A5103248874- Dysphagia Assessment and Management
- Tracheal and airway disorders
- Esophageal and GI Pathology
- Child Nutrition and Feeding Issues
- Oral microbiology and periodontitis research
- Dental Health and Care Utilization
- Voice and Speech Disorders
- Salivary Gland Disorders and Functions
- Pancreatic and Hepatic Oncology Research
- Diverticular Disease and Complications
- Pelvic floor disorders treatments
- Anorectal Disease Treatments and Outcomes
- Nutrition and Health in Aging
- Medicinal plant effects and applications
- Bone health and treatments
- Biological Activity of Diterpenoids and Biflavonoids
- Pancreatitis Pathology and Treatment
- Advanced Glycation End Products research
- Pharmacological Effects of Medicinal Plants
- Biochemical effects in animals
- HIV/AIDS oral health manifestations
- Dementia and Cognitive Impairment Research
- Tendon Structure and Treatment
- Phagocytosis and Immune Regulation
- Bone Metabolism and Diseases
Osaka University
2024-2025
Kyushu Dental University
2015-2024
Ono Clinic
2023
Osaka International Cancer Institute
2020-2022
Kameda Medical Center
2014-2017
Fujita Health University Nanakuri Memorial Hospital
2011-2017
Fujita Health University Hospital
2009-2017
Fujita Health University
2002-2015
Suntory (Japan)
2003-2012
Universidade Estadual Paulista (Unesp)
2005
The methanol-soluble fraction from a Chinese natural medicine Hoveniae Semen Seu Fructus, the seed and fruit of Hovenia dulcis THUNB. (Rhamnaceae) was found to show an inhibitory effect on alcohol-induced muscular relaxation protective activity D-galactosamine/lipopolysaccharide or carbon tetrachloride-induced liver injury. Through bioassay-guided separation using traction performance test, three new dihydrofravonols named hovenitins I, II, III were isolated Fructus together with four known...
Abstract Background Oral care is important in preventing aspiration pneumonia older adults. However, it not clear what kind of oral can reduce the number bacteria saliva. The purposes this study are to clarify whether there a relationship between plaque amounts and salivary bacterial counts, how dispersed into cavity by brushing be reduced. Methods First, saliva samples were collected from 10 healthy adult volunteers after 30 h unbrushing thorough brushing, total count was determined...
Abstract Introduction Since the needs for dental care among older adults in Japan are expected to increase future, this study aimed examine influence of ageism students and clinical trainees on attitude towards care. Materials Methods In 2022, we conducted a questionnaire survey 9th‐, 11th‐semester first‐year enrolled at Kyushu Dental University, using Japanese version Ageism Scale Students (ASDS‐J), Fraboni (FSA‐J). Questions intention provide adults, relationships with living were also...
Nakagawa K, Matsuo Shibata S, Inamoto Y, Ito Abe Ishibashi N, Fujii W, Saitoh E. Efficacy of a novel training food based on the process model feeding for mastication and swallowing ― preliminary study in elderly individuals living at residential facility ―. Jpn J Compr Rehabil Sci 2014; 5: 72-78. Purpose: We examined validity safety newly developed chew-swallow managing (CSM) as material chewing swallowing. Methods: Twenty-three (mean age: 82.8 ± 8.6 years) who followed regular diet were...
Chondrogenesis is strictly regulated by several factors, including cytokines, hormones, and extracellular matrix proteins. Mouse teratocarcinoma-derived lineage cells, differentiate into chondrocytes in the presence of insulin. Although ascorbic acid promotes chondrogenic differentiation, detailed regulative mechanisms underlying its role chondrogenesis remain unclear. Therefore, this study, we evaluated effects on insulin-induced differentiation ATDC5 cells intracellular signaling. The...
ABSTRACT Osteoclasts derived from hematopoietic stem cells express immunoreceptors on their cell surface. Previously, we showed that the β‐glucan curdlan suppressed osteoclastogenesis via binding to dectin‐1, a pattern recognition receptor. Curdlan negatively regulates osteoclast differentiation and bone resorption capacity by suppressing expression of nuclear factor activated T 1 (NFATc1), master for differentiation, in dectin‐1‐dependent manner; however, mechanism involved this process has...
Background: Fusel oil has been reported to have undesirable side effects such as hangover. However, the relationship between fusel and hangover investigated insufficiently. In this study, we of their ingredients contained in alcoholic beverages by using animal models. Methods: Ethanol were simultaneously administered Suncus murinus , emetic responses observed for 60 min. mice immediately after intake saccharin solution; on next day, mouse's solution was measured. Results: The volatile...
This study examined hyoid movement during sequential swallowing and evaluated the relationship among trajectory patterns, types based on laryngeal penetration. Twelve healthy adults underwent videofluorography swallowing. Each swallow was classified into two types: opened vestibule after (i-Segmental type) closed (i-Continuous type). participant's type by same method. We analyzed two-dimensional movements of hyoid, trajectories were three patterns: moved in anterosuperior direction onset...
In recent years, magnesium hydroxide has been widely studied due to its bioactivity and biocompatibility. The bactericidal effects of nanoparticles on oral bacteria have also reported. Therefore, in this study, we investigated the biological inflammatory responses induced by periodontopathic bacteria. Macrophage-like cells, namely J774.1 were treated with LPS derived from Aggregatibacter actinomycetemcomitans two different sizes (NM80/NM300) evaluate their response. Statistical analysis was...
Abstract Background Clarifying how tongue pressure in convalescent stroke patients affects oral condition and activities of daily living (ADL) is important for developing rehabilitation programs care to reacquire ADL. Objective To clarify associated with status, ADL, nutritional status patients. Methods Sixty‐eight aged 77.9 ± 10.0 years participated. The Japanese version the Oral Health Assessment Tool was used evaluate status. Data such as ADL index functional independence measure (FIM),...
咀嚼嚥下の評価法の確立のため,健常成人10名を対象として,4食物条件下で咀嚼が嚥下反射開始前の食塊位置および嚥下時間経過に及ぼす影響を嚥下造影検査を用いて検討した.液体命令嚥下に比し全咀嚼条件で食塊先端位置の中~下咽頭への到達率が高く,食塊進入には咀嚼の存在が一義的に関与し,食物形態はそれを修飾する役割を担うと思われた.混合咀嚼条件では食塊は全例で嚥下前に中~下咽頭へ到達しており,信頼性の高い負荷法といえた.液体を含む咀嚼嚥下では,下咽頭到達が高率で下咽頭通過時間も長く,誤嚥防止の観点から興味深い所見であった.咀嚼嚥下は命令嚥下とは別様式であり「食べる」機能の評価と位置づけられた.
Shibata S, Kagaya H, Tanaka Fujii W, Nakagawa K, Matsuo Abe Ishibashi N, Inamoto Y, Saitoh E. Efficacy of a novel training food based on the process model feeding for mastication and swallowing: A study among dysphagia patients. Jpn J Compr Rehabil Sci 2017; 8: 82-87.
We used functional near-infrared spectroscopy (fNIRS) to measure cerebral blood flow during oral care in a patient with persistent disturbance of consciousness. experienced that frontal area increased care, suggesting may have potential role rehabilitation for the brain.
Tanaka T, Kagaya H, Ozeki Y, Fujii W, Iida Shibata S, Tomita Ishiguro Ota K, Saitoh E. Revised classification of aspiration before, during, and after the swallow its reliability. Jpn J Compr Rehabil Sci 2016; 7: 51-54.
Fujii W, Kondo I, Baba M, Saitoh E, Shibata S, Okada Onogi K, Mizutani H: Examination of chew swallow in healthy elderly persons: Does the position leading edge bolus pharynx change with increasing age? Jpn J Compr Rehabil Sci 2011; 2: 48-53Objective: To determine whether aging influences during as identified using videofluorography (VF).Methods: Subjects comprising 53 individuals (35 men and 18 women; mean age 54.5 ± 19.3 years range 25-89 years), were subdivided into 4 groups: young...