A5015885592- Liver Disease Diagnosis and Treatment
- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Cancer-related molecular mechanisms research
- Estrogen and related hormone effects
- Liver physiology and pathology
- Genetic factors in colorectal cancer
- Cholangiocarcinoma and Gallbladder Cancer Studies
- RNA modifications and cancer
- Cognitive Radio Networks and Spectrum Sensing
- Cancer-related gene regulation
- Cancer Genomics and Diagnostics
- Cancer Immunotherapy and Biomarkers
- Sepsis Diagnosis and Treatment
- Circular RNAs in diseases
- Bone Tumor Diagnosis and Treatments
- Lymphatic System and Diseases
- Cardiac Health and Mental Health
- Fire effects on ecosystems
- Distributed Sensor Networks and Detection Algorithms
- Data-Driven Disease Surveillance
- Viral-associated cancers and disorders
- Fungal Infections and Studies
- Ultrasound and Hyperthermia Applications
- Sarcoma Diagnosis and Treatment
Zhejiang University
2025
Sir Run Run Shaw Hospital
2025
The Affiliated Yongchuan Hospital of Chongqing Medical University
2024-2025
Chongqing Medical University
2024-2025
Yangtze University
2020-2025
Guangdong Medical College
2020-2025
Baotou Medical College
2024
First Affiliated Hospital of GuangXi Medical University
2018-2024
Guangxi Medical University
2018-2024
Harbin Medical University
2017-2024
The inflammatory response of macrophages has been reported to play a critical role in atherosclerosis. state is modified by epigenetic reprogramming. m6A RNA methylation an modification RNAs. However, little known about the potential roles and underlying mechanisms macrophage inflammation. Herein, we showed that expression "writer" Mettl14 was increased coronary heart disease LPS-stimulated THP-1 cells. Knockdown promoted M2 polarization macrophages, inhibited foam cell formation decreased...
To maintain mitochondrial homeostasis, damaged or excessive mitochondria are culled in coordination with the physiological state of cell. The integrated stress response (ISR) is a signaling network that recognizes diverse cellular stresses, including dysfunction. Because four ISR branches converge to common outputs, it unclear whether detected by this can regulate mitophagy, autophagic degradation mitochondria. Using whole-genome screen, we show heme-regulated inhibitor (HRI) branch...
Coronavirus disease 2019 (COVID-19) can lead to serious illness and death, thus, it is particularly important predict the severity prognosis of COVID-19. The Sequential Organ Failure Assessment (SOFA) score has been used clinical outcomes patients with multiple organ failure requiring intensive care. Therefore, we retrospectively analyzed characteristics, risk factors, relationship between SOFA COVID-19 patients.We included all ≥18 years old who were diagnosed in laboratory continuously...
Abstract Metabolic dysfunction-associated steatotic liver disease (MASLD) has emerged as a predominant worldwide, lacking approved drugs for clinical intervention at present. The composite dietary antioxidant index (CDAI) is used to assess the anti-inflammatory properties of diets, with higher CDAI indicating greater exposure antioxidants. Therefore, our study aimed explore relationship between and MASLD in order identify potential therapeutic approaches. We collected data from 12,286...
Abstract Since the emergence of SARS-CoV-2, numerous studies have been attempting to determine biomarkers, which could rapidly and efficiently predict COVID-19 severity, however there is lack consensus on a specific one. This retrospective cohort study comprehensive analysis initial symptoms, comorbidities laboratory evaluation patients, diagnosed with in Huoshenshan Hospital, Wuhan, from 4th February 12th March, 2020. Based data collected 63 severely ill patients onset symptoms till full...
Metabolic associated fatty liver disease (MAFLD) has become the most common globally, yet no new drugs have been approved for clinical treatment. Therefore, we investigated relationship between dietary intake of soy-derived daidzein and MAFLD, to find potentially effective treatments. We conducted a cross-sectional study using data from 1,476 participants in National Health Nutrition Examination Survey (NHANES) 2017 2018 their flavonoid database USDA Food Nutrient Database Dietary Studies...
With the continuous advancement of global informatization, way enterprise financial management under big data environment is undergoing profound changes. This paper takes NIO as research object to explore how prevent risks in context data. Firstly, definition and its specific application are studied reveal supportive role technology collection, analysis decision-making information. Second, this provides a detailed categorization help identify potential problems. Through in-depth NIO's data,...
Abstract Intervertebral disc degeneration (IVDD) is a leading cause of low back pain, with limited effective treatments due to an incomplete understanding disease mechanisms. In this study, we report that circFUNDC1, nuclear circular RNA, markedly downregulated in nucleus pulposus cells (NPCs) from patients end-stage IVDD. CircFUNDC1 derived the gene encoding FUN14 domain-containing 1 (FUNDC1) protein, which essential for mitophagy and cell survival. Functional analyses reveal circFUNDC1...
The aging of China is deepening year by year, and improving the quality dying death (QODD) increasingly becoming an urgent realistic need. This study explores gender differences in its influencing factors among Chinese older adults, aiming to provide assistance relevant authorities formulating end-of-life care policies for adapt needs society. Based on data Longitudinal Health Longevity Survey (CLHLS) during 2008-2018, a total 7,341 respondents were included. Chi-square test logistic...
predictive model for distinguishing intrahepatic cholangiocarcinoma (ICC) from hepatocellular carcinoma (HCC) in high-risk patients. METHODSThis retrospective study consisted of 88 consecutive patients with ICC and HCC selected by propensity score matching between May 2004 July 2016.Patients were assigned to two groups, namely, a training set validation set, at 1:1 ratio.A CEUS diagnosing was generated based on significant features.Then, nomogram the developed, integrating clinical data.The...
The aim of the current study was to evaluate protective effects and mechanisms isoliquiritigenin (ISO) on acute renal injury. CCK-8 assays were applied assess ISO at different doses (20, 40, 80 μg/mL) oxidative damage in human HK-2 cells incubated with high glucose. After diabetic nephropathy (DN) rat model established, animals randomly assigned saline-treated control, three groups received 10, 20 40 mg/kg ISO, respectively, using healthy Sprague-Dawley (SD) rats as normal control. blood...
Three isonitrogenous diets (41% crude protein) with 4.87%, 10.75% and 16.10% lipid were designed to evaluate the effects of dietary levels growth, antioxidant capacity, expression genes related glucose metabolism juvenile Scylla paramamosain. Each diet was fed four replicates 32 crabs initial weight 5.10 ± 0.05 g for 6 weeks. The results indicated that exhibited significantly higher percent gain (PWG) specific growth rate (SGR) than those 4.87% (P < 0.05), had protein efficiency ratio (PER)...
Background: The noninvasive computed tomography angiography–derived fractional flow reserve (CT-FFR) can be used to diagnose coronary ischemia. With advancements in associated software, the diagnostic capability of CT-FFR may have evolved. This study evaluates effectiveness a novel deep learning-based software predicting ischemia through CT-FFR. Methods: In this prospective study, 138 subjects with suspected or confirmed artery disease were assessed. Following indication 30%–90% stenosis on...
To investigate the characteristics and associated factors of invasive fungal disease in patients with systemic lupus erythematosus from Southern China.A retrospective study was performed. Demographic clinical characteristics, laboratory data, radiographic manifestations were recorded.A total 45 (incidence 1.1%) included. Twenty-three cases (51.1%) infected mold 22 (48.9%) yeast. Aspergillus spp. (44.4%) Cryptococcus (33.3%) common. Aspergillosis mainly occurred lung. Cryptococcosis developed...
// Yunping Pan 1, 2, * , Xu Guo 3, Zheng Yang 2 ,* Shan Chen 1 Yiyan Lei 4 Millicent Lin 5 Liantang Wang Chongjin Feng Zunfu Ke Department of Stomatology, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, Province Guangdong, P.R.China Pathology, 3 Gynecology, P.R. China Chest Surgery, Molecular and Medical Pharmacology, Crump Institute for Imaging (CIMI), California NanoSystems (CNSI), University California, Los Angeles, USA These authors have contributed equally to...
Recent observations revealed Foxp3 participated in the development of cervical cancer. Furthermore, has a vital function lymphatic metastasis However, it is unclear whether correlated with lymphangiogenesis In this experiment, expression and VEGF-C was detected 50 cancer samples by immunohistochemistry. addition, we evaluated association between vessel density. These data demonstrate positively expression. associated results play an important role Gunagdong Medical University, PJ2013049