A5101480147- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- Long-Term Effects of COVID-19
- Respiratory Support and Mechanisms
- Sepsis Diagnosis and Treatment
- Renal function and acid-base balance
- COVID-19 and healthcare impacts
- Liver Disease and Transplantation
- Asthma and respiratory diseases
- Neuroscience of respiration and sleep
- COVID-19 epidemiological studies
- Hepatitis C virus research
- SARS-CoV-2 detection and testing
- Nephrotoxicity and Medicinal Plants
- Cancer-related molecular mechanisms research
- Immune responses and vaccinations
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Heme Oxygenase-1 and Carbon Monoxide
- Immune cells in cancer
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Inflammation biomarkers and pathways
- Infectious Encephalopathies and Encephalitis
- Muscle Physiology and Disorders
- Thermal Regulation in Medicine
- Inflammasome and immune disorders
Beijing YouAn Hospital
2021-2025
Capital Medical University
2013-2025
Beijing Chao-Yang Hospital
2016-2022
Beijing Chaoyang Emergency Medical Center
2020
Beijing Institute of Neurosurgery
2020
Yang Hospital
2020
// Qian Wang 1 , Lei Yang 3 Xin Hu Yuliang Jiang Yizhang Zhe Liu Jian Tao Wen Yingmin Ma 2 Guangyu An Guosheng Feng Department of Oncology, Affiliated Beijing Chaoyang Hospital, Capital Medical University, 100020, China Respiratory Medicine, Research Center, Correspondence to: Feng, email: fengguoshengcyh@163.com An, anguangyucyh@163.com Ma, mayingmincyh@163.com Keywords: long non-coding RNA, NNT-AS1, colorectal cancer, MAPK/Erk, biomarker Received: April 17, 2016 Accepted: November 21,...
There is still limited research on the prognostic value of Presepsin as a biomarker for predicting outcome COVID-19 patients. Additionally, combined predictive with clinical scoring systems and inflammation markers disease prognosis lacking.
Background: Research on biomarkers associated with the severity and adverse prognosis of COVID-19 can be beneficial for improving patient outcomes. However, there is limited research role soluble TREM-1 (sTREM-1) in predicting patients. Methods: A total 115 patients admitted to emergency department Beijing Youan Hospital from February May 2023 were included study. Demographic information, laboratory measurements, blood samples sTREM-1 levels collected upon admission. Results: Our study found...
Abstract Background Septic-acute respiratory distress syndrome (ARDS), characterized by the acute lung injury (ALI) secondary to aberrant systemic inflammatory response, has high morbidity and mortality. Despite increased understanding of ALI pathogenesis, therapies prevent dysfunction underlying disorder remain elusive. The density lipoprotein (HDL) critical protective effects in sepsis its a manifested contribution septic organ failure. However, adverse changes HDL composition function...
Epidermal growth factor (EGF), basic fibroblast (bFGF), the AA and BB isoforms of platelet-derived (PDGF) vascular endothelial (VEGF) are involved in pathogenesis airway inflammation asthma. In present study, associations between asthmatic phenotypes expression levels these mediators induced sputum serum were investigated. A total 62 patients divided into eosinophilic or neutrophilic by cytological classification sputum. addition, classified according to lung function (FEV1/FVC >70% FEV1/FVC...
Background Lianhuaqingwen (LHQW), a traditional Chinese medicine comprised of 13 herbal extracts renowned for their robust heat-clearing and detoxifying properties, has gained widespread utilization in China but yet to garner similar recognition abroad. It is believed exhibit efficacy ameliorating symptoms individuals afflicted with coronavirus disease 2019 (COVID-19). However, the precise impact LHQW on viral shedding (VS), particularly context mild or asymptomatic infections caused by...
The current study investigated the clinical manifestations and outcomes of different age groups patients with overseas imported COVID-19. In total, 53 COVID-19 admitted to designated Beijing Xiaotangshan Hospital between March 16 April 15 2020 were included. Based on percentage disease aggravation during hospital stay according CT, divided into two groups: ≤40 years (group A; n = 41) >40 B; 12). demographic data, epidemiological history, courses, potential complications, symptoms, lab...
Acute respiratory distress syndrome (ARDS) is characterized by acute lung injury (ALI) secondary to an excessive alveolar inflammatory response. Reticulocalbin 3 (Rcn3) endoplasmic reticulum (ER) lumen protein in the secretory pathway. We previously reported indispensable role of Rcn3 type II epithelial cells (AECIIs) during development and repair process. In present study, we further observed a marked induction epithelium LPS-induced ALI. vitro (MLE-12) consistently exhibited significant...
This cross-sectional study assesses changes in numbers of pediatric outpatient visits for notifiable infectious diseases acquired through droplet transmission, contact or both after implementation coronavirus disease 2019 (COVID-19)–related public health measures during the COVID-19 outbreak Beijing, China.
Abstract This study compared the differences in clinical manifestations, treatment courses and turnover between mild moderate coronavirus disease 2019 (COVID-19). Clinical data of patients with imported COVID-19 admitted to Beijing Xiaotangshan Designated Hospital March 15 April 30, 2020, were retrospectively analysed. A total 53 included, 21 32 cases. Compared group, group showed significant breathing frequency, lymphocyte count, neutrophil percentage, neutrophil/lymphocyte ratio,...
To examine the levels of 1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero phosphatidylcholine (POVPC) and 1-palmitoyl-2-glutaroyl-sn-glycero-phosphatidylcholine (PGPC) (the oxidized phosphatidylcholines) in HDL during course sepsis to evaluate their prognostic value.This prospective cohort pilot study enrolled 25 septic patients 10 healthy subjects from 2020 2021. The HDLs were extracted patient plasmas at day 1, 3 7 after onset (total 81 plasma samples). These then subjected examining POVPC PGPC by...
Purpose: Anti-viral and anti-inflammatory therapies were effective in altering virus repletion immune dysregulation Coronavirus Disease 2019 (COVID-19) patients. This study aimed to explore the effect of combination therapy on disease progression a real-world setting. Patients Methods: A total 836 patients confirmed with SARS-CoV-2 infection participated from 15 November 25 December 2022 at Beijing Youan Hospital, Capital Medical University. prospective cohort was implemented investigate...
Fungal sensitisation is closely associated with asthma; however, the correlation between fungi and asthma severity remains unclear. The aim of this study was to investigate in 100 patients due fungal non-fungal allergens. A total outpatients inpatients were selected from 2010 2011 divided into three groups (mild, moderate severe) according their clinical manifestations, lung function results treatment situations. Enzyme-linked immunosorbent assay (ELISA) used detect levels specific...
Abstract Venous thromboembolism (VTE) is an important postoperative complication. We investigated and analyzed the current inguinal hernia treatment methods occurrence of early VTE in Chinese adults. This study involved data for patients with hospitalized 58 general hospitals mainland China from January 1st, 2017 to December 31st, 2017. Data were retrospectively using a questionnaire. After inputting cleaning, we stratified statistically patients' Caprini scores create high-, middle-,...
Aims: The aim of the study was to explore functional and structural changes diaphragm underlying mechanisms in response 12 or 24 weeks cigarette smoke (CS) exposure rats. Materials Methods: Rats were exposed CS develop a COPD model rats room air served as control group. randomly divided into four groups: CS12W, CON12W, CS24W, CON24W. Pulmonary function, lung histopathology, contractile properties ultrastructure muscle examined these transcriptomic profiling further compared between by RNA...
The aim of this study was to analyse changes in the lymphocyte subgroups non-small cell lung cancer (NSCLC) patients before and during four cycles chemotherapy.NSCLC (n = 32) who were undergoing their initial chemotherapy or had finished final ≥ three months ago enrolled. divided into demographic subgroups. Lymphocyte 13) examined via flow cytometry (9 time points).NSCLC exhibited overall decreases chemotherapy. Most increased slightly second cycle but decreased afterwards compared with...
Abstract Background With the measles vaccine coverage rate gradually increasing, adult patients’ epidemiological and clinical characteristics have changed. Aims To analyze of patients in Beijing Youan Hospital. Methods We retrospectively reviewed electronic medical records 818 diagnosed with at Hospital between June 2010 October 2021. divided all hospitalized into two demographics groups, using 14 years age as cut-off. Results Of inpatients, 110 (74.83%) were aged 20–40. There was an overall...
For the distinct immune/inflammatory responses from Omicron variant infection, this study aimed to investigate diagnostic efficacy of systemic inflammatory indicators and clinical corticosteroids on in-hospital mortality among COVID-19 patients.Under a retrospective cohort study, 1081 patients were recruited Beijing Youan Hospital, Capital Medical University between November 16, 2022 January 30, 2023. We chose neutrophil-to-lymphocyte ratio (NLR), CRP-to-lymphocyte (CLR), CRP-to-albumin...