Hellen Tukamuhebwa Aanyu

ORCID: 0000-0003-3159-4318
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About
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Research Areas
  • COVID-19 Clinical Research Studies
  • COVID-19 Impact on Reproduction
  • Tuberculosis Research and Epidemiology
  • Child Nutrition and Water Access
  • Kawasaki Disease and Coronary Complications
  • Global Maternal and Child Health
  • COVID-19 diagnosis using AI
  • Artificial Intelligence in Healthcare and Education
  • Healthcare Systems and Reforms
  • Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
  • Viral gastroenteritis research and epidemiology
  • Parasites and Host Interactions
  • Disaster Response and Management
  • Parasitic Diseases Research and Treatment
  • Pharmacological Receptor Mechanisms and Effects
  • Hemoglobinopathies and Related Disorders
  • Adolescent and Pediatric Healthcare
  • Tryptophan and brain disorders
  • Lysosomal Storage Disorders Research
  • Sepsis Diagnosis and Treatment
  • Asthma and respiratory diseases
  • Vaccine Coverage and Hesitancy
  • Viral Infections and Outbreaks Research
  • Respiratory Support and Mechanisms
  • Iron Metabolism and Disorders

Mulago Hospital
2013-2025

Global Forum for Health Research
2022

Makerere University
2013-2018

Jean B. Nachega Nadia A. Sam‐Agudu Rhoderick Machekano Helena Rabie Marieke M. van der Zalm and 95 more Andrew Redfern Angela Dramowski Natasha O’Connell Michel Tshiasuma Pipo Marc Tshilanda Liliane N. Byamungu Refiloe Masekela Prakash Jeena Ashendri Pillay Onesmus Gachuno John Kinuthia Daniel Katuashi Ishoso Emmanuella Amoako Elizabeth Agyare Evans Kofi Agbeno Charles Martyn‐Dickens Justice Sylverken Anthony Enimil Aishatu Mohammed Jibril Asara M. Abdullahi Oma Amadi Umar Mohammed Umar Lovemore Nyasha Sigwadhi Michel P. Hermans John Otshudiema Otokoye Placide Mbala‐Kingebeni Jean‐Jacques Muyembé‐Tamfum Alimuddin Zumla Nelson Sewankambo Hellen Tukamuhebwa Aanyu Philippa Musoke Fátima Suleman Prisca Olabisi Adejumo Emília Virginia Noormahomed Richard J. Deckelbaum Mary Glenn Fowler Léon Tshilolo Gerald E. Smith Edward J. Mills Lawal Umar Mark J. Siedner Mariana Kruger Philip J. Rosenthal John W. Mellors Lynne Mofenson Jean B. Nachega Nadia A. Sam‐Agudu Rhoderick Machekano Helena Rabie Marieke M. van der Zalm Andrew Redfern Angela Dramowski Natasha O’Connell Michel Tshiasuma Pipo Marc Tshilanda Liliane N. Byamungu Refiloe Masekela Prakash Jeena Ashendri Pillay Onesmus Gachuno John Kinuthia Daniel Katuashi Ishoso Emmanuella Amoako Elizabeth Agyare Evans Kofi Agbeno Charles Martyn‐Dickens Justice Sylverken Anthony Enimil Aishatu Mohammed Jibril Asara M. Abdullahi Oma Amadi Umar M. Umar Lovemore Nyasha Sigwadhi Michel P. Hermans John Otshudiema Otokoye Placide Mbala‐Kingebeni Alimuddin Zumla Hellen Tukamuhebwa Aanyu Philippa Musoke Fátima Suleman Emília Virginia Noormahomed Mary Glenn Fowler Léon Tshilolo Mariana Kruger Gerald E. Smith Philip J. Rosenthal Edward J. Mills Lawal Umar John W. Mellors Prisca Olabisi Adejumo Nelson Sewankambo Mark J. Siedner Richard J. Deckelbaum Jean‐Jacques Muyembé‐Tamfum Lynne Mofenson

Little is known about COVID-19 outcomes among children and adolescents in sub-Saharan Africa, where preexisting comorbidities are prevalent.To assess the clinical factors associated with hospitalized 6 countries Africa.This cohort study was a retrospective record review of data from 25 hospitals Democratic Republic Congo, Ghana, Kenya, Nigeria, South Uganda March 1 to December 31, 2020, included 469 patients aged 0 19 years SARS-CoV-2 infection.Age, sex, comorbidities, region residence.An...

10.1001/jamapediatrics.2021.6436 article EN cc-by JAMA Pediatrics 2022-01-19

Nodding syndrome is a devastating neurological disorder of uncertain aetiology affecting children in Africa. There no diagnostic test, and risk factors symptoms that would allow early diagnosis are poorly documented. This study aimed to describe the clinical, electrophysiological brain imaging (MRI) features complications nodding Ugandan children.Case series.22 with brought Mulago National Referral Hospital for assessment.Clinical features, physical functional disabilities, EEG MRI findings...

10.1136/bmjopen-2012-002540 article EN cc-by-nc BMJ Open 2013-01-01

Abstract Prior research suggests that fluvoxamine, a selective serotonin reuptake inhibitor (SSRI) used for the treatment of obsessive-compulsive disorder and major depressive disorder, could be repurposed against COVID-19. We undertook prospective interventional open-label cohort study to evaluate efficacy tolerability fluvoxamine among inpatients with laboratory-confirmed COVID-19 in Uganda. The main outcome was all-cause mortality. Secondary outcomes were hospital discharge complete...

10.1038/s41380-023-02004-3 article EN cc-by Molecular Psychiatry 2023-03-03

Globally, there are prevailing knowledge gaps in the epidemiology, clinical manifestations, and outcomes of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection among children adolescents; these especially wide African countries. The availability robust age-disaggregated data is a critical first step improving on disease burden manifestations 2019 (COVID-19) children. Furthermore, it essential to improve understanding SARS-CoV-2 interactions with comorbidities coinfections...

10.1093/cid/ciab142 article EN other-oa Clinical Infectious Diseases 2021-02-10

Pulmonary complications are common among children with sickle cell disease (SCD). However, there is little literature on associated lung function abnormalities in Uganda. We aimed to determine the prevalence, patterns, and factors abnormal SCD a tertiary care hospital

10.1186/s12887-024-04988-5 article EN cc-by-nc-nd BMC Pediatrics 2024-08-10

Background Globally, pneumonia is the leading infectious cause of under-five mortality, and this can be reduced by prompt healthcare seeking. Data on factors associated with delays in seeking care for children Uganda scarce. Objectives The study aimed to determine prevalence, delay, barriers, facilitators under five years age severe attending Mulago National Referral Hospital (MNRH) Uganda. Methods A mixed methods cross-sectional was conducted among 384 caregivers at MNRH. Quantitative data...

10.1371/journal.pone.0291387 article EN cc-by PLoS ONE 2023-10-10

SARS-CoV-2-associated Multisystem Inflammatory Syndrome in children (MIS-C) has been described developed settings that have reported a high burden of COVID-19 cases. However, to date, there are few published cases MIS-C the African region. morbidity and even mortality without prompt diagnosis. We report case 9-year-old girl who presented with typical clinical features Uganda but had delay This aims raise awareness among health providers similar improve suspicion MIS-C, facilitate diagnosis...

10.1155/2022/7811891 article EN cc-by Case Reports in Infectious Diseases 2022-02-23

Diagnosing childhood pulmonary tuberculosis (TB) is a challenge, and this led the Uganda National Tuberculosis Leprosy Program (NTLP) to develop clinical treatment decision algorithm (TDA) for children. However, there limited data on its accuracy how it compares new World Health Organization (WHO) TB TDAs This study aimed evaluate compare of 2017 NTLP with 2022 WHO among children in Kampala, Uganda. We retrospectively assessed <15 years old who underwent an evaluation between November...

10.1101/2024.11.20.24317633 preprint EN cc-by medRxiv (Cold Spring Harbor Laboratory) 2024-11-21

Background: As COVID-19 disease surges across much of the world, researchers in different settings have a unique opportunity to address various research priorities that been identified. The challenges containment and mitigation strategies present for research, especially resource limited settings, could be significant negatively impact essential contribution these research.
 Objectives: To describe experiences conducting during this pandemic, discuss faced implemented challenges
...

10.24018/clinicmed.2021.2.1.9 article EN other-oa European Journal of Clinical Medicine 2021-01-08
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