A5103233263- Breast Cancer Treatment Studies
- Breast Implant and Reconstruction
- Breast Lesions and Carcinomas
- Estrogen and related hormone effects
- Metastasis and carcinoma case studies
- Cancer Treatment and Pharmacology
- HER2/EGFR in Cancer Research
- Cancer Risks and Factors
- Ear and Head Tumors
- Reconstructive Surgery and Microvascular Techniques
- Gut microbiota and health
- Thyroid Cancer Diagnosis and Treatment
- Salivary Gland Tumors Diagnosis and Treatment
- Cancer Diagnosis and Treatment
- Obstructive Sleep Apnea Research
- Cancer and Skin Lesions
- Advanced Breast Cancer Therapies
- Chemotherapy-induced cardiotoxicity and mitigation
- Cancer Genomics and Diagnostics
- Dysphagia Assessment and Management
- Biochemical effects in animals
- Paraoxonase enzyme and polymorphisms
- Voice and Speech Disorders
- Esophageal Cancer Research and Treatment
- Cancer Immunotherapy and Biomarkers
Ewha Womans University
2013-2024
National Cancer Center
2023
Ewha Womans University Medical Center
2019-2022
Sungkyunkwan University
2020
Yeungnam University
2020
Kyungpook National University
2020
Gachon University Gil Medical Center
2014-2020
Catholic University of Korea
2020
Gangdong University
2020
Deleted Institution
2016-2017
To investigate the efficacy of health coaching and a web-based program on survivor physical activity (PA), weight, distress management among stomach, colon, lung breast cancer patients.This randomised, controlled, 1-year trial conducted in five hospitals recruited survivors within 2 months completing primary treatment who had not met ≥1 these behavioural goals: (i) conducting moderate PA for at least 150 minutes/week or strenuous exercise over 75 minutes per week or, case patients, low...
Conclusion: Percutaneous steroid injection (PSI) may be a useful alternative modality for treatment of benign vocal fold lesions. Objectives: When patients refuse general anesthesia or voice therapy diseases (Reinke's edema, polyp, nodule, and scarring), there are no other options available. We conducted an analysis the effects PSI as diseases. Methods: From October 2008 to March 2010, 130 with disease who refused showed response underwent PSI. this group, present study included 115...
The incidence of thyroid cancer has dramatically increased over the last few decades, and up to 60% patients have multifocal tumors. However, prognostic impact multifocality in with papillary carcinoma (PTC) remains unestablished controversial. We evaluate whether can predict recurrence PTC. A total 1249 who underwent thyroidectomy for PTC at Ewha Medical Center between March 2012 December 2019 were reviewed. In this study, was found 487 (39.0%) mean follow-up period 5.5 ± 2.7 years....
Human apurinic/apyrimidinic endonuclease 1 (APE1) is an essential protein for DNA base excision repair (BER) and redox regulation. The ability of cancer cells to recognize damage initiate important mechanism therapeutic resistance. Several recent studies have suggested that APE1 expression levels and/or subcellular dysregulation may be used indicate the sensitivity tumors radiotherapy or chemotherapy. In this study, we assessed prognostic significance differences in according breast...
The purpose of this study was to determine prognostic factors influencing outcomes surgical treatment in patients with T4a hypopharyngeal cancer. present enrolled 93 diagnosed cancer who underwent primary surgery between January 2005 and December 2015 at six medical centers Korea. Primary tumor sites included pyriform sinus 71 patients, posterior pharyngeal wall 14 postcricoid region 8 patients. Seventy-two received postoperative radio(chemo)therapy. Five-year disease-free survival (DFS)...
The response rate to treatment with trastuzumab (Tz), a recombinant humanized anti-HER2 monoclonal antibody, is only 12–34% despite demonstrated effectiveness on improving the survival of patients HER2-positive breast cancers. Selenium has an antitumor effect against cancer cells and can play cytoprotective role normal cells. This study investigated selenium mechanism in relation Tz. cell lines, SK-BR-3 as trastuzumab-sensitive cells, JIMT-1 Tz-resistant were treated Tz sodium selenite...
MEK-ERK pathway plays major roles in the progression of thyroid cancer, while use inhibitors has been limited by its toxicity. We investigated effect sodium selenite as an adjunct for to avoid toxicity ERK inhibitors.TPC1, 8505C and HTori-3 cells were treated with U0126 (MEK-ERK inhibitor) cell viability was counted Neubauer chamber. The synergistic effects also measured. expression ERK, p-ERK, p90RSK determined western blot.Treatment inhibited proliferation TPC1 a dose-dependent manner....
Clinical pathways have been proposed as a way to improve organizational efficiency and maximize patient outcomes. However, little is known whether clinical pathway effective for thyroid cancer.The study subjects included 216 patients who were managed after implementation 145 control patients. Length of stay, cost per patient, nurses' satisfaction compared in the 2 groups.Mean length stay was 0.8 days shorter group than (2.9 vs 3.7 days; P = .023). Cost also lower (USD $3953.00 USD $4636.00;...
Background Doxorubicin is a highly effective anti-cancer drug that causes left ventricular (LV) dysfunction and induces late-onset cardiomyopathy. However, an clinically applicable preventive treatment yet to be discovered. Objective Cardiac-Extracorporeal shockwave therapy (C-ESWT) has been suggested treat inflammatory ischemic diseases protect cardiomyocytes from doxorubicin-induced This study aims assess the safety efficacy of C-ESWT in prevention subclinical cardiotoxicity. Methods We...
Abstract Background In estrogen receptor (ER)-positive breast cancer (BC), young age is associated with poor prognosis. While very patients respond better to chemotherapy, chemotherapy less effective in ER-positive tumors than ER-negative tumors. The authors tried evaluate response of BC by pathologic complete (pCR) after neoadjuvant excluding the effect endocrine treatment extent possible. Methods We collected individual patient data from 1992 2013 Korean Breast Cancer Society (KBCS). Total...
BACKGROUND:Metastasis to the stomach can be found as first presentation of breast cancer, although it is very rare. The authors report an unusual case metastasis which had a good prognosis. CASE REPORT:A 51-year-old female underwent radical subtotal gastrectomy and chemotherapy because gastric cancer with distant metastasis. At time diagnosis she negative result from routine mammography. One year later, newly detected lesion on mammography was confirmed cancer. Initial changed metastatic...
Selenium is an essential microelement in animals including human. plays important role cellular functions such as deoxygenation and detoxification. Also, it can be used treatment of cardiac disease, hepatic AIDS various cancers. Recent meta-analysis showed that high selenium exposure was associated with decreased risk several has effect on anticarcinogesis through mechanisms, which are regulation cell cycles, apoptosis, DNA damage repair, inhibition adhesion migration, anti-angiogenesis...
Previously the authors reported age-related changes in activities of anti-oxidative enzyme and protein expressions tongues rats. Because more information is required about relations between aging oxidative stress efficiency, investigated differences expression master regulator enzymes (nuclear factor erythroid 2-related 2 [Nrf2]), levels reactive oxygen species (ROS), mitochondrial structures young aged Fischer 344 rats.Age-dependent Nrf2 ROS were determined by Western blotting using...
Objectives Antioxidative enzyme efficiency changes in some organs with age. However, no study has been conducted on age-related antioxidant tongue. In the present study, authors investigated activities of four antioxidative enzymes and their protein expressions tongues young old Fischer 344 rats. Methods Age-dependent total superoxide dismutase (SOD), Mn-SOD, Cu/Zn-SOD, catalase (CAT), glutathione peroxidase (GPx) were determined using chemical kits, levels these by Western blotting. The was...
Dendritic cells (DC) are a class of bone marrow-derived found in the blood, epithelia, and lymphoid tissues, most efficient antigen presenting cells. The number function DC can change dramatically cancer patients. aim this study is to correlate levels circulating subsets with clinical characteristics breast patients.Peripheral blood samples were collected from 53 untreated patients before surgery between January 2013 November 2013. Forty-one healthy, age-matched volunteers served as control...
BACKGROUND:Differentiating a distant lesion in breast cancer patients can be challenging. Although pleural schwannoma patient is unusual, clinicians may encounter many similar benign lesions mimicking metastatic cancer. CASE REPORT:Herein, we present the case of 62-year-old female who developed on her pleura, which was suspected as metastasis CONCLUSIONS:Our highlights need to keep mind non-malignant diagnosis those with malignancies, such
Multifocality increases the risk of recurrence in patients with papillary thyroid carcinoma (PTC); however, it is unclear whether multifocality justifies more extensive or aggressive surgical treatment. Here, we evaluated effect operative extent on recurrence-free survival (RFS) multifocal PTC. Between 2010 and 2019, 718 unilateral PTC were enrolled; 115 (16.0%) underwent ipsilateral lobectomy, 606 (84.0%) total thyroidectomy. With a mean follow up 5.2 years, RFS was comparable between...
Background and Objectives Optimal electrical power required for diathermy during tonsillectomy has not been determined. The aim of this pilot study was to evaluate compare surgical outcomes using settings at 15 watts (W) 25W monopolar microdissection bipolar hemostasis tonsillectomy. Subjects Method This prospective, single-center, single-blind, randomized conducted on 92 patients who underwent 15W or Operation times, post-operative pain severities, rates hemorrhage were compared between the...