A5101776894- Nanoparticle-Based Drug Delivery
- Graphene and Nanomaterials Applications
- MicroRNA in disease regulation
- Renal and related cancers
- Cancer Cells and Metastasis
- Characterization and Applications of Magnetic Nanoparticles
- Neonatal and fetal brain pathology
- Medical Imaging and Analysis
- Nanoplatforms for cancer theranostics
- Metabolomics and Mass Spectrometry Studies
- Essential Oils and Antimicrobial Activity
- Chronic Myeloid Leukemia Treatments
- Traditional Chinese Medicine Analysis
- Metabolism and Genetic Disorders
- Acute Myeloid Leukemia Research
- Cancer Mechanisms and Therapy
- Microfluidic and Bio-sensing Technologies
- Pancreatic and Hepatic Oncology Research
- Cytokine Signaling Pathways and Interactions
- Cerebrovascular and Carotid Artery Diseases
- Ferroptosis and cancer prognosis
- Lung Cancer Treatments and Mutations
- Neonatal Respiratory Health Research
- Cardiac Arrest and Resuscitation
- Anesthesia and Neurotoxicity Research
Xuzhou Medical College
2016-2025
Xuzhou Central Hospital
2019-2025
Ministry of Education of the People's Republic of China
2021-2024
Northwest University
2021-2024
Nanjing Medical University
2010-2020
Chongqing Medical University
2016
Nantong University
2011-2013
Affiliated Hospital of Nantong University
2011-2013
Nanjing Maternity and Child Health Care Hospital
2010
Cerebral ischemia-reperfusion (IR) injury is a frequent complication of ischemic stroke with the adverse impact on clinical prognosis. This study focused molecular mechanism associated TEA domain transcription factor 1 (TEAD1) and matrix metalloproteinase 3 (MMP3) in cerebral IR. In vitro, IR model was established using oxygen-glucose deprivation/reoxygenation (OGD/R) human brain microvascular endothelial cells (HBMVECs). TEAD1 MMP3 mRNA protein examination were performed by RT-qPCR western...
Normal implantation depends on appropriate trophoblast growth and invasion. Inadequate invasion results in pregnancy-related disorders, such as early miscarriage pre-eclampsia, which are dangerous to both the mother fetus. Msh Homeobox 2 (MSX2), a member of MSX family homeobox proteins, plays significant role proliferation differentiation various cells tissues, including ectodermal organs, teeth, chondrocytes. Recently, MSX2 was found play important roles cancer into adjacent tissues via...
Rosmarinic acid (RA) is a phenolic originally isolated from the herb medicine Rosmarinus officinalis. The purpose of this study was to identify metabolites RA. RA incubated with human liver microsomes in presence β-nicotinamide adenine dinucleotide phosphate tetrasodium salt and/or uridine diphosphate glucuronic using glutathione (GSH) as trapping agent. After 60-min incubation, samples were analyzed high-resolution liquid chromatography tandem mass spectrometry. Under current conditions, 14...
Glioblastoma is one of the most malignant tumors and causes high mortality in cancer patients. Currently, there no highly efficient therapy against glioblastoma. Therefore, searching for a new molecular target to anti‐glioblastoma urgent necessary. In this study, we elucidated role Signal transducer activator transcription 1 ( STAT1 ) proliferation, migration apoptosis glioblastoma cells. We found that downregulation could weaken aggressiveness Besides, growth vivo was also inhibited with by...
Neonatal hypoxic-ischemic encephalopathy has high mortality, morbidity, as well the lack of effective treatment, which remain difficult problem in medical profession.Progesterone been confirmed protective effect for neonatal nerve steroid hormone, and used clinical trials Ⅱ.We review progess progesterone encephalopathy. Key words: Progesterone; Neonatal
Objective To investigate the predictive value of CT-DRAGON score for clinical outcomes after endovascular treatment in patients with acute ischemic stroke. Methods Patients stroke underwent intervention Xuzhou Central Hospital from May 2015 to June 2019 were enrolled retrospectively. was performed before treatment, and evaluated by modified Rankin Scale (mRS) at 3 months good outcome defined as mRS0-2. Multivariate logistic regression analysis used determine independent factors...