A5014412339- Ocular Diseases and Behçet’s Syndrome
- Retinal and Optic Conditions
- Infectious Diseases and Tuberculosis
- Ocular Infections and Treatments
- Sarcoidosis and Beryllium Toxicity Research
- Drug-Induced Ocular Toxicity
- Retinal Diseases and Treatments
- Vasculitis and related conditions
- Systemic Lupus Erythematosus Research
- Mosquito-borne diseases and control
- Antifungal resistance and susceptibility
- Infectious Encephalopathies and Encephalitis
- Cytomegalovirus and herpesvirus research
- Diagnosis and treatment of tuberculosis
- Sinusitis and nasal conditions
- Radiology practices and education
- Viral Infections and Vectors
- Mycobacterium research and diagnosis
- Ophthalmology and Visual Health Research
- Viral Infections and Outbreaks Research
- Social Media in Health Education
- Clinical Nutrition and Gastroenterology
- Otitis Media and Relapsing Polychondritis
- Vascular Anomalies and Treatments
- Ocular Disorders and Treatments
Lilavati Hospital & Research Centre
2013-2024
Collaborative Group (United States)
2024
Massachusetts General Hospital
2016-2022
University of Pennsylvania
2020
Penn Center for AIDS Research
2020
University of Pennsylvania Health System
2020
Kokilaben Dhirubhai Ambani Hospital
2015
Madras Diabetes Research Foundation
1997
Coronavirus disease 2019 (COVID-19) infections may be associated with a wide range of bacterial and fungal co-infections. We report the case patient COVID-19 infection, which, during course treatment, developed rhino-orbital mucormycosis. A 60- year-old male patient, longstanding diabetic, positive reverse-transcriptase polymerase chain reaction (RT-PCR) for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was admitted treatment. He received parenteral meropenem oral oseltamivir...
Purpose: To standardize a nomenclature system for defining clinical phenotypes, and outcome measures reporting research data in patients with ocular tuberculosis (OTB).Methods: Uveitis experts initially administered further deliberated the survey an open meeting to determine propose preferred terms related OTB, describing phenotypes treatment outcomes.Results: The group of reached consensus on terming uveitis attributable (TB) as tubercular uveitis. working introduced SUN-compatible that...
Patients on linezolid-containing drug-resistant TB (DR-TB) regimen often develop adverse-events, particularly peripheral and optic neuropathy. Programmatic data experiences of linezolid-associated neuropathy from high DR-TB burden settings are lacking. The study aimed to determine the frequency risk-factors associated with document related treatment/care patients regimens.This was a retrospective cohort using routine clinical laboratory in Médecins Sans Frontières (MSF) HIV/DR-TB clinic...
The prevalence and the patterns of ocular inflammatory disease tuberculosis (TB) are largely undocumented among Multidrug Resistant TB (MDR-TB) patients co-infected with Human Immunodeficiency Virus (HIV) on antituberculosis antiretroviral therapy (ART).Lilavati Hospital Research Center Médecins Sans Frontières (MSF) organized a cross-sectional ophthalmological evaluation HIV/MDR-TB followed in an MSF-run HIV-clinic Mumbai, India, which included measuring visual acuity, slit lamp dilated...
Purpose: To determine the prevalence of ocular involvement in patients with acute disseminated tuberculosis and to assess findings associated involvement. Methods: Assessment all intensive care (ICU) admissions a differential diagnosis mycobacterial sepsis during period one year, detailed systemic ophthalmic evaluation. Results: Of 342 admissions, 24 were suspected have infection. these cases, 10 proven sepsis, six which (60%) showed evidence Five (83%) had choroidal tubercles (16%) retinal...
An international, expert led consensus initiative was set up by the Collaborative Ocular Tuberculosis Study (COTS) group to develop systematic, evidence, and experience-based recommendations for treatment of ocular TB using a modified Delphi technique process. In first round Delphi, identified clinical scenarios pertinent based on five phenotypes (anterior uveitis, intermediate choroiditis, retinal vasculitis, panuveitis). Using an interactive online questionnaires, guided background...
To determine the prevalence and clinical features of ocular tuberculosis in patients with acquired immune deficiency syndrome (AIDS).Prospective cross-sectional study.Detailed history examination 46 (92 eyes) outpatient department an AIDS clinic.Seventeen (36.9%) had radiological evidence pulmonary tuberculosis. Of these, four (23.5%) showed findings consistent Lesions included tubercles (1 eye 3 patients) chorioretinitis 1 patient). Commonly, these abdominal Hemorrhages, cotton-wool spots,...
Hantavirus infections are an emerging infectious disease that is beginning to be recognized both worldwide and in India as a cause of hemorrhagic fever may present pulmonary syndrome or renal syndrome.Reports ocular involvement rare include transient myopia, low intraocular pressure, conjunctival hemorrhages changes dimensions.
Neurotuberculosis is a relatively common form of tuberculosis and may be seen in 1-10% patients systemic present several forms. Ocular lesions are frequently seen, most commonly optic nerve lesions. Limited data available for choroidal tubercles. We conducted prospective study 1) to determine the prevalence tubercles cohort neurotuberculosis as well its relative various morphological manifestations 2) role co-existent tuberculous infection.IRB-approved cross-sectional observational study. A...
To report the clinical, investigational and PET/CT scan findings of patients with presumed ocular tuberculosis suggest a hypotheses for pathogenesis.Retrospective case review. Included were 10 males 17 females an age range: 23-71 years.Clinical include granulomatous or non-granulomatous anterior uveitis, intermediate panuveitis, vasculitis, multifocal serpiginous-like choroidopathy. A total 13 scans normal 14 showed systemic disease. The commonest finding was metabolically active...
Materials and methods: The clinical investigational findings of 11 patients were reviewed retrospectively. These included 6 males 5 females with a mean age 46.2 years. 21 eyes in the data analysis. Clinical presentations include 15 anterior uveitis, 2 retinal vasculitis, panuveitis multifocal choroidopathy.
Introduction Accelerated hypertension, that is a systolic blood pressure greater than 180 mmHg and diastolic 120 often accompanied by fundoscopic signs with the potential of systemic visual morbidity. We report on clinical optical coherence tomography angiography (OCTA) findings in cohort hypertensive patients accelerated hypertension. Methods Patients, presenting to emergency room/intensive care unit, who met definition hypertension (a >180/120 mmHg,), were triaged intensive unit. Following...
A 28-year-old female patient with disseminated tuberculosis and choroidal tubercles on a regimen of systemic antitubercular therapy underwent fundus photography optical coherence tomography (OCT). This was carried out monthly until complete healing the tubercle seen. The consisted central white-yellow core, consistent choroiditis, faint hyperpigmentation surrounding it. There diffuse rim inflammation. By second month, hyperpigmented more prominent as were outer edges both core rim. Over...
The aim of this communication was to report the fundus fluorescein angiography findings in three patients with choroidal tubercles. In all cases, there a marked peritubercular inflammation. tubercles themselves showed an initial hypofluorescence or minimal hyperfluorescence that increased late phases. Clinicians need be familiar these new as they may help diagnosis ocular tuberculosis.
Aspergillus species are fungi that commonly found in soil and decaying vegetation have the potential to cause an orbital apex syndrome is marked by ophthalmoplegia or vision loss. We report clinical investigational findings outcomes of two patients with syndrome. The first patient was a 26-year-old female, premorbidly healthy, who presented gradually increasing proptosis left eye reduction vision. An MRI revealed consistent proptosis, pansinusitis soft tissue opacity involving optic nerve...
Chronic renal failure is a common sequel of inflammatory disease or diabetes mellitus. As result the immunosuppression that induced by uremia, hemodialysis posttransplant immunosuppressive medication, these patients are at higher risk opportunistic infections. Various viral, bacterial and mycobacterial infections have been reported. Tuberculosis systemic infection but reports ocular involvement with pulmonary disseminated tuberculosis rare. We report findings in two postrenal-transplant whom...
We report the clinical and perimetric findings of three patients with ethambutol toxicity an extended use regimen. In this observational case series, we extracted data from records that included age, sex, complaints, details current disease, anti-tubercular therapy, ocular findings, findings. identified patients, two female one male ages ranging 16 to 65 years (mean: 37 years). The patterns observed were incomplete homonymous hemianopia in bitemporal one. Incomplete was predominant finding,...
A 61-year-old male presented with visual loss in the left eye. CT scan of chest revealed multiple lung cavities both lungs. He had a positive C-ANCA suggestive granulomatosis polyangiitis. There were areas superficial retinal opacification right eye and anterior ischemic optic neuropathy An optical coherence tomography (OCT)/optical angiography (OCTA) capillary dropout flow void choriocapillaris. The patient underwent immunosuppressive therapy at follow-up, there was reduction voids. Use...