A5067675329- Dental Radiography and Imaging
- Inflammasome and immune disorders
- Dental Implant Techniques and Outcomes
- Bone Metabolism and Diseases
- Bone health and treatments
- Orthodontics and Dentofacial Orthopedics
- dental development and anomalies
- Endodontics and Root Canal Treatments
- Retinal Diseases and Treatments
- Bone fractures and treatments
- Retinopathy of Prematurity Studies
- Plant pathogens and resistance mechanisms
- Magnesium in Health and Disease
- Caveolin-1 and cellular processes
- Cancer-related gene regulation
- Aquaculture Nutrition and Growth
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Dental Trauma and Treatments
- Nuclear Structure and Function
- Cardiac Health and Mental Health
- Genetic Associations and Epidemiology
- Exercise and Physiological Responses
- Transgenic Plants and Applications
- interferon and immune responses
- Cholinesterase and Neurodegenerative Diseases
Tianjin Medical University
2013-2024
Shanghai Institute of Nutrition and Health
2020-2022
University of Chinese Academy of Sciences
2015-2022
Inner Mongolia Agricultural University
2022
Guiyang Medical University
2022
Shenzhen Sixth People's Hospital
2022
Shanghai Institutes for Biological Sciences
2020
Central Hospital of Zibo
2018
Jinan Stomatological Hospital
2018
Wuhan University
2016
The neovascular form of age-related macular degeneration (nvAMD) is the leading cause blindness in elderly population. Vascular endothelial growth factor (VEGF) plays a crucial role choroidal neovascularization (CNV), and anti-VEGF therapy recommended as first-line for nvAMD. However, many patients do not radically benefit from this therapy. Epidemiological data suggest that physical exercise beneficial human diseases, including Yet, its protective mechanism therapeutic potential remain...
Glioblastoma (GBM), the most malignant type of astrocytic tumor, is one deadliest cancers prevalent in adults. Along with tumor growth, patients GBM generally suffer from extensive cerebral edema and apparent symptoms intracranial hyper-pressure. Accumulating evidence has demonstrated that circRNA plays a critically important role tumorigenesis progression. However, biological function underlying mechanism remain elusive. In this study, by conducting gene expression detection based on 15...
Abstract Background Mammalian skeletal muscles consist of two main fibre types: slow‐twitch (type I, oxidative) and fast‐twitch IIa, fast oxidative; type IIb/IIx, glycolytic). Muscle composition switch is closely associated with chronic diseases such as muscle atrophy, obesity, II diabetes athletic performance. Prostaglandin D 2 (PGD ) a bioactive lipid derived from arachidonic acid that aggravates damage wasting during atrophy. This study aimed to investigate the precise mechanisms...
Abstract Background Investigating the molecular biology underpinning early-stage of traumatic temporomandibular joint (TMJ) ankylosis is crucial for discovering new ways to prevent disease. This study aimed explore dynamic changes transcriptome from intra-articular hematoma or newly generated ankylosed callus during onset and early progression TMJ ankylosis. Methods Based on a well-established sheep model bony ankylosis, genome-wide microarray data were obtained samples at postoperative Days...
Calcium, magnesium, potassium, sodium, chloride and phosphorus are the major dietary minerals involved in various biological functions commonly measured blood serum. Sufficient mineral intake is especially important for children due to their rapid growth. Currently, genetic mechanisms influencing serum levels poorly understood, children. We carried out a genome-wide association (GWA) study on 5,602 European-American 4,706 African-American who had measures available electronic medical records...
Sinus augmentation with a lateral window technique and delayed implant placement are the traditional treatment schedules when residual alveolar bone height in atrophic posterior maxilla is less than 5 mm. This article presents transcrestal approach (TWA) to replace missing first molar an maxillary ridge 1 2 mm of (RBH). Transcrestal sinus were performed. The antral pseudocyst that was located nasal wall disappeared cone-beam computer tomography images taken after elevation surgery. 1-year...
Purpose: Multifactorial interventions to prevent falls are relatively less effective in the elderly with dementia. We hypothesize that primitive posture reflex associated dental occlusion may play an important role preventing persons To demonstrate this, we compared incidence of individuals and without occlusion.Methods: This study was conducted at a special geriatric hospital for patients severe dementia Hiroshima, Japan. One hundred forty-six ambulatory institutionalized subjects (42 male...
Major depressive disorder (MDD) is associated with a significant burden of disease in China. Awareness and better access to treatments could help alleviate the MDD. Because variations have been observed pharmacokinetics (PK) antidepressants across different races ethnicities, evaluation clinical pharmacology vortioxetine diverse populations remains important assess potential need for dose adjustments. Data were pooled from two phase I open-label PK studies healthy Chinese subjects, one III...
Bone nonunion is a special fracture complication that occurs in about 5% to 10% of cases. This type difficult heal, and causes great pain patients affects their quality life. The mechanism bone not clear. In our study, we investigated the influence Toll-like receptor (TLR)-3, TLR-4, Wnt signaling pathways on occurrence nonunion.Firstly, established Sprague Dawley (SD) rat model femoral nonunion, detected expression levels TLR-3, β-catenin, nemo-like kinase (NLK), c-Jun N-terminal (JNK),...
Using genomic DNA from 79 F1 plants resulted a crossing between parents with strong and weak grazing tolerance in Medicago falcata L., we generated an EcoRI restriction site-associated (RAD) sequencing library. After assembly, high-density genetic map high-quality SNP markers was constructed, total length of 1312.238 cM average density 0.844 SNP/cM. The phenotypic traits families were observed the QTLS 6 analyzed by interval mapping. Sixty three QTLs identified for seven LOD values 3 to...
This study aimed to investigate the application of an osteotomy template and a repositioning manufactured by three-dimensional (3D) printing technique in maxillary LeFortⅠosteotomy.The patient group consisted eight patients with hypoplasia who underwent LeFortⅠosteotomy. The mean age at time surgery was 25.6 years old. All were scanned using cone beam computed tomography (CBCT) create 3D model maxillary. templates LeFortⅠosteotomy technique. bones cut same doctor extensive orthognathic...