A5015402412- Plant-Microbe Interactions and Immunity
- Plant Disease Resistance and Genetics
- Plant Molecular Biology Research
- Plant Stress Responses and Tolerance
- Legume Nitrogen Fixing Symbiosis
- Plant pathogens and resistance mechanisms
- Plant Pathogenic Bacteria Studies
- Plant Virus Research Studies
- Protease and Inhibitor Mechanisms
- Heavy Metal Exposure and Toxicity
- Rice Cultivation and Yield Improvement
- Fermentation and Sensory Analysis
- Plant Reproductive Biology
- Microbial Metabolism and Applications
- Biological and pharmacological studies of plants
- Cocoa and Sweet Potato Agronomy
- Wound Healing and Treatments
- Microbial infections and disease research
- Essential Oils and Antimicrobial Activity
- Lipid metabolism and disorders
- Plant Gene Expression Analysis
- Neurological Disease Mechanisms and Treatments
- Cardiovascular Health and Disease Prevention
- Genetic Syndromes and Imprinting
- Aldose Reductase and Taurine
Sichuan Agricultural University
2017-2024
First Affiliated Hospital of Xi'an Jiaotong University
2024
Mianyang Normal University
2024
Donghua University
2023
First Affiliated Hospital of Fujian Medical University
2022
Rice Research Institute
2017-2022
Fujian Medical University
2022
Chinese Academy of Sciences
1996-2016
Chengdu Institute of Biology
2016
Guangzhou University of Chinese Medicine
2015
miR169 is a conserved microRNA (miRNA) family involved in plant development and stress-induced responses. However, how functions rice immunity remains unclear. Here we show that acts as negative regulator against the blast fungus Magnaporthe oryzae by repressing expression of Nuclear Factor Y-A (NF-YA) genes. The accumulation was significantly increased susceptible accession but slightly fluctuated resistant upon M. infection. Consistently, transgenic lines overexpressing miR169a became...
Circular RNAs (circRNAs) play roles in various biological processes, but their functions the rice (Oryza sativa) response to Magnaporthe oryzae remain elusive. Here, we demonstrate that circRNAs are involved rice-M. interaction using comparative circRNA-sequencing and transgenic approaches. We identified 2932 high-confidence from young leaves of blast-resistant accession International Rice Blast Line Pyricularia-Kanto51-m-Tsuyuake (IR25) blast-susceptible Lijiangxin Tuan Heigu (LTH) under...
Grain formation is fundamental for crop yield but vulnerable to abiotic and biotic stresses. Rice grain production threatened by the false smut fungus Ustilaginoidea virens, which specifically infects rice floral organs, disrupting fertilization seed formation. However, little known about molecular mechanisms of U. virens–rice interaction genetic basis resistance. Here, we report that virens secretes a cytoplasmic effector, UvCBP1, facilitate infection flowers. Mechanistically, UvCBP1...
Abstract The flower-infecting fungus Ustilaginoidea virens causes rice false smut, which is a severe emerging disease threatening (Oryza sativa) production worldwide. False smut not only reduces yield, but more importantly produces toxins on grains, posing great threat to food safety. U. invades spikelets via the gap between 2 bracts (lemma and palea) enclosing floret specifically infects stamen pistil. Molecular mechanisms for virens–rice interaction are largely unknown. Here, we...
Summary Rice false smut has emerged as a serious grain disease in rice production worldwide. The is characterized by the transformation of individual florets into balls, which caused fungal pathogen Ustilaginoidea virens . To date, little known about host factors required for ball formation U In this study, we identified histological determinants balls inoculating floral mutants defective with respect to parts. results showed that could form mature pistils, but failed develop superwoman...
microRNAs act as fine-tuners in the regulation of plant growth and resistance against biotic abiotic stress. Here we demonstrate that rice miR1432 fine-tunes yield blast disease via different modules. Overexpression leads to compromised decreased yield, whereas blocking using a target mimic results enhanced yield. suppresses expression LOC_Os03g59790, which encodes an EF-hand family protein 1 (OsEFH1). OsEFH1 but grain Further study revealed are differentially responsive chitin,...
Rice production is threatened by multiple pathogens. Breeding cultivars with broad-spectrum disease resistance necessary to maintain and improve crop production. Previously we found that overexpression of miR160a enhanced rice blast resistance. However, it unclear whether also regulates against other pathogens, what the downstream signaling pathways are. Here, demonstrate positively causative agents blast, leaf blight sheath in rice. Mutations miR160a-targeted Auxin Response Factors result...
Magnaporthe oryzae is the causative agent of rice blast, a devastating disease in worldwide. Based on gene-for-gene paradigm, resistance (R) proteins can recognize their cognate avirulence (AVR) effectors to activate effector-triggered immunity. AVR genes have been demonstrated evolve rapidly, leading breakdown genes. Therefore, understanding variation essential deployment resistant cultivars harboring R In this study, we analyzed nucleotide sequence polymorphisms eight known genes, namely,...
As a continuation of our efforts directed towards the development natural anti-diabetic cataract agents, gigantol was isolated from Herba dendrobii and found to inhibit both aldose reductase (AR) inducible nitric oxide synthase (iNOS) activity, which play significant role in progression diabetic cataracts. To improve its bioefficacy facilitate use as therapeutic agent, (compound 14f) series novel analogs were designed synthesized. Analogs formulated have different substituents on phenyl ring...
Background: Citrus yellow vein-clearing virus (CYVCV) is a Mandarivirus that causes great economic losses in lemon production. CYVCV infection associated with obvious disease symptoms and directly regulated by plant hormone responses. Methods: To understand how plants respond to infection, we performed transcriptomic phytohormone metabolomics. Results: A total of 936 differentially expressed genes were identified, 773 downregulated. Salicylic acid auxin levels increased after regulatory...
False smut is a destructive grain disease of rice worldwide, characterized by false balls formed in flowers. Here we identified small secreted protein UV_1261 contributing to virulence Ustilaginoidea virens, the causal agent this disease. The sequence was highly conserved among isolates U. virens and absent other fungi. encodes targeted plant chloroplasts. Its expression exhibited bimodal pattern during pathogenesis. Ectopic Nicotiana benthamiana Arabidopsis led suppression flg22-induced ROS...
Ustilaginoidea virens is a biotrophic fungal pathogen specifically colonizing rice floral organ and causes false smut disease of rice. This has emerged as serious problem that hinders the application high-yield cultivars, by reducing grain yield quality well introducing mycotoxins. However, pathogenic mechanisms U. are still enigmatic. Here we demonstrate employs secreted protein UvCBP1 to manipulate plant immunity. In planta expression led compromised chitin-induced defense responses in...
This study aims to retrospectively evaluate the association between pericarotid inflammation and presence of embolic stroke undetermined source (ESUS).In total, 126 patients with ESUS 118 ischemic from large artery atherosclerosis (LAA) were enrolled. All underwent brain MRI a neck CT angiography (CTA) examination. Reviewers blinded infarct location cause. Paired t-tests assessed within-subjects differences in mean Hounsfield units (HUs) carotid perivascular fat cerebral infarction side...
Abstract Objectives To investigate the association of eight variants four matrix metalloproteinase (MMP) genes with ischemic stroke (IS) and whether interactions among these single nucleotide polymorphisms (SNPs) increases risk IS. Methods Among 547 patients 350 controls, matrix‐assisted laser desorption/ionization time flight mass spectrometry was used to examine arising from different genes, including MMP‐1 (rs1799750), MMP‐2 (rs243865, rs2285053, rs2241145), MMP‐9 (rs17576), MMP‐12...
Flower opening and stigma exertion are two critical traits for cross-pollination during seed production of hybrid rice (Oryza sativa L.). In this study, we demonstrate that the miR167d-ARFs module regulates size flower is associated with elongation stamen filaments cell arrangement lodicules. The overexpression miR167d (OX167d) resulted in failed filaments, increased size, morphological alteration lodicule, resulting cleistogamy. Blocking by target mimicry also led to a individual floral...
Summary Arabidopsis RESISTANCE TO POWDERY MILDEW 8.2 (RPW8.2) is specifically induced by the powdery mildew (PM) fungus ( Golovinomyces cichoracearum ) in infected epidermal cells to activate immunity. However, mechanism of RPW8.2‐induction not well understood. Here, we identify a G. effector that interacts with RPW8.2, named Gc‐RPW8.2 interacting protein 1 (GcR8IP1), yeast two‐hybrid screen an cDNA library. GcR8IP1 physically associated RPW8.2 its REALLY INTERESTING NEW GENE finger domain...
Rice blast, a prevalent and highly destructive rice disease that significantly impacts yield, is caused by the blast fungus. In present study, strain named MTC-8, identified as