A5044614958- Mesenchymal stem cell research
- Phytochemicals and Antioxidant Activities
- Educational Methods and Media Use
- Medicinal Plant Research
- Edcuational Technology Systems
- Natural Antidiabetic Agents Studies
- Food and Agricultural Sciences
- Decision Support System Applications
- Public Health and Nutrition
- Curcumin's Biomedical Applications
- Educational Methods and Outcomes
- Essential Oils and Antimicrobial Activity
- Electrospun Nanofibers in Biomedical Applications
- Multimedia Learning Systems
- Management and Optimization Techniques
- Cancer Cells and Metastasis
- STEM Education
- Tissue Engineering and Regenerative Medicine
- COVID-19 Prevention and Impact
- Tea Polyphenols and Effects
- Phytoestrogen effects and research
- Drug-Induced Hepatotoxicity and Protection
- Skin Protection and Aging
- Computational Drug Discovery Methods
- Data Mining and Machine Learning Applications
University of Indonesia
2019-2024
Padjadjaran University
2024
Universitas Halu Oleo
2020-2023
Politeknik Kesehatan Kementerian Kesehatan Jakarta II
2023
Tanjungpura University
2020-2023
Tadulako University
2014-2022
Universitas Muhammadiyah Buton
2022
Universitas Prima Indonesia
2022
Sebelas Maret University
2021
Malikussaleh University
2013-2020
Diabetes Mellitus (DM) is hyperglycemic or elevated blood glucose level and deficiency of insulin level. DM treatment using synthetic drugs has several complexities, side effects. Reducing the effects drugs, utilization herbal medicines increasingly in demand. Butterfly pea flower (Clitoria ternatea L.) extract (CTE) pharmacological activities such as hepatoprotective, diuretic, antioxidant, antidiabetic, anti-inflammatory activities. Objective : This research was conducted to evaluate...
Introduction: Breast cancer is one of the leading cause deaths in women. Metastasis BC caused by immuno- surveillance deficiency, such NK cell maturation, low activity and decreasing cytotoxicity. This study was performed to improve activating receptors cytotoxicity cells using interleukins (ILs).
 Methods: Human recombinant IL-2, -15, -18 were used induce cells. We measured inhibiting receptors, proliferation cells, on (MCF7). The effects ILs tested CD314, CD158a CD107a with...
Skin aging is a complex natural process characterised by gradual diminishment of structural integrity and physiological imbalance the skin tissue. Since oxidative stress tightly corelated to process, usage antioxidant may serve as favourable strategies for slowing down process. Mangosteen an important fruit commodity its extract had been extensively studied revealing various biological activities. Present study aimed assess antiaging activity mangosteen peel (MPE) phytochemical compounds....
Background: Skin aging is a condition where skin unable to retain both its physiological and structural integrity. Plants the main source of phtytochemicals compound with wide range biological activities. Through efforts ongoing scientific researches, an increasing number plant extracts phytochemicals have been showed promising result as anti-aging agent. Snake fruit (Salacca zalacca (Gaert.) Voss) tropical belongs palm tree family (Arecaceae) that served important crop in Indonesia. Despite...
Ocimum sanctum (OS) is tropical herbal plant which easy to find and widely used as a vegetable food in Indonesia. In last decade, lung adenocarcinoma was top position male cancer disease Recently, emerging data showing the extracts of different species exhibiting anti-tumor properties. Further studies on lewis carcinoma demonstrated pro-apoptosis effects after treatment with extracts. However, effect OS Indonesian origin human alveolar pulmonary A549 cells remain unclear. Therefore, we aimed...
Abstract Inflammation response is related with various diseases. One of the useful therapeutic method to suppress inflammatory mediator synthesis by application compounds isolated from herbal medicine as treatment for The aim this study was analyse anti-inflammatory activity black soybean extract (BSE), daidzein, and genistein trough in vitro analysis mediators such prostaglandin 2 (PGE2) cytokines interleukin 1β (IL-1β), tumor necrosis factor α (TNF-α). Safety samples determined viability...
There would be over 600 million people living with diabetes by 2040 as predicted the World Health Organization. Diabetes is characterized raised blood sugar and insulin resistance. Insulin regulates influx of glucose into cell upregulating transporter type 4 (GLUT4) expression on plasma membrane. Besides, PPAR-γ also controls metabolism in adipose tissues. Curcuma mangga Val., denoted C. mangga, a native Indonesian medicinal plant that has many beneficial effects, including an antidiabetic...
Abstract This research aims to understand how students’ perceptions and lecturers regarding the use of ICT in learning Local History at Historical Education Study Program Faculty Social Sciences, Makassar State University. uses a qualitative approach with case study design. Data collection techniques carried out, including observations, interviews, documentation literature. analysis was out using model developed by Mile Huberman, which is collecting data, data reduction, display, drawing...
Chronic kidney disease (CKD) happens due to decreasing function. Inflammation and oxidative stress have been shown result in the progression of CKD. Quercetin is widely known various bioactivities including antioxidant, anticancer, anti-inflammatory activities.To evaluate activity quercetin inhibit inflammation, oxidative, fibrosis on CKD cells model (mouse mesangial induced by glucose).The SV40 MES 13 were plated a 6-well plate with cell density at 5,000 cells/well. The medium had...
Lead (Pb) can be a cause of oxidative stress, because it is toxin found in the environment and have harmful effect on body. increased reactive oxygen species (ROS) nitrogen (RONS) levels cellular aging inflammation. natural compound plant one sources antioxidant anti-inflammatory agent that has ability to prevent including chlorogenic acid (CA). Cytotoxicity assay CA against fibroblast cells (BJ) was conducted using MTS...
Guazuma ulmifolia, or commonly known as the bastard cedar, has many pharmaceutical activities and is, therefore, claimed a source of various plant-based medicines. This reserach was purposed to identify antioxidant ethanolic extract G. ulmifolia (EEGU) by phytochemical screening assay, total flavonoid phenolic testing, comparative analysis between EEGU epicatechin. The qualitative assay detected availability phenols, flavonoids, alkaloids, tannins, terpenoids, but not saponins triterpenoids....
Propolis is a naturally produced resinous mixture the bees are secreted through collecting resin of plants, buds, and exudates. According to several studies, propolis possessed various properties, one which known as immunomodulatory property. Immunomodulatory property can be assessed observed anti-inflammatory cytotoxicity properties propolis. In Indonesia, Tetragonula sapiens (T. sapiens) from Sulawesi considered most commercial productive bees. Despite their productivity commerciality,...
Skin aging is a complicated natural phenomenon characterized by progressive loss of structural integrity and physiological function the skin. Snake fruit (Salacca zalacca) an important crop native from Indonesia. Its waste potential sour.
Abstract Antioxidants in chemical terms are electron donors and antioxidants biologically compounds that can overcome the negative effects of oxidants body such as damage to vital cells body. The balance between is very important. Antioxidant from natural sources safer than synthetic antioxidants. Soybeans functional food source contains essential amino acids, vitamin e, saponins rich flavonoids, isoflavones anthocyanins. aim this research investigate antioxidant potential ethanolic extract...
Aging is a natural process in human life and triggered by the presence of free radicals (ROS). The use antioxidants from ingredients one breakthroughs to overcome aging counteract harmful effects caused radicals. This study aimed determine compare antioxidant activity H2O2 scavenging hyaluronidase inhibition red dragon fruit peel extract (DFPE) kaempferol-3-o-rutinoside (KOR) compounds. Dragon obtained through extraction maceration method using 70% ethanol solvent. design this included...
Background: People with diabetes mellitus in Indonesia are predicted to increase until 2035. High glucose body (hyperglycemia) leads increased fibronectin synthesis. Fibronectin that gets accumulated glomerulus (mesangial cells), at the end, will lead diabetic glomerulosclerosis. Jati belanda (Guazuma ulmifolia L.) leaf is well known as an Indonesian traditional medicine have effects antidiabetic by presence of its secondary metabolites such alkaloid, tannin, saponin, flavonoid, and...
Osteosarcoma is a highly malignant primary tumor on bone that mainly attacks children and young adolescents. Until now, osteosarcoma therapy still combines some high costs invasive modalities may give side effects, such as pain nausea. Our previous studies suggested non-contact electric field has anti-proliferative effect breast cancer cells, in vitro vivo. In this study, we were interested studying alternating current effects cells progression well its potential cytotoxic effects. MG-63...
Diabetic nephropathy (DN) is a chronic kidney failure, which may lead to fatality. Mesangial cell proliferation, renal inflammation, stress oxidative, and fibrosis are involved in DN progression. Yacon leaves (Smallanthus sonchifolius (Poepp.) H. Rob.) contains large amounts of phenolic compounds it has the ability inhibit oxidative stress, fibrosis. Considering potential yacon extract (YLE), be used for treatment. This research aimed elucidate YLE's as anti-DN through anti-inflammatory,...
Acute respiratory distress syndrome (ARDS) is a type of lung failure caused by fluids and hypoxemia. Mesenchymal stem cells (MSCs) have been shown to decrease levels pro-inflammatory mediators inflammatory cells. These anti-inflammatory, anti-apoptotic, anti-microbial activity, protect against injury.This research evaluated the potential human Wharton's jelly MSCs (hWJMSCs) inhibit inflammation apoptosis in lipopolysaccharide (LPS)-induced rat (L2).hWJMSC treatment LPS-induced was performed...
BACKGROUND: Oxidative stress is closely related to all aspects of cancer. Cosmos caudatus ethanolic extract (CCEE) has been proved have antioxidant effect that inhibited cancer cell growth due its bioactive compounds such as catechin, quercetin and chlorogenic acid. This study aimed evaluate anticancer activity CCEE compounds.METHODS: Total phenol was measured according the Folin-Ciocalteu method. Catechin, acid contained in were identified by high-performance liquid chromatography (HPLC)....
Osteoarthritis (OA) is a chronic disease of the joints and bones due to trauma or other joint-related diseases (secondary). Synovial inflammation commonly causes disturbance in joint homeostasis, which associated with OA. Enzymes such as aggrecanase metalloproteinase generate cartilage damage, mediated by tumor necrosis factor (TNF-α) interleukin (IL)-1. Pro-inflammatory cytokines, including TNF-α, IL-1β, IL-6, are responsible for regulation extracellular matrix, degradation, apoptosis...
Abstract Wharton’s Jelly is one of the best sources for mesenchymal stem cells. Human Mesenchymal Stem Cells (hWJ-MSCs) have high proliferation, multi-lineage differentiation potential, and do not produce any teratogen or carcinogen. These characteristics make hWJ-MSCs become suitable regenerative medicine. Some methods were developed to isolate from umbilical cord, such as explant method enzymatic method. This study aims characterize which are isolated by two different methods, attachment...
<p>Produksi telur ayam ras di Indonesia baru mencukupi kebutuhan pasar dalam negeri sebesar 65% sedangkan sisanya dipenuhi dari kampung, itik, dan puyuh. Produksi Kabupaten Jember masih tergolong kecil dibandingkan dengan daerah-daerah lain Jawa Timur. Salah satu upaya untuk meningkatkan kapasitas produksi peternakan petelur khususnya yaitu sumber daya manusia melalui peran, inovasi kinerja penyuluh keberdayaan peternak petelur. Tujuan penelitian ini menganalisis pengaruh terhadap...