitment various supportive cell types for enhanced adaptability in immune microenvironment. Current nanotechnology provides us intelligent strategies to combat hypoxic However, once exposed external stimuli, such chemotherapy, cells simultaneously release malignant signals develop migration immunosuppression, posing...
An ultrathin and conformal ion conductive coating is realized on 3D current collectors for preventing the irreversible reaction between electrolyte Li metal, which has been confirmed by <italic>in situ</italic> optical observation. At high areal capacity of 10 mA h cm<sup>−2</sup> metal anode, a stable CE 98.9% 800 can be achieved.
Armillaria sp. are traditional edible medicinal mushrooms with various health functions; however, the relationship between their composition and efficacy has not yet been determined. Here, ethanol extract of liquid-cultured ostoyae mycelia (AOME), a pure wild strain, was analyzed using UHPLC-QTOF/MS, network pharmacology, molecular docking techniques. The obtained affects metabolic pathways, such as JAK/STAT PI3K/AKT. also contains important compounds...
Active form of vitamin D (VitD) enhances human innate immunity against Mycobacterium tuberculosis ( Mtb ) infection. Our previous studies showed that MIR337-3p was highly expressed in lymphocytes (TB) patients. Here, we identified the mechanism regulation fast-acting anti-TB by inhibiting VitD-dependent antimicrobial response pathways. While high-level expression induced mycobacterial infection cellular models and mice, TB patients exhibited significantly increased CD14 +...
Copolymerization of 1,3-butadiene with four 1-substituted 1,3-diene comonomers bearing amino and alkyoxy groups by a Ziegler-Natta iron(iii) catalytic system to access in-chain functionalized syndiotactic 1,2-polybutadiene is reported herein. The polar comonomer content can be easily regulated varying the loadings or polymerization conditions, affording different amounts functionalities. incorporation showed little influence on 1,2-content stereoregularity resulting polymers, giving...
High spatial resolution imaging analysis is urgently needed to explore the biodistribution, transfer and clearance profiles, biological impact of nanoparticles in body, which will be helpful clarify efficacy nanomedicine clinical applications. Herein, by combination with multiscale synchrotron-based techniques, including X-ray fluorescence (XRF) spectrometry, Fourier transform infrared (FTIR) spectroscopy, micro phase contrast computed tomography (micro-XPCT), we visually displayed patterns...
The fragile electrolyte/Li interface is responsible for the long-lasting consumption of Li resources and fast failure metal batteries. polymer artificial with high mechanical flexibility a promising candidate to maintain stability interface; however, sluggish Li-ion transportation conventional hinders application. In this work, Li-functionalized graphene oxide (GO-ADP-Li3), which synthesized by covalent grafting adenosine 5′-diphosphate lithium on GO nanosheets, used as functional additive...
Renal excretion is expected to be the major route for elimination of biomedically applied nanoparticles from body. Hence, understanding nanomedicine-kidney interaction crucially required, but it still far being understood. Herein, we explored lateral dimension- (~70 nm and ~300 nm), dose- (1, 5, 15 mg/kg in vivo 0.1~250 μg/mL vitro), time-dependent (48 h 7 d vivo) deposition injury PEGylated graphene oxide sheets (GOs) kidney after i.v. injection mice. We specially investigated cytotoxic...
Understanding the final fate of nanomaterials (NMs) in liver is crucial for their safer application. As a representative two-dimensional (2D) soft nanomaterial, graphene oxide (GO) has shown to have high potential applications biomedical field, including biosensing, drug delivery, tissue engineering, therapeutics, etc. GO been accumulate after entering body, and thus, understanding GO–liver interaction will facilitate development bio-applications. In this study, hepatic clearance two types...