A5013155931- Metabolomics and Mass Spectrometry Studies
- Cancer, Hypoxia, and Metabolism
- Trace Elements in Health
- Thermochemical Biomass Conversion Processes
- Nutritional Studies and Diet
- Gut microbiota and health
- Edible Oils Quality and Analysis
- Metabolism, Diabetes, and Cancer
- Vitamin D Research Studies
- Alcohol Consumption and Health Effects
- Cancer, Lipids, and Metabolism
- Diet and metabolism studies
- Genetic Mapping and Diversity in Plants and Animals
- Electrochemical sensors and biosensors
- Catalysis and Hydrodesulfurization Studies
- Advanced Chemical Sensor Technologies
- Catalysts for Methane Reforming
- Adipose Tissue and Metabolism
- Maritime Navigation and Safety
- Iron Metabolism and Disorders
- Coal and Its By-products
- Alzheimer's disease research and treatments
- Bone health and osteoporosis research
- Analytical Chemistry and Sensors
- Advanced biosensing and bioanalysis techniques
Harbin Medical University
2015-2025
China National Nuclear Corporation
2024
Second Affiliated Hospital of Harbin Medical University
2024
Beijing Forestry University
2023
Ministry of Agriculture and Rural Affairs
2023
Chongqing Three Gorges University
2020-2023
Yonker Environmental Protection (China)
2022
China Electric Power Research Institute
2021
North China Electric Power University
2021
Chongqing University of Technology
2018
Success of modern agriculture relies heavily on breeding crops with maximal regional adaptability and yield potentials. A major limiting factor for crop cultivation is their flowering time, which strongly regulated by day length (photoperiod) temperature. Here we report identification characterization Days to heading 7 (DTH7), a genetic locus underlying photoperiod sensitivity grain in rice. Map-based cloning reveals that DTH7 encodes pseudo-response regulator protein its expression...
Abstract Objective To estimate the global burden of type 2 diabetes in adolescents and young adults (aged 15-39 years) from 1990 to 2019. Design Systematic analysis. Data source Global Burden Disease Study Participants aged years 204 countries territories, 1990-2019. Main outcomes measures Age standardised incidence rate, age disability adjusted life (DALY) mortality rate for people 2019, proportional DALY attributable different risk factors. Results From significant increases were found...
<h3>Background:</h3> Early detection and diagnosis are very important for autism. Current of autism relies mainly on some observational questionnaires interview tools that may involve a great variability. We performed metabolomics analysis serum to identify potential biomarkers the early clinical evaluation <h3>Methods:</h3> analyzed discovery cohort patients with participants without in Chinese Han population using ultra-performance liquid chromatography quadrupole time-of-flight tandem...
Developing adequate ship domain models may significantly benefit vessel navigation safety. In essence, safety is collectively affected by the navigable waterway condition, size and shape of ship, operators' skills. The existing domains mainly use constant values for model input parameters, making them incapable handling site-specific conditions. This study proposes dynamic that take into consideration conditions, behaviours, types sizes, skills in a holistic manner. Specifically, conditions...
Abstract Background Lipoprotein lipase (LPL) and serum 25-hydroxyvitamin D [25(OH)D] play important roles in the regulation of lipid metabolism. Although dyslipidemia is associated with insulin resistance (IR) type 2 diabetes (T2D), there are limited data available regarding relationship LPL 25(OH)D to IR T2D at a population level. The objective present study investigate associations Chinese population. Methods cohort consisted 2708 subjects (1326 males, 1382 females; mean age 48.5 ± 12.6...
Alzheimer disease (AD) can be diagnosed by clinical and neuropsychologic tests at autopsy, but there are no simple effective diagnostic methods for detecting biomarkers in patients early stages of cognitive impairment. Early metabolic alterations that may facilitate AD diagnosis have not been thoroughly explored. We applied a nontargeted metabonomic approach using ultrahigh-performance liquid chromatography-quadrupole time-of-flight mass spectrometry to analyze serum urine samples from 46...
Enrichment and quantification of sugar phosphates (SPx) in biological samples were great significance medicine. In this work, a series zirconium-based metal-organic frameworks (MOFs) with different degrees defects, namely, HP-UiO-66-NH
BACKGROUND Isolated postchallenge diabetes (IPD), a subtype of type 2 mellitus (T2DM) defined as 2-h postprandial plasma glucose ≥200 mg/dL (≥11.1 mmol/L) and fasting (FPG) &lt;108 (&lt;6.0 mmol/L), is often overlooked during screening for on the basis FPG concentrations. A key challenge early identification IPD by use serum, which critical large-scale screening. METHODS We applied nontargeted metabolomic approach using ultra-high-performance liquid chromatography–quadrupole TOF–mass...
Abstract Heading date is a key trait in rice domestication and adaption, number of quantitative loci (QTLs) have been identified. The ( Oryza sativa L.) cultivars the Heilongjiang Province, northernmost region China, to flower extremely early fulfill their life cycle. However, critical genes or different gene combinations controlling flowering this not determined. QTL candidate analysis revealed that Hd2/Ghd7.1 / OsPRR37 plays major role distribution Heilongjiang. Further association with...
ABSTRACT To explore the effect of refining process on compounds soybean oil, three different refined grade oils were detected by ultra performance liquid chromatography‐high‐definition mass spectrometry and chemometrics for finding differential compounds. The results PCA PLS‐DA showed that had clear separation trend number content in crude oil (SCO) gradually reduced with increased refining. Our result indicated processes SCO. decreased trans fatty acids other unfavorable quality (free...
Alzheimer's disease (AD) is an aging-related neurodegenerative disease. We aimed to investigate the metabolic mechanisms of aging and AD identify potential biomarkers for early screening in a natural population. To analyze plasma metabolites related aging, we conducted untargeted metabolomics analysis using ultra-high-performance liquid chromatography/quadrupole time-of-flight mass spectrometry two-stage cross-sectional study. Spearman's correlation random forest were applied model...
Abstract Background Calcium deficiency is a global public-health problem. Although the initial stage of calcium can lead to metabolic alterations or potential pathological changes, difficult diagnose accurately. Moreover, details molecular mechanism remain somewhat elusive. To accurately assess and provide appropriate nutritional intervention, we carried out analysis in response deficiency. Methods The associated with were first investigated rat model, using urinary metabonomics based on...
Fatty acid amides (FAAs) are endogenous lipid molecules that exhibit various physiological activities. FAAs usually present at nanomolar levels in biological samples. In this study, a method for the qualitative and quantitative determination of six (linoleamide, linoleoyl ethanolamide, oleoyl palmitic amide, oleamide, octadecanamide) edible vegetable oils was established. All were detected sesame, peanut, soybean (decolorized non-decolorized), blended oils; five sunflower oil; four rice...
Deciphering the intrinsic molecular logic of empirical crop breeding from a genomic perspective is decisive prerequisite for breeding-by-design (BbD), but remains not well established. Here, we decoded historical features past rice by phenotyping and haplotyping 546 accessions covering majority cultivars bred in history Northeast China (NEC). We revealed that three groups founded genetic diversities NEC with distinct evolution patterns traced verified footprints to known or genome-wide...