A5048275057- Digital Media Forensic Detection
- Advanced Steganography and Watermarking Techniques
- Generative Adversarial Networks and Image Synthesis
- Fetal and Pediatric Neurological Disorders
- Image Processing Techniques and Applications
- Genomics and Rare Diseases
- Genomic variations and chromosomal abnormalities
- Genetics and Neurodevelopmental Disorders
- Extracellular vesicles in disease
- Polysaccharides and Plant Cell Walls
- Prenatal Screening and Diagnostics
- Anomaly Detection Techniques and Applications
- MicroRNA in disease regulation
- Health disparities and outcomes
- Epigenetics and DNA Methylation
- Circular RNAs in diseases
- Digestive system and related health
- Image and Video Quality Assessment
- Wireless Sensor Networks and IoT
- Adolescent and Pediatric Healthcare
- Advanced Image Processing Techniques
- Regional Economic and Spatial Analysis
- Advanced Neuroimaging Techniques and Applications
- Space Satellite Systems and Control
- Medical and Agricultural Research Studies
Harbin Medical University
2022-2025
Jilin Agricultural Science and Technology University
2023
Zunyi Medical University
2021-2023
BGI Group (China)
2019-2022
Dalian University of Technology
2022
Shanghai University
2021
China National GeneBank
2020
New Jersey Institute of Technology
2009-2019
Chinese Academy of Fishery Sciences
2019
Ministry of Agriculture and Rural Affairs
2019
Neurodegenerative diseases encompass a wide variety of pathological conditions caused by loss neurons in the central nervous system (CNS) and are severely debilitating. Exosome contains bio-signatures great diagnostic therapeutic value. There is proof that exosomal proteins can be biomarkers for Alzheimer's disease (AD) Parkinson's (PD). MicroRNAs exosome has potential to an important source neurodegenerative diseases. Here, we report microRNA performance human plasma small RNA sequencing. A...
The aim of this study is to evaluate the diagnostic value genome sequencing in children with epilepsy, and provide sequencing-based insights into molecular genetic mechanisms epilepsy help establish accurate diagnoses, design appropriate treatments assist counselling. We performed on 320 Chinese interpreted single-nucleotide variants copy number all samples. complete pedigree clinical data probands were established followed up. phenotypes, treatments, prognoses genotypes patients analysed....
Abstract Background The co-occurrence of diabetes and mental disorders is an exceedingly common comorbidity with poor prognosis. We aim to investigate the impact green space, garden natural environment on risk among population living diabetes. Methods performed a longitudinal analysis based 39,397 participants from UK Biobank. Residential space modeled land use data Land Cover Map were assigned residential address for each participant. Cox proportional hazards model was used analyze...
This study aims to estimate the global prevalence rate and disease burden of zinc deficiency from 1990 2020 in children under 5 years old. Using data WHO Global Database on Child Growth Malnutrition Burden Diseases, Injuries, Risk Factors Study, we analysed prevalence, disability-adjusted life (DALYs), deaths attributable by sex across 204 countries territories worldwide 2020. Globally, decreased 40 22% The age-standardised DALY 24.885 3.858 per 100,000 population 2019. Overall, its...
Abstract Structural anomalies of the central nervous system (CNS) are one most common fetal found during prenatal imaging. However, genomic architecture imaging phenotypes has not yet been systematically studied in a large cohort. Patients diagnosed with CNS were identified from medical records and images. Fetal samples subjected to low-pass deep whole-genome sequencing (WGS) for aneuploid, copy number variation (CNV), single-nucleotide variant (SNV, including insertions/deletions (indels)),...
Multiple-compression detection is of particular importance in video forensics, as it reveals possible manipulations to the content. However, methods for detecting multiple compressions with same quantisation parameters (QPs) are rarely reported. To deal this issue, a novel method presented study detect H.264/advanced coding QPs. First, new set, named ratio difference set (RDS), proposed, which calculated by identifying quantised DCT coefficients whose values will be changed after...
This study was conducted with the primary objective of assessing performance cfDNA methylation in detection colorectal cancer (CRC). Five tumor tissue, 20 peripheral blood leucocyte, and 169 samples were collected for whole-genome bisulfite sequencing (WGBS) analysis. Bioinformatic analysis to identify differentially methylated regions (DMRs) their functional characteristics. Quantitative methylation-specific PCR (qMSP) used validate levels DMRs tissues leucocytes. from CRC patients healthy...
Modified citrus pectin (MCP), a commercially available dietary supplement prepared from pectin, contains several different polysaccharide domains, but its primary chemical structure and the binding epitopes that antagonize galectin-3 function remain unclear. In this study, five fractions were isolated MCP after endo-polygalacturonase degradation (EMCP) combination of DEAE-cellulose Sepharose CL-6B or Sephadex G-75 chromatography. Their structures, abilities to inhibit galectin-3-mediated...
As considered to be less risky, expensive, and more convenient than radiological examinations, ultrasound has been routinely employed in prenatal exams for the past decades. However, quality of acquired samples, i.e., images or videos, further diagnosis is crucially depended on sonographer. At meantime, there are an extremely limited number experienced sonographer available fetal screening. Therefore, reduce workload sonographers, promote screening, a deep convolutional neural network based...
<title>Abstract</title> With the rapid development of artificial intelligence technology, more and deep-faked audios have emerged in cyberspace, leading to an urgent need for detecting tracing deep fake audios. Watermarking provides active method audios, especially through multi-bit watermarking technology. Multiple watermarks can provide stronger protection tracking capabilities various scenarios. Especially users upload that incorporate with both personal lyricist composer platform...
Abstract Introduction Thalassemia is one of the most common autosomal recessive inherited diseases worldwide, and it also highly prevalent variable in southern China. Various types genetic testing technologies have been developed for diagnosis screening thalassemia. Characterized genomic DNA reference materials (RMs) are necessary assay development, validation, proficiency testing, quality assurance. However, there no publicly available RMs thalassemia as yet. Methods To address need...
Ventriculomegaly (VM) is the medical term used to describe enlargement of lateral ventricles a level 10 mm or more, which most frequent sign possible CNS abnormality detected on prenatal ultrasound. In this paper, we aim evaluate feasibility CNN-based DL algorithms predicting fetal ventricular width from ultrasound images. The data was collected 626 pregnant women with gestational age between 22 26 weeks. 3456 brain images were picked out all 49222 stored freeze-frame 2304 transventricular...