A5112258304- Peanut Plant Research Studies
- Soybean genetics and cultivation
- Plant Virus Research Studies
- Cancer-related molecular mechanisms research
- Advances in Cucurbitaceae Research
- Circular RNAs in diseases
- Genetics and Neurodevelopmental Disorders
- Plant Molecular Biology Research
- Autism Spectrum Disorder Research
- MicroRNA in disease regulation
- Bone health and treatments
- Cocoa and Sweet Potato Agronomy
- Plant Gene Expression Analysis
- Chromosomal and Genetic Variations
- Connective tissue disorders research
- RNA Research and Splicing
- Powdery Mildew Fungal Diseases
- Complement system in diseases
- Plant and Fungal Interactions Research
- Signaling Pathways in Disease
- Autophagy in Disease and Therapy
- Virus-based gene therapy research
- Cerebral Palsy and Movement Disorders
- Bipolar Disorder and Treatment
- Genomics and Rare Diseases
Shandong Academy of Agricultural Sciences
2015-2025
Ministry of Agriculture and Rural Affairs
2025
Shandong University
2012-2025
State Key Laboratory of Microbial Technology
2025
Ocean University of China
2024
Qingdao National Laboratory for Marine Science and Technology
2024
Zhengzhou University
2018-2023
Zhengzhou Children's Hospital
2013-2023
Institute of Vegetables and Flowers
2017-2021
Biotechnology Research Center
2018
DNA methylation plays important roles in genome protection, regulation of gene expression and was associated with plants development. Plant pattern mediated by cytosine-5 methyltransferases demethylase. Although the genomes AA BB wild peanuts have been fully sequence, these two families not studied. In this study we report identification analysis putative (C5-MTases) demethylase peanuts. Cytosine-5 could be classified known MET, CMT DRM2 groups based on their domain organization. This result...
The basic/helix-loop-helix (bHLH) proteins constitute a superfamily of transcription factors that are known to play range regulatory roles in eukaryotes. Over the past few decades, many bHLH family genes have been well-characterized model plants, such as Arabidopsis, rice and tomato. However, protein peanuts has not yet systematically identified characterized. Here, 132 129 were from two wild ancestral diploid subgenomes cultivated tetraploid peanuts, Arachis duranensis (AA) ipaensis (BB),...
Abstract Background Long non-coding RNAs (lncRNAs) are a class of with more than 200 nucleotides in length, which play vital roles wide range biological processes. Powdery mildew disease (PM) has become major threat to the production melon. To investigate potential lncRNAs resisting PM melon, it is necessary identify and uncover their molecular functions. In this study, we compared between resistant susceptible melon response infection. Results It reported that 11,612 were discovered,...
Salt stress, as a significant adverse consequence of global climate change, severely restricts the yield and quality watermelon. In this study, salt-tolerant cultivar T23 salt-sensitive B2 were subjected to 200 mM NaCl treatment (0 h, 6 24 48 168 h) at three-leaf stage, adaptation mechanisms watermelon roots salt stress systematically investigated phenotypic, physiological, gene transcription levels. Phenotypic observations revealed that inhibited seedling growth, caused leaf curling,...
This study aimed to investigate the correlation between salt tolerance during germination and seedling stages in melons by analyzing 10 melon varieties under NaCl stress stages. We found that 200 mM is appropriate concentration for screening salt-tolerant germplasm melons. Salt led a decline growth parameters, while antioxidant enzyme activities osmotic substance contents significantly increased. Specifically, of CAT SOD increased up 27.22-fold 6.35-fold, respectively, soluble protein...
Peanut zygotes typically divide a few times to form pre-embryo before further embryonic development halts under normal day/night photoperiods. Ovary elongation, however, continuesforming downward growing peg-like structure. When the peg is buried in soil, embryo resumes darkness. The embryo-located region (ER) of begins enlarge and pod, while basal (BR) has distinct fate. molecular mechanisms governing these unique processes are unknown. In this study, histological analysis demonstrated that...
Objective: This study is to investigate the diagnostic yield of combination trio whole exome sequencing (Trio-WES) and copy number variation (CNVseq) for rare neurodevelopmental disorders (NDDs). Methods: Clinical data from consecutive paediatric patients who were diagnosed with NDDs that suspected be monogenic disorders, admitted our hospital Apr 2017 Mar 2019, underwent next generation (NGS) extracted medical records. Patients whom Trio-WES CNVseq available enrolled in this study. Sanger...
As a typical geocarpic plant, peanut embryogenesis and pod development are complex processes involving many gene regulatory pathways controlled by appropriate hormone level. MicroRNAs (miRNAs) small non-coding RNAs that play indispensable roles in post-transcriptional regulation. Recently, identification characterization of miRNAs has been described. However, whether participate the regulation yet to be explored. In this study, RNA degradome libraries from early different developmental...
The WRKY proteins constitute a large family of transcription factors that have been known to play wide range regulatory roles in multiple biological processes. Over the past few years, many reports focused on analysis evolution and function genes at whole genome level different plant species. However, little information is about melon (Cucumis melo L.). In present study, total 56 putative were identified melon, which randomly distributed their respective chromosomes. A sequence alignment...
Lithium is a widely used and effective treatment for individuals with psycho-neurological disorders, it exhibits protective regenerative properties in multiple brain injury animal models, but the clinical experience young children limited due to potential toxicity. As an interim analysis, this paper reports safety/tolerability profiles of low-dose lithium intellectual disability (ID) its possible beneficial effects. In randomized, single-center trial, 124 ID were given either oral carbonate...
Early peanut pod development is an important process of reproductive development. Modes DNA methylation during early are still unclear, possibly because its allotetraploid genome may cause difficulty for the methylome analysis.To investigate functions dynamic pod, global and gene expression analyses were carried out by Illumina high throughput sequencing. A novel mapping strategy reads was developed used analysis. Differentially methylated genes, such as nodulin, cell number regulator-like...
With experimental and bioinformatical methods, numerous small RNAs, including microRNAs (miRNAs) short interfering RNAs (siRNAs), have been found in plants, they play vital roles various biological regulation processes. However, most of these remain to be functionally characterized. Until now, only several viral vectors were developed overexpress miRNAs with limited application plants. In this study, we report a new RNA overexpression system via satellite DNA associated Tomato yellow leaf...
Circular RNAs (circRNAs) are a class of newly discovered non-coding that typically derived from genome’s exonic, intronic, and intergenic regions. Recent studies circRNAs in animals plants have shown vital response to various abiotic biotic stresses. Powdery mildew disease (PM) is serious fungal threatening the melon industry. We performed whole transcriptome sequencing using leaves PM-resistant (M1) PM-susceptible (B29) identify determine their molecular functions. A total 303 were...
SET is a multifunctional protein involved in regulating many biological processes of the cell cycle. It also regulator steroidogenesis ovary. However, expression testis, and its function, still remains ambiguous. In this study, we observed testes mice at different developmental stages, have discussed potential function spermatogenesis androgen production. Forty-eight male stages (1 week old as infancy group; 4 weeks prepubertal 12 adult over months ageing group) were used. Cellular location...
Long noncoding RNAs (lncRNAs) have been strongly associated with various types of cancer. The present study aimed at exploring the diagnostic and prognostic value lncRNA Zinc finger protein 667-antisense RNA 1 (ZNF667-AS1) in glioma patients. Patients Methods. expressions ZNF667-AS1 were detected 155 tissues matched normal brain tissue samples by qRT-PCR. receiver operating characteristic (ROC) curve was performed to estimate ZNF667-AS1. association between expression clinicopathological...
Abstract Protein phosphatase 1 regulatory subunit 3F (PPP1R3F) is a member of the glycogen targeting subunits (GTSs), which belong to large group protein (PP1), major eukaryotic serine/threonine that regulates diverse cellular processes. Here, we describe identification hemizygous variants in PPP1R3F associated with novel X-linked recessive neurodevelopmental disorder 13 unrelated individuals. This characterized by developmental delay, mild intellectual disability, neurobehavioral issues...
Orosomucoid 1‐Like Protein 3 ( ORMDL3 ) is an asthma candidate gene and Casitas B lineage lymphoma b (Cbl‐b), E3 ubiquitin ligase, a critical factor in maintaining airway immune tolerance. However, the association of Cbl‐b with for unclear. Here, we show that expression significantly increased shows strong linear correlation decreased peripheral blood recurrent wheeze patients. To elucidate molecular mechanisms underlying this correlation, identified suppressed transcriptional activity mRNA...
In this paper, we introduce a military boxing learning system implemented by 3D motion capture, Web3D and interactive technologies, which can support that users observe learn the details of each action under different views scales translating, rotating zooming human body models. Beside keyboards mice, smartphones also be used in system, provide some natural operations voice touch technologies. The extended to tai chi boxing, radio gymnastic exercises other routines actions.