A5057521434- Cervical Cancer and HPV Research
- Global Cancer Incidence and Screening
- Reproductive tract infections research
- Genital Health and Disease
- Endometrial and Cervical Cancer Treatments
- Carcinogens and Genotoxicity Assessment
- S100 Proteins and Annexins
- Cell Adhesion Molecules Research
- Nutritional Studies and Diet
- Ovarian cancer diagnosis and treatment
- Protease and Inhibitor Mechanisms
- Cancer-related gene regulation
- Water Treatment and Disinfection
- Medicine and Dermatology Studies History
- Toxic Organic Pollutants Impact
- Molecular Biology Techniques and Applications
- Spanish Literature and Culture Studies
- Enterobacteriaceae and Cronobacter Research
- Medieval and Early Modern Iberia
- Sulfur Compounds in Biology
- Genetic factors in colorectal cancer
- COVID-19 and healthcare impacts
- Coenzyme Q10 studies and effects
- Genetically Modified Organisms Research
- Phagocytosis and Immune Regulation
Institut Català d'Oncologia
2015-2025
Institut d'Investigació Biomédica de Bellvitge
2015-2025
Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública
2021-2025
Universidad de Alcalá
2025
Stanford University
2024
Duran i Reynals Hospital
2023
Training Programs in Epidemiology and Public Health Interventions Network
2020
Centro de Investigación Biomédica en Red de Cáncer
2018
Instituto de Salud Carlos III
2018
Hospital Universitari Sant Joan de Reus
2018
New molecular approaches are being developed to detect endometrial cancer using minimally invasive sampling methods. This study aims evaluate the acceptability of self-collected cervicovaginal samples among women with Lynch syndrome, a group at high risk for developing cancer. Participants collected self-samples and answered an at-home questionnaire in cross-sectional study. Self-samples from subset these were analyzed somatic mutations next-generation sequencing (NGS), targeting panel 47...
To evaluate, using an online non-probability sample, the beliefs about and attitudes towards cancer prevention of people professing vaccination scepticism or conspiracy theories.Cross sectional survey.Data collected mainly from ForoCoches (a well known Spanish forum) other platforms, including Reddit (English), 4Chan HispaChan (Spanish), a language website for (mejorsincancer.org) January to March 2022.Among 1494 responders, 209 were unvaccinated against covid-19, 112 preferred alternative...
A randomized clinical trial was conducted to compare the impact of two different instructions on vaginal self-sampling in its acceptability and willingness for future screening rounds among women attending cervical cancer (CCS). From November 2018 May 2021, aged 30-65 living Spain CCS were 1:1 arms. In "On-site training arm (TRA)", took a self-sample at primary health care centre following provider's instructions. "No on-site (NO-TRA)" only received take home. All had return new sample...
Abstract Objective To conduct a comprehensive assessment of dietary intakes nitrites and N -nitrosodimethylamine (NDMA). Subjects setting A study was conducted within the Spanish cohort European Prospective Investigation in Cancer Nutrition (EPIC) to assess intake food sources these compounds adults. The included 41 446 health volunteers, aged 29–69 years, from Northern Southern regions. Usual estimated by in-person interviews using computerised questionnaire. Results geometric mean 0.994 mg...
The objective of this study was to describe prior negative screening history and symptoms around the time diagnosis incident cervical cancer (CC) cases diagnosed between 2000 2010 within Asturias public health system.Records from 374 women with CC all hospitals in were retrieved. Clinical information, FIGO stage previous cytological data extracted clinical histopathological records. Proportional differences assessed using chi-square tests. Logistic regression analysis used estimate odds...
Aromatic compounds such as polycyclic aromatic hydrocarbons, arylamines and heterocyclic amines require metabolic activation to form metabolites able bind DNA, a process mediated by polymorphic enzymes. We measured DNA adducts in white blood cells the 32 P-post-labelling assay sample of 296 healthy adults (147 men 149 women) from five regions Spain. also analyzed functional polymorphisms genes CYP1A1 , CYP1A2 EPHX1 GSTM1 GSTT1 NAT2 SULT1A1 . A significant increased level was found related...
Background: The Public Health system in Catalonia, Spain provides a free of charge opportunistic cervical cancer screening. In June 2006 revised recommendations for screening was introduced to increase coverage and promote three-year interval between tests. Aim: This study examines prevalence cytology abnormalities Catalonia by immigration status. Methods: analyses the cytologies registered among women aged 25-65 that have been attended at Primary Centers (PHC) any reason (n=1,242,105)...
Objective . Audit of women with invasive cervical cancer (CC) is critical for quality control within screening activities. We analysed the history in 10 years preceding study entry and without CC during 2000–2011. Methods 323 from six pathology departments Catalonia (Spain) 23,782 negative cytology were compared. Age, previous cytologies, histological type FIGO stage collected registries. Logistic regression analysis was used to estimate odds ratios (OR) 95% confidence intervals (CI95%)....
Poor attendance to cervical cancer (CC) screening is a major risk factor for CC. Efforts capture underscreened women are considerable and once agree participate, the provision of longitudinal validity test paramount relevance. We evaluate addition high HPV (HPV) cytology as primary among in prediction intraepithelial lesions grade 2 or worse (CIN2+). Women were included study if they older than 39 years with no evidence previous five within Public Primary Health Care System Catalonia...
Abstract Background A protocol for cervical cancer screening among sexually active women 25 to 65 years of age was introduced in 2006 Catalonia, Spain increase coverage and recommend a 3-year-interval between cytology. In addition, Human Papillomavirus (HPV) offered as triage test with diagnosis atypical squamous cells undetermined significance (ASC-US). HPV testing recommended within 3 months ASC-US diagnosis. According protocol, negative were referred regular including cytological exam...
To estimate cervical cytology coverage for the period 2008-2011 by age groups and health regions from data recorded in medical records of women attending centers within Catalan national system.The used to were obtained primary care information system. This was anonymous included age, center, date, results cytological smears a total 2,292,564 aged 15 years or more.A 758,690 performed 595,868 women. Among 25-65 years, estimated 32.4% assigned population 40.8% attended. Geographical variation...
Background The COVID-19 pandemic led to a national lockdown and the interruption of all cancer preventive services, including cervical screening. We aimed assess impact on opportunistic screening participation, abnormal cytology (ASCUS+) prevalence interval in 2020 2021 within Public Health System Catalonia, Spain. Methods Individual data HPV testing women aged 25–65 from 2014 were retrieved Information for Primary Care Services (SISAP). Time-series regression models used estimate expected...
This field note presents the conclusions and recommendations made at meeting 'How to reduce social inequalities in cancer screening programmes?' held XXVI School of Public Health Mahon (Menorca, Spain). Participants developed based on experiences population-based programmes (breast colorectal) opportunistic (cervical). The focused four main areas (information systems, evaluation quality, research, interventions): inclusion variables an individual level health information systems;...
HPV screening has been shown to be more cost-effective than cytology under most scenarios. Furthermore, it should offered only in organized programmes with good quality assurance mechanisms. This study analyses the comparative cost of current policy opportunistic vs. a hypothetical programme based on primary screening. Total cervical cancer expenditure was defined as sum three elements: (i) direct (medical and non-medical) costs, obtained from calibrated Markov model natural history cancer;...
Abstract Introduction Cervical cytology is a well‐stablished cervical cancer screening method. However, due to the anatomical continuity of genital tract, it can also detect signs endometrial disease. Our aim was estimate sensitivity in detection and prognosis large population over 30‐year period academic tertiary hospital Spain. Methodology We performed search for women diagnosed with from 1990 2020, who were surgically treated had previous result. Information Technologies Department...