A5018851554- Natural Antidiabetic Agents Studies
- Ethnobotanical and Medicinal Plants Studies
- Photochromic and Fluorescence Chemistry
- Porphyrin and Phthalocyanine Chemistry
- Synthesis and Characterization of Heterocyclic Compounds
- Synthesis and biological activity
- Phytochemicals and Medicinal Plants
- Essential Oils and Antimicrobial Activity
- Synthesis and Biological Evaluation
- Medicinal Plants and Neuroprotection
- Synthesis and Reactions of Organic Compounds
- Natural product bioactivities and synthesis
- Phytochemistry and Biological Activities
- Synthesis of heterocyclic compounds
- Polydiacetylene-based materials and applications
- Organic Chemistry Cycloaddition Reactions
- Natural Products and Biological Research
- Advances in Cucurbitaceae Research
- Medicinal Plant Research
- Botanical Research and Applications
- Piperaceae Chemical and Biological Studies
- Alkaloids: synthesis and pharmacology
- Psidium guajava Extracts and Applications
- Metabolomics and Mass Spectrometry Studies
- vaccines and immunoinformatics approaches
University of Chittagong
2012-2024
Universiti Teknologi Petronas
2018
Yokohama National University
2010
Saga University
2004-2005
Marburg virus disease (MVD) caused by the (MARV) generally appears with flu-like symptoms and leads to severe hemorrhagic fever. It spreads via direct contact infected individuals or animals. Despite being considered be less threatening in terms of appearances number patients, high fatality rate this pathogenic is a major concern. Until now, no vaccine has been developed combat deadly virus. Therefore, vaccination for necessary reduce its mortality. Our current investigation focuses on...
Abstract This research describes an investigation of the antipyretic and hepatoprotective properties both a crude organic extract various subfractions ethnomedicinal plant Tinospora crispa , using appropriate animal models. In attempt to identify potential lead compounds, in silico experiments were utilized. Antipyretic activity was assessed via Brewer's yeast‐induced pyrexia method, while effects evaluated carbon tetrachloride (CCl 4 )‐induced model. A computer‐aided prediction spectra for...
Because of their superior antibacterial and pharmacokinetic capabilities, many nucleoside-based esters show potential against microorganisms, may be used as pharmacological agents to address multidrug-resistant pathogenic problems. In this study, several aliphatic aromatic groups were inserted synthesize various 5'-O-decanoyluridine (2-5) 5'-O-lauroyluridine derivatives (6-7) for antimicrobial, in silico computational, POM (Petra/Osiris/Molinspiration). The chemical structures the...
A bisthienylethene with hitherto unprecedented facial chirality imposed by a triethyleneglycol bridge on thiophene ring was synthesized and its photochromic closure shown to occur 100% diastereoselectivity upon UV-light irradiation.
A new N-acetylsulfanilylation series of uridine have been synthesized in good yield using direct acylation method and afforded the 5'-O-N-acetylsulfanilyluridine. In order to obtain newer products, 5'-O-N-acetylsulfanilyluridine derivative was further transformed a 2',3'-di-O-acyl derivatives containing wide variety functionalities single molecular framework. The chemical structures newly compounds were confirmed on basis their FTIR, 1H-NMR spectroscopy, physicochemical properties elemental...
Abstract Background The Bangladeshi rural and hilly areas people have long tradition to use various medicinal plants for treating different diseases. That’s why, the crude methanolic leaf extract of Ardisia solanacea with its fractions (petroleum ether, carbon tetrachloride, n-hexane chloroform fractions) were subjected investigate bioactivities in swiss albino mice; namely analgesic, CNS, Oral hypoglycemic activities, while in-vitro evaluation cytotoxicity. Methods Central nervous system...
Abstract Background Schizophrenia (SCZ) is an incurable neuropsychiatric disorder generally described by impaired social behavior and altered recognition of reality. For the first time, this study explored serum levels antioxidants (vitamin A, E, C), malondialdehyde (MDA), macro‐minerals (calcium, potassium, sodium), trace elements (zinc, iron, selenium) in Bangladeshi patients with SCZ thereby, discovering any pathophysiological correlation. Methods This case‐controlled evaluated 63 as...
Byttneria pilosa , a flowering plant from the Malvaceae family traditionally used to treat ailments such as boils and scabies, is here investigated for its potential health benefits. The study focused on evaluating antioxidant antidiabetic properties in vitro well vivo anxiolytic antidepressant activities of methanol extract B. leaf (MEBP). employed various assays evaluate activity, including 2, 2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging, reducing power capacity, quantification...
Abstract Dithia‐(dithienylethena)phane derivatives, composed of dithienylethene moieties and benzene bridges, were synthesized by a coupling reaction the corresponding bis(chloromethyl)benzene with bis(mercaptomethyl)dithienylethene under high‐dilution conditions. The products exhibit photochromic properties upon irradiation ultraviolet visible light. photocyclization cycloreversion quantum yields determined, relationship between yield distance reactive carbon atoms phane derivatives...
Introduction: Inflammation is a major cause of arthritis. Since the conventional medicines used for treatment this disease have many side effects, herbal remedies can be proved to effective in case. So, present study was aimed at investigating quantitative detection phytochemicals, screening vivo anti-inflammatory and possible anti-arthritic activities crude methanol extracts traditional medicinal plant Macropanax dispermus leaves (MDML) stem barks (MDMS). Methods: Quantitative phytochemical...
Abstract Background Macropanax dispermus is traditionally used to treat various diseases by ethnic people. The present research reports the pharmacological properties with phytochemical profiling of crude extracts M. leaves (MDML), its n-hexane (MDHL), carbon tetrachloride (MDTL), chloroform (MDCL), ethyl acetate (MDEL), and aqueous (MDAL) fractions, methanol stem barks (MDMS). in vitro thrombolytic activity was done on human erythrocytes whereas cytotoxic brine shrimp lethality assay. vivo...
Since plant-based natural drugs are widely accepted in modern times and possess numerous pharmacological effects with an extensive therapeutic range, ethnomedicinal plant native to Bangladesh was selected investigate for investigation of its various effects.
Introduction: Macropanax dispermus is an ethnomedicinal plant, which has been shown to have pharmacological effects against inflammation. Inflammation also associated with diabetic-related complications. In addition, the indigenous people used this plant cure numerous digestive system disorders. These uses inspired current research focus on determining biological potential of crude methanol extract its leaves (MDML) and stem barks (MDMS) morbid diseases such as diarrhea, helminthiasis,...
This research investigated the qualitative screening of phytochemicals, anxiolytic and cytotoxic potentials crude methanol extracts leaves (MEL) stem (MES) Ocimum basilicum Linn. var. pilosum (Willd.) Benth is a new variant sweet basil herb. For solvent extraction process, was selected due to its ability solubilize both polar non-polar plant constituents. Phytochemical analysis carried out by using established methods. The activity assessed on Swiss albino mice hole board apparatus,...
The current investigation aimed to explore the various pharmacological properties of methanol extracts Merremia vitifolia (Burm.f.) Hallier f. leaves (MEMV). Phytochemical analysis was performed following established procedures. Using hole board device, anxiolytic action measured. oral glucose tolerance test (OGTT) used evaluate hypoglycemic activity and castor oil-induced diarrhea method employed antidiarrheal in Swiss albino mice. Utilizing brine shrimp lethality assay (BSLA), cytotoxicity...
Nature has always blessed humanity with numerous means of remedy for treating a wide range diseases. Since different parts Calamus rotang L. have several ethnopharmacological activities, including CNS depressant and anthelmintic action, its crude methanol extract leaves was used to investigate anxiolytic, cytotoxic, activities. The selected because it could vast phytoconstituents. anti-anxiety activities CRME were investigated on the Swiss albino mice model through hole board elevated plus...