A5001249310- Chronic Lymphocytic Leukemia Research
- Cervical Cancer and HPV Research
- Polyomavirus and related diseases
- Hepatitis B Virus Studies
- Lymphoma Diagnosis and Treatment
- Acute Lymphoblastic Leukemia research
- Viral-associated cancers and disorders
- Cancer Risks and Factors
- Global Cancer Incidence and Screening
- Metabolism, Diabetes, and Cancer
- Menopause: Health Impacts and Treatments
- Molecular Biology Techniques and Applications
- Full-Duplex Wireless Communications
- Plant Virus Research Studies
- Genital Health and Disease
- Vaccine Coverage and Hesitancy
- Vitamin C and Antioxidants Research
- Gestational Diabetes Research and Management
- Congenital Heart Disease Studies
- Traumatic Brain Injury and Neurovascular Disturbances
- Helicobacter pylori-related gastroenterology studies
- Maternal and Neonatal Healthcare
- Multiple and Secondary Primary Cancers
- Reproductive tract infections research
- Occupational and environmental lung diseases
Institut d'Investigació Biomédica de Bellvitge
2011-2024
Institut Català d'Oncologia
2012-2024
Instituto Nacional de Perinatología
2023-2024
Centre International de Recherche sur le Cancer
2016-2022
Universitat Pompeu Fabra
2015
Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública
2015
Johns Hopkins University
2012
Diet is a modifiable risk factor for several neoplasms but evidence chronic lymphocytic leukemia (CLL) sparse. Previous studies examining the association between single-food items and CLL have yielded mixed results, while few been conducted on overall diet, reporting inconclusive findings. This study aimed to evaluate adherence three dietary patterns in multicase-control (MCC-Spain) study. Anthropometric, sociodemographic, medical information was collected 369 cases 1605 controls. Three...
Background Menopausal hormone therapy (HT) has shown benefits for women; however, associated drawbacks (i.e. risks, costs, fears) have currently determined its low use.
An infectious etiology for bladder cancer has long been suspected. Merkel cell virus (MCV), BKV and JCV polyomaviruses are possible causative agents but data remain scarce. Therefore, we evaluated the seroresponse to these three in association with risk. 1,135 incident subjects from five Spanish regions 982 hospital controls matched by sex, age region were included. 99% of cases urothelial-cell carcinomas. Antibody response against MCV, was measured enzyme immunoassay using...
This study aims to describe time trends in and patterns of use hormonal contraception postmenopausal hormone therapy identify factors associated with their among Spanish women.We performed a cross-sectional analysis using data from 1,954 population controls (aged 24-85 y) 12 provinces Spain who were enrolled the Multi Case-Control (2007-2013). Data collected questionnaire conducted face-to-face by trained personnel. We information on sociodemographic factors, lifestyle, sleep patterns,...
Chronic lymphocytic leukemia (CLL) has few known modifiable risk factors. Recently, circadian disruption been proposed as a potential contributor to lymphoid neoplasms' etiology. Serum melatonin levels have found be significantly lower in CLL subjects compared with healthy controls, and also, prognosis related alterations the molecular signaling. We performed first investigation of an association between night shift work 321 incident cases 1728 population‐based controls five areas Spain....
To outline the design of a clinical trial to evaluate impact HPV vaccination as part hrHPV-based primary screening program extend intervals.
Human papillomavirus-vaccinated cohorts, irrespective of age, will likely reduce their subsequent screening requirements, thus opening opportunities for global cost reduction and program sustainability. The determinants uptake completion a 3-dose human papillomavirus vaccination by adult women in European context were estimated.
Chronic lymphocytic leukemia (CLL) is the most common in adults Western countries. Its etiology largely unknown but increasing incidence rates observed worldwide suggest that lifestyle and environmental factors such as diet might play a role development of CLL. Hence, we hypothesized consumption ultra-processed food drinks (UPF) be associated with Data from Spanish population-based case-control study (MCC-Spain study) including 230 CLL cases (recruited within three years diagnosis) 1634...
Incidence rates of lymphoma are usually higher in men than women, and oestrogens may protect against lymphoma. We evaluated occupational exposure to endocrine disrupting chemicals (EDCs) among 2457 controls 2178 incident cases subtypes from the European Epilymph study. Over 30 years EDCs compared no was associated with a 24% increased risk mature B-cell neoplasms (P-trend=0.02). Associations were observed men, but not women. Prolonged disruptors seems be moderately some subtypes.
Individuals with a history of traumatic brain injury (TBI) are at increased risk for number disorders, including Alzheimer's disease, Parkinson's and chronic encephalopathy. However, mediators the long-term morbidity uncertain. We conducted multi-site, prospective trial in TBI patients (∼18 years post-TBI) living 24-h care environments local controls without head injury. Inability to give informed consent was exclusionary participation. A total 41 individuals (17 moderate-severe TBI, 24...
Introduction−−Serum pepsinogen tests for gastric cancer screening have been debated decades. We assessed the performance of two assays with or without gastrin-17 detection different precancerous lesions alone as a composite endpoint in Latvian cohort. Methods−−Within intervention arm GISTAR population-based study, participants abnormal values by ELISA latex-agglutination tests, and subset subjects all normal biomarker were referred upper endoscopy biopsies. Performance biomarkers, corrected...
Abstract Background: Merkel cell polyomavirus (MCV) has been identified as the cause of carcinoma. The increased incidence chronic lymphocytic leukemia in cancer cohorts and lymphotropic properties virus suggest a possible viral association with lymphomagenesis. To investigate this potential role, we explored seroreactivity against MCV VP1 capsids within Epilymph case–control study Spain. Methods: Serum samples from 468 incident lymphomas, categorized into up to 11 entities, 522 controls...
We aimed to study the association between occupational exposure pesticides and chronic lymphocytic leukemia (CLL) in Spain. Occupational (four insecticides, four herbicides two fungicides) was evaluated using a job-exposure matrix for Spanish population (MatEmESp) among 302 CLL cases 1567 controls five regions of Spain, 2010–2013. Cumulative scores (CES) were obtained by summing across exposed jobs product prevalence, intensity duration each active substance. Principal components analysis...
Background The COVID-19 pandemic led to a national lockdown and the interruption of all cancer preventive services, including cervical screening. We aimed assess impact on opportunistic screening participation, abnormal cytology (ASCUS+) prevalence interval in 2020 2021 within Public Health System Catalonia, Spain. Methods Individual data HPV testing women aged 25–65 from 2014 were retrieved Information for Primary Care Services (SISAP). Time-series regression models used estimate expected...
Merkel cell polyomavirus (MCPyV) has been suspected to cause chronic lymphocytic leukaemia (CLL) but previous data are inconsistent. We measured seroreactivities of nine polyomaviruses (MCPyV, BKPyV, JCPyV, LPyV, KIPyV, WUPyV, HPyV-6, HPyV-7 and TSPyV) in 359 CLL cases 370 controls using bead-based multiplex serology technology. additionally tested two herpesviruses (HSV-1 CMV). Associations between disease viral were assessed logistic regression. All human viruses showed high...
Chronic inflammation plays a role in the development of chronic lymphocytic leukaemia (CLL), and diet might modulate inflammation. This study aims to evaluate association between dietary inflammatory index (DII®) CLL. A total 366 CLL cases 1643 controls Spanish multicase-control (MCC) Spain were included. The potential was assessed using energy-adjusted (E-DII) based on 30 items from validated semi-quantitative food frequency questionnaire. Odds ratios (OR) 95% confidence intervals (CI)...