Zheng Xian Thng

ORCID: 0000-0003-3275-7537
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About
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Research Areas
  • Ocular Diseases and Behçet’s Syndrome
  • Retinal and Optic Conditions
  • Cytomegalovirus and herpesvirus research
  • Systemic Lupus Erythematosus Research
  • Syphilis Diagnosis and Treatment
  • Vasculitis and related conditions
  • Retinal Diseases and Treatments
  • Retinal Imaging and Analysis
  • Toxoplasma gondii Research Studies
  • Ophthalmology and Visual Health Research
  • Herpesvirus Infections and Treatments
  • Artificial Intelligence in Healthcare and Education
  • Hemodynamic Monitoring and Therapy
  • Retinal Development and Disorders
  • Optical Imaging and Spectroscopy Techniques
  • COVID-19 Clinical Research Studies
  • Medical Imaging and Analysis
  • Ocular Surface and Contact Lens
  • Clinical Reasoning and Diagnostic Skills
  • Mosquito-borne diseases and control
  • Sarcoidosis and Beryllium Toxicity Research
  • IgG4-Related and Inflammatory Diseases
  • Surgical Simulation and Training
  • Cerebral Venous Sinus Thrombosis
  • Infectious Diseases and Tuberculosis

Stanford University
2023-2025

Tan Tock Seng Hospital
2016-2025

Singapore National Eye Center
2025

Smith-Kettlewell Eye Research Institute
2023-2024

Nanyang Technological University
2022

Post Graduate Institute of Medical Education and Research
2021

MOH Holdings
2019

Accurate diagnosis and timely management are vital for favorable uveitis outcomes. Artificial Intelligence (AI) holds promise in medical decision-making, particularly ophthalmology. Yet, the diagnostic precision advice from AI-based chatbots lack assessment.

10.1080/09273948.2023.2253471 article EN Ocular Immunology and Inflammation 2023-09-18

Abstract Purpose To report IgG4-related ophthalmic disease (IgG4-ROD) presenting as posterior scleritis in a pediatric patient. Observations A 7-year-old girl presented with proptosis, painful eyelid swelling, and restricted extraocular movements (EOM) of her left eye (OS). Visual acuity (VA) was 20/20 right (OD) counting fingers (CF) at 1 foot OS. Slit lamp examination revealed 2 + anterior chamber (AC) cells, optic disc edema (ODE) elevated appearance macula Optical coherence tomography...

10.1186/s12348-025-00459-9 article EN cc-by Journal of Ophthalmic Inflammation and Infection 2025-03-27

This is the studyto investigate correlation between macular cone density (MCD) and flicker electroretinogram (ERG) response in healthy eyes. In this exploratory study, 23 eyes from 12 subjects were enrolled study. The fixed-luminance full-field (ffERG) responses of retina MCDs at 24 locations measured using Diopsys® NOVA™ system rtx1 adaptive optics retinal camera, respectively. Regression analysis was employed to evaluate correlations. mean age 30 ± 3 years. average magnitudes phase 13.44...

10.3390/life15050694 article EN cc-by Life 2025-04-24

To evaluate risk factors associated with development of anti-adalimumab antibodies (AAA) in patients non-infectious uveitis treated adalimumab.

10.1016/j.heliyon.2024.e29313 article EN cc-by-nc-nd Heliyon 2024-04-05

PurposeTo compare the utility of ChatGPT-4 as an online uveitis patient education resource with existing websites.DesignEvaluation technology.ParticipantsNot applicable.MethodsThe term "uveitis" was entered into Google search engine, and first eight non-sponsored websites were selected to be enrolled in study. Information regarding for patients extracted from Healthline, Mayo Clinic, WebMD, National Eye Institute, Ocular Uveitis Immunology Foundation, American Academy Ophthalmology,...

10.1016/j.xops.2024.100594 article EN cc-by-nc-nd Ophthalmology Science 2024-08-08
Zheng Xian Thng Ikhwanuliman Putera Ilaria Testi K. Chan Mark Westcott and 95 more Soon-Phaik Chee Andrew D. Dick John H. Kempen Bahram Bodaghi Jennifer E. Thorne Talin Barisani‐Asenbauer Marc D. de Smet Justine R. Smith Peter McCluskey Rina La Distia Nora Douglas A. Jabs Joke de Boer H. Nida Sen Debra A. Goldstein Moncef Khairallah Janet L. Davis James T. Rosenbaum Nicholas P. Jones Quan Dong Nguyen Carlos Pavésio Rupesh Agrawal Vishali Gupta Zheng Xian Thng Ikhwanuliman Putera Rupesh Agrawal Ilaria Testi Mark Westcott Soon-Phaik Chee Andrew D. Dick John H. Kempen Manfred Zierhut Bahram Bodaghi Jennifer E. Thorne Talin Barisani‐Asenbauer Marc D. de Smet Justine R. Smith Peter McCluskey Rina La Distia Nora Douglas A. Jabs Joke de Boer H. Nida Sen Debra A. Goldstein Moncef Khairallah Janet L. Davis Quan Dong Nguyen Carlos Pavésio Vishali Gupta Alan G. Palestine Alastair K. Denniston Alessandro Invernizzi Radgonde Amer Amitabh Kumar Andrè Luiz Land Curi Aniruddha Agarwal Anita Chan Sook Yee Annabelle A. Okada Ariel Schlaen Arnd Heiligenhaus Avinash Gurbaxani SBala Murugan Cecilia S. Lee Dipankar Das Edoardo Baglivo Ester Carreño J. Fernando Arévalo Francesco Pichi Harvey S. Uy Hassan Al-Dhibi James T. Rosenbaum Justus G. Garweg Jyotirmay Biswas Kalpana Babu Murthy Laure Caspers Luca Cimino Lyndell L. Lim Maite Sáinz de la Maza Mamta Agarwal Manabu Mochizucki Manisha Agarwal Marion R. Munk Massimo Accorinti Mudit Tyagi Nicholas P. Jones Nisha Acharya Padmamalini Mahendradas Parthopratim Dutta Majumder Philip I. Murray Phoebe Lim Piergiorgio Neri Reema Bansal Russell W. Read Salil Mehta Samir S. Shoughy Shawki Shahana Mazumdar Shishir Narain

10.1038/s41433-023-02631-8 article EN Eye 2023-07-07

To investigate the incidence and risk factors for neovascular glaucoma (NVG) after vitrectomy in patients with proliferative diabetic retinopathy (PDR). Patients were categorized into two subgroups based on their treatment regimen: one group received only (Group 1), while other combined phacovitrectomy 2). A comparative analysis was conducted to evaluate distinguishing characteristics of groups. Kaplan-Meier survival used determine NVG following surgery. Furthermore, multivariate using Cox...

10.1038/s41598-024-73395-8 article EN cc-by-nc-nd Scientific Reports 2024-09-28

We examined the association between bioimpedance profiles and optical coherence tomography (OCT) features in patients with diabetic macular edema (DME). This cross-sectional study included 100 eyes of type 2 diabetes mellitus. The systemic fluid status was assessed using extracellular water-to-total body water ratio (ECW/TBW) phase angle (PhA), which measured equipment. ECW/TBW higher DR (diabetic retinopathy) DME group than no without groups (p = 0.007 p 0.047, respectively); however,...

10.3390/jcm12206676 article EN Journal of Clinical Medicine 2023-10-22

Background: To describe longitudinal changes in patients with non-paraneoplastic autoimmune retinopathy (npAIR) by utilizing different diagnostic modalities/tests. Methods: The index study is a retrospective review of sixteen eyes eight from tertiary care eye hospital diagnosed npAIR. Multiple modalities such as wide-angle fundus photography (WAFP), WA autofluorescence (WAFAF), spectral-domain optical coherence tomography (SD-OCT), Goldmann visual field (GVF) perimetry, microperimetry (MP),...

10.3390/diagnostics13213376 article EN cc-by Diagnostics 2023-11-03

To report a case of bisphosphonate-induced bilateral anterior uveitis and choroidal effusions with secondary angle closure in 64-year-old female patient.Observational report.A woman history scleroderma antiphospholipid syndrome, presented painless blurring vision after commencement alendronate. Clinical examination revealed resultant the left eye. Ultrasound biomicroscopy showed anteriorly rotated ciliary bodies. There was also -2D myopic shift On drug cessation, complete resolution seen...

10.1097/icb.0000000000000850 article EN Retinal Cases & Brief Reports 2019-01-19

Introduction Uveitis is a heterogeneous group of ocular conditions characterized by inflammation the uveal tract and one leading causes vision impairment. In developed countries, noninfectious uveitis (NIU) represents most cases challenging to treat due its severity, chronicity, high recurrence rates. The advent anti-tumor necrosis factor-α (anti-TNF-α) agents have dramatically improved outcomes changed treatment paradigms in NIU.

10.1080/13543784.2024.2311186 article EN Expert Opinion on Investigational Drugs 2024-02-01

Repository corticotropin injection (RCI) has been suggested to exert immunomodulatory and anti-inflammatory effects in ocular inflammation. The index retrospective study aimed evaluate the efficacy tolerability of subcutaneous RCI patients with active scleritis or uveitis.

10.1186/s12348-024-00428-8 article EN cc-by Journal of Ophthalmic Inflammation and Infection 2024-10-24

Purpose: To report a case of cystoid macular edema (CME) secondary to immune recovery uveitis (IRU) in patient with previous history cytomegalovirus (CMV) retinitis and leukemia, which was successfully treated tocilizumab (TCZ), an interleukin-6 (IL-6) receptor antagonist. Method: The clinical records the were reviewed, focusing on demographics, image findings, course. Results: A 17-year-old female past medical T-cell acute lymphoblastic leukemia (T-ALL) undergoing chemotherapy for two years...

10.59249/nqrt7239 article EN cc-by-nc The Yale Journal of Biology and Medicine 2024-12-19
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