Guohong Li

ORCID: 0000-0003-3408-0187
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About
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Research Areas
  • Lung Cancer Diagnosis and Treatment
  • Traditional Chinese Medicine Studies
  • Atherosclerosis and Cardiovascular Diseases
  • Fungal Biology and Applications
  • Adipokines, Inflammation, and Metabolic Diseases
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Diabetic Foot Ulcer Assessment and Management
  • Mesenchymal stem cell research
  • Salivary Gland Tumors Diagnosis and Treatment
  • Inflammatory Biomarkers in Disease Prognosis
  • Microbial Natural Products and Biosynthesis
  • Cell Adhesion Molecules Research
  • Medical Imaging Techniques and Applications
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • IgG4-Related and Inflammatory Diseases
  • Wound Healing and Treatments
  • Mosquito-borne diseases and control
  • Medicinal Plants and Neuroprotection
  • PARP inhibition in cancer therapy
  • Microbial Metabolism and Applications
  • Phytochemicals and Medicinal Plants
  • Plant and fungal interactions
  • Biological Stains and Phytochemicals
  • Traditional Chinese Medicine Analysis
  • Advanced Radiotherapy Techniques

Guangdong Provincial People's Hospital
2019-2023

Penn State Milton S. Hershey Medical Center
2019-2023

Yunnan University
2016-2021

Southern Medical University
2020

Weatherford College
2020

Children's Hospital of Capital Institute of Pediatrics
2017

Linyi People's Hospital
2016

Louisiana State University Health Sciences Center Shreveport
2008-2015

Wenzhou Medical University
2010-2015

Sun Yat-sen University
2013-2015

Background The incidence and mortality of hepatocellular carcinoma (HCC) had increased globally over the past decades. Previous studies found that transarterial chemoembolization (TACE) combined with lenvatinib also shown efficacy in unresectable HCC. We aimed to evaluate safety TACE camrelizumab treat multiple nodular large HCC (>5 cm). Materials methods Between November 2018 June 2021, we retrospectively recruited 82 patients (BCLC stage B or C a single diameter >5 Of who not...

10.1177/15330338231200320 article EN cc-by-nc Technology in Cancer Research & Treatment 2023-01-01

Withaferin A (WA), a natural product derived from Withania somnifera, has been used in traditional oriental medicines to treat neurological disorders. Recent studies have demonstrated that this compound may potential for cancer treatment and clinical trial launched test WA treating melanoma. Herein, WA's chemopreventive was tested chemically-induced skin carcinogenesis mouse model. Pathological examinations revealed significantly suppressed tumor formation. Morphological observations of the...

10.1002/mc.22423 article EN Molecular Carcinogenesis 2015-10-16

To investigate the safety and effectiveness of computed tomography (CT)-guided 125I seed implantation for locally advanced nonsmall cell lung cancer (NSCLC) after progression concurrent radiochemotherapy (CCRT). We reviewed 78 NSCLC patients who had each one cycle first-line CCRT but progressive disease identified from January 2006 to February 2015 at our institution. A total 37 with 44 lesions received CT-guided percutaneous second-line chemotherapy (group A), while 41 B). Patients in group...

10.1097/md.0000000000002249 article EN cc-by-nc Medicine 2015-12-01

Inflammatory myofibroblastic tumor (IMT) is a rare of mesenchymal origin that commonly occurs in the lung. Because its non-specific clinical and imaging features, IMT often misdiagnosed as malignant tumor. There have been few reports on head neck.To analyze computed tomography (CT) magnetic resonance (MRI) findings inflammatory tumors (IMTs) neck.Six patients with IMTs neck confirmed by histopathologic examination were analyzed retrospectively.The mean patient age was 40 years. The locations...

10.1177/0284185113500165 article EN Acta Radiologica 2013-08-22

Red cell distribution width (RDW) has been found to be a novel prognostic biomarker in patients with coronary artery disease (CAD); however, the association between RDW and risk of heart events CAD is yet fully elucidated. Thus, aim present study was determine whether an elevated associated Framingham score (FRS) CAD. Data were retrospectively collected from Affiliated Dongyang Hospital Wenzhou Medical University (Dongyang, China). The had undergone angiography their clinical data...

10.3892/etm.2015.2244 article EN Experimental and Therapeutic Medicine 2015-01-30

Studies of the EtOAc extract culture broth and methanol mycelium Stereum insigne CGMCC5.57 led to isolation one new dihydrobenzofuran (1) six known compounds (2-7). The structures were elucidated mainly by HRESIMS experiments, 1D, 2D NMR spectroscopy analysis. This is first report about chemical constitutes fungus S. insigne.

10.1080/14786419.2016.1255889 article EN Natural Product Research 2016-11-13

Trauma, surgery, and infection can cause severe inflammation. Both dysregulated inflammation intensity duration lead to significant tissue injuries, organ dysfunction, mortality, morbidity. Anti-inflammatory drugs such as steroids immunosuppressants dampen intensity, but they derail resolution, compromise normal immunity, have adverse effects. The natural regulator mesenchymal stromal cells (MSCs) high therapeutic potential because of their unique capabilities mitigate enhance accelerate...

10.7150/thno.83942 article EN cc-by Theranostics 2023-01-01

The purpose of this study was to examine the effect mental clinical nursing pathways on suicidal ideation and life quality patients with malignant tumors.Two hundred tumors were randomly divided into a group control group, 100 in each group. During treatment, received pathway care, while those given usual such as timely inspection, nurse's reactions patient's behavior, execution medical orders. Thereafter, "self-rating idea suicide scale" Karnofsky Performance Status (KPS) used compare...

10.2147/ppa.s74132 article EN cc-by-nc Patient Preference and Adherence 2014-12-01

Studies have begun to focus on the emerging function of platelets as immune and inflammatory cells that initiate accelerate vascular inflammation. Phosphoinositide 3-kinase gamma (PI3Kγ) is critically involved in a number autoimmune diseases. This study aims investigate contribution platelet PI3Kγ remodeling under flow severely reduced conditions. Mouse partial left carotid artery ligation with adoptive transfer activated, washed wild-type or PI3Kγ-/- was used model. Intima-media area,...

10.1371/journal.pone.0129265 article EN cc-by PLoS ONE 2015-06-08

Residues 221-239 of rubella virus E1 glycoprotein contain antibody neutralization domains, and the solvent-exposed charged amino acids at binding interface may be crucial for ability. However, role acid residues on epitope in peptide-antibody is unknown. To investigate single substitutions important neutralizing epitope, biolayer interferometry serological tests were performed. There are three epitope: D229, R237, H238. Substitution D229 A had no influence activity to peptide. R237 or H238 H...

10.1089/vim.2014.0021 article EN Viral Immunology 2014-09-17

6069 Background: For resectable squamous cell carcinoma of the head and neck (HNSCC), novel therapeutic approaches are still needed to improve outcomes. Neoadjuvant immunochemotherapy (NICT) is considered as a potentially effective strategy. We therefore conducted pilot phase II trial explore efficacy safety neoadjuvant camrelizumab plus nab-paclitaxel cisplatin (NeoCPC) in patients with locoregionally advanced, HNSCC. Methods: In this open-label trial, untreated HNSCC (T2‒T4, N0‒N3b, M0;...

10.1200/jco.2023.41.16_suppl.6069 article EN Journal of Clinical Oncology 2023-06-01

To further evaluate the efficacy and safety of computed tomography (CT)-guided iodine 125 (125I) brachytherapy to treat locally advanced non-small cell lung cancer (NSCLC) after progression concurrent radiochemotherapy (CCRT).This study obtained written consent from all patients was approved by our institution. From January 2006 June 2018, 210 NSCLC (progression first-line CCRT) were retrospectively recruited then divided into two groups. A total 116 given CT-guided 125I second-line...

10.2147/cmar.s313438 article EN cc-by-nc Cancer Management and Research 2021-07-01

Abstract Trauma, surgery, and infection can cause severe inflammation. Both dysregulated inflammation intensity duration lead to significant tissue injuries, organ dysfunction, mortality, morbidity. Anti-inflammatory drugs such as steroids immunosuppressants dampen intensity, but they derail resolution, compromise normal immunity, have adverse effects. The natural regulator mesenchymal stromal cells (MSCs) high therapeutic potential because of their unique capabilities mitigate enhance...

10.1101/2022.11.19.517148 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2022-11-19
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