Abstract The hallmark feature of Diabetes mellitus (DM) is hyperglycemia which can lead to excess production reactive oxygen species (ROS) in the myocardium, contributing diabetic cardiomyopathy (DCM). Nuclear factor erythroid2‐related factor2 (Nrf2), a transcriptional activator, enhances its ability resist oxidative stress by activating multiple downstream anti‐oxidants, anti‐inflammatory proteins, and detoxifying enzymes. However, mechanism Nrf2 signaling HG‐induced DCM unclear. In this...

Abstract Many drugs can pass through the placenta and cause adverse effects on foetus. Thus, during Caesarean section for puerperas who have contraindications intravertebral anaesthesia, use of proper that sedative, analgesic without foetus is important. In this study, we investigated effect placental transfer dexmedetomidine under general anaesthesia. Thirty‐eight were randomly divided to receive or saline before anaesthesia induction operation. The dexmedetomidine‐treated parturients had...

Background Biochar amendments enhance crop productivity and improve agricultural quality. To date, studies on the correlation between different amounts of biochar in pakchoi ( Brassica campestris L.) quality rhizosphere soil microorganisms are limited, especially weakly alkaline soils. The experiment was set up to explore effect concentrations vegetable index bacterial community structure changes. Methods treated following ways via pot culture: blank control (CK) without added with at 1%...

Rosmarinic acid (RA) is a phenolic originally isolated from the herb medicine Rosmarinus officinalis. The purpose of this study was to identify metabolites RA. RA incubated with human liver microsomes in presence β-nicotinamide adenine dinucleotide phosphate tetrasodium salt and/or uridine diphosphate glucuronic using glutathione (GSH) as trapping agent. After 60-min incubation, samples were analyzed high-resolution liquid chromatography tandem mass spectrometry. Under current conditions, 14...

The aim of the present study was to investigate effect a high-glucose-based peritoneal dialysis solution (HGPDS) on expression pleiotrophin (PTN) and vascular endothelial growth factor (VEGF) in human mesothelial cells (HPMCs) mechanisms through which fluvastatin (Flu) protects membrane continuous ambulatory (CAPD). HPMCs were cultured with HGPDS, Flu (10-8‑10-6 mol/l) PTN (10‑30 nmol/l). VEGF examined at mRNA protein level. To define role regulation expression, HGPDS presence or absence...

This study explored the physiological and molecular mechanisms of yield increase in maize under stable soil water content (SW) conditions. Results showed that SW conditions, corn increased by 38.72 44.09% 2019 2020, respectively. Further, it was found dry matter accumulation, economic coefficient photosynthetic rate also 31.24 25.67%, 5.45 15.38% as well 29.60 31.83% 2020 However, results both activity antioxidant enzymes osmotic adjustment substances decreased When compared with moisture...

Alveolar adenoma is an isolated, well-defined peripheral lung tumor that originates from type II alveolar cells. The consists of a network simple, low-cubic, epithelium-coated lacunae with varying amounts fine and inconspicuous-to-thick spindle cells sometimes contain mucus sample matrix. Few cases have been reported. These tumors are usually detected by imaging examinations where the typically presents as peripheral, solitary cystic nodule in lung. presentation may mimic other types tumors,...

Objective To compare dexmedetomidine administered via different routes for epidural anesthesia during second cesarean section. Methods Sixty parturients who were at full term with a singleton fetus, of American Society Anesthesiologists physical statusⅠor Ⅱ, aged 22-38 yr, weighing 58-84 kg, undergoing caesarean section under anesthesia, divided into 3 groups(n=20 each)using random number table: IV infusion combined injection ropivacaine group(VDER group), mixture and group(ERD...

Objective To investigate clinical effect and safety of the 125I particle stent for treatment postoperative esophageal stricture on patients with advanced cancer.Methods Sixty after cancer operation were randomly assigned to receive a conventional self-expanding (control group) or loaded seeds (irradiation group).After implantation,the outcomes compared in terms success rate implantation,relief dysphagia,survival time,and complications related procedure.Dysphagia was grade 0-4.The t test x2...

This study was aimed to investigate the regulatory effect of protein disulfide isomerase (PDI) on platelet GPIbα ectodomain shedding.The washed platelets were obtained from healthy volunteers. Platelets incubated with PDI inhibitor bacitracin before stimulation PMA (Phorbol-12-myristate-13-acetate), dibucaine and collagen. The N-terminal domain in supernatant detected by Western blot, expression intraplatelet ROS levels measured flow cytometry.neither GC content nor changed after donors only...

Objective To investigate the placental transfer and neonatal effects of dexmedetomidine during cesarean section under general anesthesia. Methods Thirty-eight nulliparous parturients, American Society Anesthesiologists physical statusⅠ or Ⅱ, aged 22-37 yr, weighing 56-82 kg, who were at full term with a singleton fetus, scheduled for elective caesarean anesthesia, randomly divided into 2 groups (n=19 each) using random number table: group (group D) normal saline N). In D, was infused...

Objective To study the variation of serum interleukin-6 (IL-6),interleukin-10 (IL-10),tumor necrosis factor alpha(TNF-α) and heat shock protein 70(HSP70) in patients underwent gynecological laparoscopic operations using abdominal walllifting(a gasless technique) or pneumoperitoneum methods under different anesthesia.Methods Fifty-seven scheduled for laparoscopy,with operation time less than 100 min,were randomly divided into three groups ( Ⅰ,Ⅱ,Ⅲ ) with 19cases each group respectively.Group Ⅰ...

Objective To determine the optimum dose of normal saline (NS) for preloading epidural space required to prevent injury blood vessel by catheter placement caesarean section.Methods Two hundred ASA Ⅰ or Ⅱ parturients with a single baby at full term in vertex presentation,aged 24-35 yr,weighing 63-78 kg,scheduled section under continuous anesthesia,were randomly divided into4 groups (n-50 each):control group (group Ⅰ),NS2 ml Ⅱ),NS5 Ⅲ)and NS 10 Ⅳ).The puncture was performed L2-3 interspace Tuohy...

Objective To explore the best fat liquefaction prevention measures for gynecological obese patients with abdominal incision.Methods 84 incision were divided into observation group(46 cases)and control group(38 cases),according to negative pressure attract ball placed or not in subcutaneous layer during operation.Patients both groups taken physiotherapy.Results The rate of group was 8.7％,which lower than that group(26.3％)(x2=4.65,P＜0.05).Conclusion It is very important keep dry,smooth...

Objective To evaluate the accuracy of variation epidural labor analgesia in predicting cesarean section. Methods A total 1 200 parturients with a single baby who were at full term singleton fetus, aged 22-34 yr, weighing 60-85 kg, American Society Anesthesiologists physical status Ⅰ or Ⅱ, volunteered for pain relief, enrolled study.Epidural (patient-controlled analgesia)was performed when uterine contraction was regular and cervical dilatation 2-3 cm.Patient-controlled solution...

Orthopedic infections affect the joins or bones and sometimes affects both simultaneously. More often, orthopedic occur during after surgery, particularly with joint replacement surgeries of hip bone knee bone. Most are arised by bacteria Streptococcus , Staphylococcus Pseudomonas . On other hand, nanomaterials have been used for implanting able to attach on implanted materials damaged tissue cause infection. Monitoring infection in patients surgery is mandatory successful treatment avoid...