Heloísa Nascimento
- Ocular Diseases and Behçet’s Syndrome
- Retinal and Optic Conditions
- Ocular Infections and Treatments
- Toxoplasma gondii Research Studies
- Herpesvirus Infections and Treatments
- Ocular Surface and Contact Lens
- Syphilis Diagnosis and Treatment
- Cytomegalovirus and herpesvirus research
- Retinal Diseases and Treatments
- Intraocular Surgery and Lenses
- Retinal Imaging and Analysis
- Extracellular vesicles in disease
- Sarcoidosis and Beryllium Toxicity Research
- Systemic Lupus Erythematosus Research
- Corneal Surgery and Treatments
- Corneal surgery and disorders
- Vasculitis and related conditions
- Glaucoma and retinal disorders
- Food composition and properties
- Mosquito-borne diseases and control
- Traumatic Ocular and Foreign Body Injuries
- Probiotics and Fermented Foods
- Rabies epidemiology and control
- Microbial Metabolites in Food Biotechnology
- Long-Term Effects of COVID-19
Universidade Federal da Paraíba
2021-2024
Universidade Federal de São Paulo
2015-2024
Instituto da Visão
2015-2024
Instituto Paulista de Ensino e Pesquisa
2020-2024
Collaborative Group (United States)
2024
Universidade de São Paulo
2024
Instituto Paulista de Estudos e Pesquisas em Oftalmologia
2021-2023
Hospital do Servidor Público Municipal
2023
Institut de la Vision
2022
Brazilian Academy of Sciences
2021
An international, expert-led consensus initiative to develop systematic, evidence-based recommendations for the treatment of noninfectious uveitis in era biologics.The availability biologic agents human eye disease has altered practice patterns management uveitis. Current guidelines are insufficient assure optimal use noncorticosteroid systemic immunomodulatory agents.An international expert steering committee comprising 9 specialists (including both ophthalmologists and rheumatologists)...
Purpose To describe a case of acute thyroiditis and bilateral optic neuritis associated with SARS-CoV-2 vaccination.
Abstract The challenge of COVID-19 has rapidly changed medical management worldwide. relatively small time from pandemic to vaccines regulatory approval triggered a race toward development. However, important questions regarding SARS-CoV-2 remain. A case complete Vogt-Koyanagi-Harada (VKH) Syndrome that occurred 4 days following vaccination and another patient developed VKH 14 post clinical onset are presented. causal relationship between uveitis may exist.
Purpose: To standardize a nomenclature system for defining clinical phenotypes, and outcome measures reporting research data in patients with ocular tuberculosis (OTB).Methods: Uveitis experts initially administered further deliberated the survey an open meeting to determine propose preferred terms related OTB, describing phenotypes treatment outcomes.Results: The group of reached consensus on terming uveitis attributable (TB) as tubercular uveitis. working introduced SUN-compatible that...
Recent reports from different world regions suggest ocular syphilis is re-emerging, in parallel with an increasing incidence of the systemic infection globally. We conducted a large observational study 127 persons consecutively treated for at public medical centers Brazil over 2.5-year period ending July 2015. Of 104 individuals serologically tested human immunodeficiency virus (HIV), 34.6% were positive. Ophthalmological evaluations included measurement Snellen visual acuity and intraocular...
The presence of the SARS-CoV-2 virus in retina deceased patients with COVID-19 has been suggested through real-time reverse polymerase chain reaction and immunological methods to detect its main proteins. eye shown abnormalities associated infection, retinal changes were presumed be secondary microvascular changes.To demonstrate viral particles relevant proteins eyes COVID-19.The from enucleated confirmed infection submitted immunofluorescence transmission electron microscopy processing at a...
To describe the clinical profile of uveitis and analyze changes over a 34-year period in frequency different entities demographics, anatomic data, diagnoses, systemic associations São Paulo, Brazil.A total 1053 consecutive patients who presented for first time at outpatient clinic were analyzed prospective, observational study, conducted between July 2012 September 2013. Age, gender, characteristics, visual acuity, etiologic diagnoses with without human immunodeficiency virus (HIV)...
To describe optical coherence tomography angiography (OCT-A) findings in patients with retinal vasculitis and to compare them current fluorescein (FA) findings.This was an observational case series. Nineteen eyes 10 of various etiologies were imaged FA (TRC-50DX, Topcon) OCT-A (SD-OCT, Optovue). The images reviewed analyzed.The mean age 36 years (range 24-67 years); there three males seven females. primary vessels involved veins (89%). Fourteen (74%) had active inflammatory disease during...
The primary purpose of this study was to assess vascular retinal findings temporally related COVID-19 vaccination. With greater information regarding all possible future adverse events, we hope understand the real dimension and relevance what presented.Eleven patients with visual complaints after vaccination were enrolled. Data on following included: age, sex, vaccine, time symptom onset, systemic findings, medical history, best-corrected acuity, ocular by slit-lamp biomicroscopy as well...
To objectively evaluate YAG laser vitreolysis for symptomatic vitreous floaters using color photo imaging.In this interventional and prospective study, 32 eyes of patients with secondary to posterior detachment (PVD) were treated a single session yttrium aluminum garnet (YAG) laser. Primary outcomes objective subjective changes measured by masked grading fundus photographs National Eye Institute Visual Functioning Questionnaire 25 (NEI VFQ-25), respectively. Secondary included Early...
Purpose: Uveal melanoma (UM) is the most common intraocular malignant tumor in adults. Extracellular vesicles (EVs) have been extensively studied as a biomarker to monitor disease patients. The study of new biomarkers patients could prevent metastasis by earlier diagnosis. In this study, we determined proteomic profile EVs isolated from aqueous humor (AH), vitreous (VH), and plasma UM comparison with cancer-free control Methods: AH, VH were collected seven after enucleation; AH cataract...
To evaluate the efficacy of a prophylactic regimen daily topical 0.5% moxifloxacin and 5% povidone-iodine (PI) in patients with Boston type I keratoprosthesis (KPro) to assess applicability novel molecular diagnostic technique analyze ocular surface microbiota these patients.Ten had their inferior conjunctival fornix sampled for standard culture methods before addition PI were considered control group (group 1). The KPro-donor cornea interface 10 treated mentioned analyzed by using...
To evaluate the concentration of tear lysozyme in individuals with Sjogren´s syndrome, meibomian gland dysfunction, and non-dry-eye disease.Ninety subjects were recruited for this study, including 30 disease. All referred to participate study based on a "dry eye" investigation. They underwent complete ocular surface ophthalmic examination encompassing disease index, biomicroscopy, break-up time, Schirmer test type I, conjunctival vital staining fluorescein lissamine green, concentration,...
Purpose: Nontuberculous mycobacteria keratitis is a rare but challenging complication of laser in situ keratomileusis (LASIK). This study was conducted to determine the source(s) infection cluster cases after LASIK and describe this outbreak patients' outcomes. Methods: In retrospective, case series, single-center study, 86 patients were included who underwent or photorefractive keratectomy between December 2011 February 2012. Corneal scrapes from affected eyes, samples tap distilled water,...
Purpose: To evaluate the effectiveness of treatments for ocular toxoplasmosis (OT).Methods: A review charts was conducted from patients who experienced an active episode OT treated at Federal University São Paulo and associated sites. were reviewed to determine treatment based on clinical judgment, taking course outcome into consideration in addition change best-corrected visual acuity. Treatment emergent adverse events (TEAEs) used assess safety.Results: Overall, 451/1200 patient met...