A5028863296- Probiotics and Fermented Foods
- Bacteriophages and microbial interactions
- Microbial Metabolites in Food Biotechnology
- Protein Hydrolysis and Bioactive Peptides
- Listeria monocytogenes in Food Safety
- Microbial Inactivation Methods
- Food composition and properties
- Bacterial Genetics and Biotechnology
- Essential Oils and Antimicrobial Activity
- Meat and Animal Product Quality
- Enzyme Structure and Function
- Gut microbiota and health
- Bacterial biofilms and quorum sensing
- Advanced Drug Delivery Systems
- Salmonella and Campylobacter epidemiology
- Heme Oxygenase-1 and Carbon Monoxide
- Enzyme Production and Characterization
- Antibiotic Resistance in Bacteria
- Reproductive tract infections research
- Genomics and Phylogenetic Studies
- Bacillus and Francisella bacterial research
- Microbial Metabolic Engineering and Bioproduction
- Neonatal Health and Biochemistry
- Microencapsulation and Drying Processes
- Advanced Proteomics Techniques and Applications
Agriculture and Food
2016-2025
The University of Queensland
2016-2025
Queensland Health
2020-2024
University of Liverpool
2024
University Hospitals Bristol and Weston NHS Foundation Trust
2021
University Hospitals Bristol NHS Foundation Trust
2021
Health Economics and Outcomes Research (United Kingdom)
2019
ARC Centre of Excellence for Plant Success in Nature and Agriculture
2015
In-Q-Tel
2011
Queensland University of Technology
1997-2009
<h3>Objective</h3> To assess the efficacy and safety of lasmiditan in acute treatment migraine. <h3>Methods</h3> Adult patients with migraine were randomized (1:1:1) to a double-blind dose oral 200 mg, 100 or placebo asked treat their next attack within 4 hours onset. Over 48 after dosing, used an electronic diary record headache pain presence nausea, phonophobia, photophobia, one which was designated most bothersome symptom (MBS). <h3>Results</h3> Of 1,856 who treated attack, 77.9% had ≥1...
Guidelines for patients with atherosclerotic cardiovascular disease (ASCVD) recommend intensive statin therapy and adding nonstatin if low-density lipoprotein cholesterol (LDL-C) levels are 70 mg/dL or more. Compliance guidelines is often low.
Lactobacillus helveticus is a homofermentative, thermophilic starter bacterium commonly used in dairy processing to produce cheese and fermented milk. It known for enhancing flavor texture improving the final products' health benefits. L. has number of characteristic features that differentiate it from cultures, including ability metabolize galactose, high acidification rate, strong proteolytic activity. This article aims review key relevant industry, i.e., technological advantages, effects,...
Database-searching programs generally identify only a fraction of the spectra acquired in standard LC/MS/MS study digested proteins. Subtle variations database-searching algorithms for assigning peptides to MS/MS have been known provide different identification results. To leverage this variation, probabilistic framework is developed combining results multiple search engines. The scores each engine are first independently converted into peptide probabilities. These probabilities can then be...
Probiotic bacteria can provide health benefits when delivered in functional foods. This study involved isolation of lactic acid (LAB) from traditionally dried and salted anchovy fish characterization their survival simulated gastrointestinal digestion. Promising strains were used to prepare fermented sausages which then evaluated for cytotoxicity activity against two cancer cell-lines, antidiabetic as determined by α-amylase α-glucosidase inhibition, antioxidant proteolytic activities vitro,...
To increase uptake of algae into food products, it is essential to understand aroma and flavour components in optimise their sensory properties suit various applications. Volatile analysis a promising tool for identification suitable application future development. This review identified key aroma-active volatile compounds across fifteen species; the impact taxonomy, environment as well processing methods on those profiles discussed. In addition, allow quality assessment algae. includes...
With the increasing availability of de novo sequencing algorithms for interpreting high-mass accuracy tandem mass spectrometry (MS/MS) data, there is a growing need programs that accurately identify proteins from results. De sequences derived spectra peptides often contain ambiguous regions where exact amino acid order cannot be determined. One problem this poses sequence alignment difficulty in distinguishing discrepancies due to errors actual genomic variation and posttranslational...
Algorithms that can robustly identify post-translational protein modifications from mass spectrometry data are needed for data-mining and furthering biological interpretations. In this study, we determined a mass-based alignment algorithm (OpenSea) de novo sequencing results could post-translationally modified peptides in high-throughput environment. A complex digest of proteins human cataractous lens, tissue containing high abundance proteins, was analyzed using two-dimensional liquid...
During construction of several gene deletion mutants in Lactococcus lactis MG1363 which involved a high-temperature (37.5°C) incubation step, additional spontaneous mutations were observed resulted stable heat resistance and some cases salt-hypersensitive phenotypes. Whole-genome sequencing one strain was both resistant salt hypersensitive, followed by PCR four other shared these phenotypes, revealed independent llmg_1816 all cases. This encodes membrane-bound stress signaling protein the...
Summary The second messenger cyclic‐di‐adenosine monophosphate ( c‐di‐AMP ) plays important roles in growth, virulence, cell wall homeostasis, potassium transport and affects resistance to antibiotics, heat osmotic stress. Most F irmicutes contain only one c‐di‐ AMP synthesizing diadenylate cyclase CdaA ); however, little is known about signals effectors controlling activity levels. In this study, a genetic screen was employed identify components which affect the level L actococcus . We...
The broadly conserved bacterial signalling molecule cyclic-di-adenosine monophosphate (c-di-AMP) controls osmoresistance via its regulation of potassium (K+) and compatible solute uptake. High levels c-di-AMP resulting from inactivation phosphodiesterase activity leads to poor growth bacteria under high osmotic conditions. To better understand how can adjust in response excessive identify signals that feed into the network, we characterised genes identified a screen for osmoresistant...