A5021281461- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Structural Anomalies and Repair
- Cardiac Valve Diseases and Treatments
- Tissue Engineering and Regenerative Medicine
- Mechanical Circulatory Support Devices
- Aortic Disease and Treatment Approaches
- Healthcare Policy and Management
- Pluripotent Stem Cells Research
- Cardiac and Coronary Surgery Techniques
- Meningioma and schwannoma management
- Aortic aneurysm repair treatments
- Cardiac Fibrosis and Remodeling
- Congenital heart defects research
- Infective Endocarditis Diagnosis and Management
- Health and Medical Research Impacts
- Digital Games and Media
- Artificial Intelligence in Games
- Heart Failure Treatment and Management
- Pituitary Gland Disorders and Treatments
- Emergency and Acute Care Studies
- Electrospun Nanofibers in Biomedical Applications
- Artificial Intelligence in Healthcare and Education
- Mesenchymal stem cell research
- Head and Neck Surgical Oncology
- Cardiac Arrest and Resuscitation
Baylor College of Medicine
2018-2024
University of British Columbia
2010-2024
National Heart Lung and Blood Institute
2021
Rice University
2021
Cornell University
2015-2017
Memorial Sloan Kettering Cancer Center
2015-2017
University of Glasgow
2017
New Mexico Cancer Center
2016
University of New Mexico
2016
UNM Comprehensive Cancer Center
2016
We consider discrete bilevel optimization problems where the follower solves an integer program with a fixed number of variables. Using recent results in parametric programming, we present polynomial time algorithms for pure and mixed problems. For case leader's variables are continuous, our algorithm also detects whether infimum cost fails to be attained, difficulty that has been identified but not directly addressed literature. In this case, it yields "better than fully time" approximation...
Immune modulatory alginate encapsulation platform can be used in the pericardial space to provide enhanced therapeutic efficacy heart.
Abstract BACKGROUND Recurrence rates for atypical and anaplastic meningiomas range between 9% 50% after gross total resection 36% 83% subtotal resection. Optimal treatment of recurrent exhibiting atypical/anaplastic histology is complicated because they are often refractory to both surgery radiation. OBJECTIVE To evaluate clinical determinants recurrence treatment-specific outcomes in patients with at our institution. METHODS A cohort study was conducted using data all treated first January...
Safety-net hospitals (SNHs) provide essential services to predominantly underserved patients regardless of their ability pay. We hypothesized that who underwent coronary artery bypass grafting (CABG) would have inferior observed outcomes at SNHs compared with non-SNHs but matched cohorts comparable outcomes.We queried the Nationwide Readmissions Database for isolated CABG from 2016 2018. ranked by percentage all admissions in which patient was uninsured or insured Medicaid; top quartile were...
Multiple congenital or developmental anomalies associated with the central nervous system have been reported in English Bulldogs. The purpose of this retrospective study was to identify and describe prevalence MRI characteristics these their association presence degree cerebral ventriculomegaly. Magnetic resonance imaging studies 50 Bulldogs were evaluated. Forty‐eight dogs had some ventriculomegaly, 27 which an otherwise normal brain. Presence lateral ventriculomegaly not significantly...
Coronary arteriography and left ventriculography, performed in a 42-year old patient with unstable angina seven months after myocardial infarct showed communications from both the anterior descending right coronary arteries to ventricular chamber. The area of communication corresponded site infarction as established by electrocardiogram ventriculogram. Whether this is congenital or acquired lesion unclear.
We examined readmissions and resource use during the first postoperative year in patients who underwent thoracic endovascular aortic repair or open surgical of Stanford type B dissection.
Abstract Direct cell reprogramming represents a promising new myocardial regeneration strategy involving in situ transdifferentiation of cardiac fibroblasts into induced cardiomyocytes. Adult human cells are relatively resistant to reprogramming, however, likely because epigenetic restraints on gene activation. We hypothesized that modulation the regulator p63 could improve efficiency cardio-differentiation. qRT-PCR analysis demonstrated significantly increased expression panel cardiomyocyte...
Abstract Fibroblast reprogramming offers the potential for myocardial regeneration via in situ cell transdifferentiation. We explored a novel strategy leveraging endothelial plasticity to enhance efficiency. Rat cardiac cells and fibroblasts were treated with Gata4, Mef2c, Tbx5 (GMT) assess cardio-differentiation of these cells. The transdifferentiation factor ETV2 was transiently over-expressed followed by GMT treatment “trans-endothelial” cardio-differentiation. Endothelial generated more...
A 7-month old infant presented with an effusion and multiple lesions in his spleen. diagnosis of lymphangiomatosis was made based on chylous MRI demonstrating numerous enhancing within the spleen T2-weighed images. Conservative measures, including withdrawal feeds octreotide, did not significantly reduce rate chyle production increasing requirement for respiratory support. Resection patient's partial pleurectomy were associated a dramatic improvement condition. At 27 months patient well no...
Bariatric surgery helps many morbidly obese patients lose substantial weight. However, few data exist on its long-term safety and effectiveness in who also have continuous-flow left ventricular assist devices whom heart transplantation is contemplated. We retrospectively identified at our institution had undergone device implantation subsequent laparoscopic sleeve gastrectomy from June 2015 through September 2017, we evaluated their baseline demographic data, preoperative characteristics,...
You're driving along the freeway during rush hour. running late and find yourself in bumper-to-bumper traffic. You have 3 options: (1) do nothing, suffer with anguish inside; (2) productive ways to pass time, like listen a podcast or talk on phone; (3) get off next exit an alternative, roundabout path your destination. Similarly, patients suffering from coronary artery disease can opt nothing; stop progression treat their symptoms medical therapy; undergo revascularization either...
See also Clinical Commentary by Holmes
We examined the effect of frailty on in-hospital mortality, readmission rates, and hospitalization costs after transcatheter surgical aortic valve replacement in a population-level cohort.