A5055299145- Sinusitis and nasal conditions
- Head and Neck Surgical Oncology
- Salivary Gland Tumors Diagnosis and Treatment
- Peptidase Inhibition and Analysis
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Tracheal and airway disorders
- Biological and pharmacological studies of plants
- Lipid metabolism and disorders
- Infectious Diseases and Mycology
- Angiogenesis and VEGF in Cancer
- Cancer, Hypoxia, and Metabolism
- Bone Tumor Diagnosis and Treatments
- Allergic Rhinitis and Sensitization
- Oral and Maxillofacial Pathology
- Ginseng Biological Effects and Applications
- Pediatric health and respiratory diseases
- Antifungal resistance and susceptibility
- Systemic Lupus Erythematosus Research
- Mycobacterium research and diagnosis
- Phytochemistry and biological activity of medicinal plants
- Brain Metastases and Treatment
- Natural Antidiabetic Agents Studies
- COVID-19 and healthcare impacts
- Inhalation and Respiratory Drug Delivery
- Meningioma and schwannoma management
Zhejiang University
2011-2024
First Affiliated Hospital Zhejiang University
2005-2023
Tsinghua–Berkeley Shenzhen Institute
2022-2023
Shenzhen Bay Laboratory
2022-2023
Military Hospital
2023
Fujian Women and Children Hospital
2023
Children's Hospital
2023
Xiamen Chang Gung Hospital
2023
Zhongshan Hospital of Xiamen University
2023
174th hospital of the People's Liberation Army
2023
Diabetes and its complications are one of the most concerned metabolic diseases worldwide threaten human health severely. Hypoglycemic hypolipidemic effects glucomannan extracted from konjac on high-fat diet streptozocin-induced type 2 diabetic rats were evaluated in this study. Administration significantly decreased levels fasting blood glucose, serum insulin, glucagon-like peptide 1, glycated protein. The concentrations lipids, including total cholesterol, triacylglycerols, low-density...
Type 2 diabetes (T2D) is a worldwide epidemic associated with metabolic disorders and intestinal microbiota alterations. Polysaccharides have been considered to be beneficial the prevention alleviation of T2D. In present study, ultra-performance liquid chromatography–triple-time-of-flight-based metabolomics proteomics 16S rRNA sequencing methods were employed evaluate effects glucomannans from Dendrobium officinale stem, konjac, Aloe vera leaves on host metabolism regulation in type diabetic...
To investigate the spectrum, antibiotic-resistant pattern, risk factors, and outcomes of infection in patients hospitalized with systemic lupus erythematosus (SLE).We collected clinical microbiological data from SLE between June 2005 2015, then conducted retrospective analyses.Among our sample 3815 patients, 1321 (34.6%) were diagnosed infection. The majority (78.3%) occurred within 5 years onset. Bacterial was predominant (50.6%), followed by viral (36.4%) fungal (12.5%). lungs (33.7%)...
Scope This study is aimed to investigate the kidney protective effects of glucomannans from Dendrobium officinale stem, konjac, and Aloe vera leaves on type 2 diabetic rats explore its potential mechanisms. Methods results Pathological metabolomics analysis methods are adopted in this study. Compared with model group, lower levels fasting blood glucose, serum insulin, glycated protein observed glucomannan‐treated groups. Concentrations low‐density lipoprotein cholesterol, total...
Enhanced recovery after surgery (ERAS) has rapidly gained popularity among hip or knee arthroplasty area which can decrease hospital length of stay (LOS). However, limited data exist regarding its safety and efficacy intertrochanteric fracture patients. The purpose this study was to determine if LOS associated with patients be improved following an existing orthopedic ERAS procedure.We reviewed the outcomes all who had been treated PFNA intramedullary fixation at our institution. Open...
Obesity is a major public health concern that has almost reached the level of pandemic and rapidly progressing. The gut microbiota emerged as crucial regulator involved in etiology obesity, manipulation it by dietary intervention been widely used for reducing risk obesity. Nondigestible oligosaccharides (NDOs) are attracting increasing interests prebiotics, indigestible ingredients can induce compositional or metabolic improvement to microbiota, thereby improving giving rise production...
Gamma-Aminobutyric acid (GABA) could regulate physiological functions in the gastrointestinal tract. The present study aimed to investigate effect of GABA on colon health mice. female Kunming mice were given at doses 5, 10, 20 and 40 mg/kg/d for 14 days. Afterwards, short-chain fatty acids (SCFAs) concentrations, pH values, index, length weight colonic cecal contents determined evaluate effects health. results showed that intake increase concentrations acetate, propionate, butyrate total...
Background: The hemoglobin glycation index (HGI) has been proposed as a marker to quantify inter-individual variation in glycosylation. However, whether HGI is associated with an increased risk of diabetic complications independent glycated (HbA1c) remains unclear. This meta-analysis aimed determine the association between and all cause mortality composite cardiovascular disease (CVD). Methods: PubMed, EMBASE databases were searched for related studies up March 31, 2021. Observational...
The mining of antidiabetic dipeptidyl peptidase IV (DPP-IV) inhibitory peptides (DPP-IV-IPs) is currently a costly and laborious process. Due to the absence rational peptide design rules, it relies on cumbersome screening unknown enzyme hydrolysates. Here, we present an enhanced deep learning model called bidirectional encoder representation (BERT)-DPPIV, specifically designed classify DPP-IV-IPs explore their rules discover potent candidates. end-to-end utilizes fine-tuned BERT architecture...
A retrospective study was performed to investigate the clinical features and associated factors of invasive mycoses (IM) in patients with connective tissue disease (CTD) from Southern China. Demographic data were recorded. Associated analyzed by logistic regression analysis. total 6911 CTD included. IM diagnosed 32 (incidence, 0.5%). predominant ANCA-associated vasculitis (AAV) 1.5%, 7/480). Lung commonly involved (30/32, 93.8%). Aspergillus spp. (81.3%) leading strain. The positive rate...
Hyperuricemia (HUA) is a vital risk factor for chronic kidney diseases (CKD) and development of functional foods capable protecting CKD importance. This paper aimed to explore the amelioration effects mechanism <em>Andrias davidianus</em> bone peptides (ADBP) on HUA-induced damage. In present study, we generated standard ADBP which contained high hydrophobic amino acid low molecular peptide contents. <em>In vitro</em> results found that protected uric (UA)-induced HK-2 cells from damage by...