A5075085196- Glycosylation and Glycoproteins Research
- Monoclonal and Polyclonal Antibodies Research
- Galectins and Cancer Biology
- Blood groups and transfusion
- Pharmaceutical studies and practices
- Immune Response and Inflammation
- Multiple Sclerosis Research Studies
- Porphyrin and Phthalocyanine Chemistry
- Photodynamic Therapy Research Studies
- Nanoplatforms for cancer theranostics
- Pain Management and Treatment
- Antiplatelet Therapy and Cardiovascular Diseases
- Hormonal Regulation and Hypertension
- Protease and Inhibitor Mechanisms
University of Rijeka
2022-2024
Friedrich-Alexander-Universität Erlangen-Nürnberg
2024
Science Research Laboratory
2023
Genos (Croatia)
2023
Coronary artery disease (CAD) is the most common cardiovascular (CVD), and previous studies have shown a significant association between N-glycosylation, highly regulated posttranslational modification, development of atherosclerotic plaques. Our aim was to determine whether N-glycome immunoglobulin G (IgG) associated with CAD, as N-glycans are known alter effector functions IgG, which may enhance inflammatory response in CAD. Therefore, this study, we isolated IgG from subjects coronary...
Atrial fibrillation is a disease with complex pathophysiology, whose occurrence and persistence are caused not only by aberrant electrical signaling in the heart, but development of susceptible heart substrate. These changes, such as accumulation adipose tissue interstitial fibrosis, characterized presence inflammation. N-glycans have shown great promise biomarkers different diseases, specifically those involving inflammatory changes. To assess changes N-glycosylation plasma proteins IgG...
The essential role of immunoglobulin G (IgG) in immune system regulation and combatting infectious diseases cannot be fully recognized without an understanding the changes its
Abstract Glycans are an essential structural component of Immunoglobulin G (IgG) that modulate its structure and function. However, regulatory mechanisms behind this complex posttranslational modification not well known. Previous genome-wide association studies (GWAS) identified 29 genomic regions involved in regulation IgG glycosylation, but only a few were functionally validated. One the key functional features glycosylation is addition galactose (galactosylation). We performed GWAS...
Aging | doi:10.18632/aging.205106. Azra Frkatović-Hodžić, Anika Mijakovac, Karlo MiÅ¡kec, Arina Nostaeva, Sodbo Z. Sharapov, Arianna Landini, Toomas Haller, Erik van den Akker, Sapna Sharma, Rafael R. C. Cuadrat, Massimo Mangino, Yong Li, Toma Keser, Najda Rudman, Tamara Štambuk, Maja Pučić-Baković, Irena Trbojević-Akmačić, Ivan Gudelj, Jerko Tea Pribić, Barbara Radovani, Petra Tominac, Krista Fischer, Marian Beekman, Manfred Wuhrer, Christian Gieger, Matthias B. Schulze, Clemens...