A5034821414- Ocular Diseases and Behçet’s Syndrome
- Retinal and Optic Conditions
- Ocular Oncology and Treatments
- Ocular Infections and Treatments
- Connexins and lens biology
- Sarcoidosis and Beryllium Toxicity Research
- Ocular Disorders and Treatments
- Medical Malpractice and Liability Issues
- Cancer-related molecular mechanisms research
- Retinal Diseases and Treatments
- Glaucoma and retinal disorders
- Retinal and Macular Surgery
- Syphilis Diagnosis and Treatment
- Intraocular Surgery and Lenses
- Retinal Development and Disorders
- RNA regulation and disease
- Reproductive tract infections research
- Traumatic Ocular and Foreign Body Injuries
- Historical and Scientific Studies
- Autoimmune and Inflammatory Disorders Research
- Botulinum Toxin and Related Neurological Disorders
- RNA Interference and Gene Delivery
- Drug-Induced Ocular Toxicity
- Cell death mechanisms and regulation
- Corneal Surgery and Treatments
Emory University
2019-2020
Emory Eye Center
2017-2020
Kaiser Permanente
2020
Johns Hopkins Medicine
2011-2018
Johns Hopkins University
2011-2018
Johns Hopkins Hospital
2014-2018
Oregon Health & Science University
2017-2018
Legacy Health
2017
University of California, San Francisco
2010-2016
An international, expert-led consensus initiative to develop systematic, evidence-based recommendations for the treatment of noninfectious uveitis in era biologics.The availability biologic agents human eye disease has altered practice patterns management uveitis. Current guidelines are insufficient assure optimal use noncorticosteroid systemic immunomodulatory agents.An international expert steering committee comprising 9 specialists (including both ophthalmologists and rheumatologists)...
Although a variety of well-characterized diseases, such as sarcoidosis and granulomatosis with polyangiitis, affect the lacrimal gland, many patients dacryoadenitis are diagnosed having nonspecific orbital inflammation (NSOI) on basis histology systemic disease evaluation. The ability to further classify in these should facilitate selection effective therapies.To test priori hypothesis that gene expression profiles would complement clinical histopathologic evaluations identifying diseases...
Idiopathic disease is the most frequent diagnosis in a uveitis clinic. The need to distinguish sarcoidosis from idiopathic controversial. However, cardiac involvement can be life-threatening.To report series of patients with and illustrate importance categorizing causes uveitis.This retrospective observational case reviewed medical records 249 who were referred Casey Eye Institute between July 1, 2008, February 28, 2017.We describe initially received but subsequently sarcoidosis. Clinical...
Purpose: To describe the effectiveness of periocular corticosteroid injections for control intraocular inflammation associated with noninfectious uveitis.Methods: A total 81 patients (109 eyes) who received a injection were evaluated active inflammation, visual acuity, pressure, degree and presence ocular complications, including macular edema.Results: Of all eyes, 36% (95%CI: 25%, 45%) demonstrated clinical resolution at 1-month visit after first injection, 48% 37%, 59%) 3 months. For...
Cosmetic injection of hyaluronic acid (HA) and other fillers is increasingly common, the late complications these relatively new procedures are now coming to medical attention. Three patients with delayed periocular swelling that began years after HA described, CT, MRI, histopathologic characterization. While marketed as having a temporary effect several months, authors demonstrate they may persist in body for up 9 years. Unlike most previous reports, there was no inflammatory reaction or...
Survivin (SVV) is a multifunctional protein that has been implicated in the development of neointimal hyperplasia. Nuclear SVV essential for mitosis, whereas mitochondria cytoprotective function. Here, we investigated effects RNA interference (RNAi)-mediated knockdown on cell cycle kinetics, apoptosis, migration, and gene expression primary cultured vascular smooth muscle cells (VSMCs) from human saphenous vein. Primary Human VSMCs were obtained veins under standard conditions. was achieved...
To report novel optical coherence tomography findings in a case of anti-α-enolase cancer associated retinopathy. An elderly female presented with bilateral decreased vision and recent diagnosis ovarian carcinoma. Optical demonstrated loss outer retinal structures macular edema. Serum testing found antibodies against α-enolase 82–84 kDa proteins. Outer showed recovery, edema resolved repeat anti-retinal antibody became negative following therapy topical difluprednate treatment. Cancer...
A 64-year-old man with a past medical history of liver transplantation on chronic immunosuppressive therapy presented gradual worsening vision over 2 months in his right eye. His recent Aspergillus and Nocardia pneumonia positive bronchoalveolar lavage, concert vitritis subretinal abscess, were concerning for endogenous endophthalmitis. sputum culture transbronchial lung biopsy stains grew farcinica although aqueous humor sampling was negative. He treated four serial amikacin intravitreal...
To report and analyze the causes outcomes of malpractice litigation in ophthalmic trauma.The Westlaw® database was reviewed for ophthalmology United States between 1930 2014. All trauma cases were included compared to non-traumatic cases.Forty-four included. Of these cases, 90.9% plaintiffs male 54.8% as a whole (P=<0.001); 34.1% involved minor 6.4% (P=<0.001). Cases involving minors more likely be resolved favor plaintiff than adult (53.3% vs 37.9%); however, this not found statistically...