A5101548204- Ethnobotanical and Medicinal Plants Studies
- Essential Oils and Antimicrobial Activity
- Neuroinflammation and Neurodegeneration Mechanisms
- Natural Antidiabetic Agents Studies
- Phytochemistry and Biological Activities
- Cardiovascular Function and Risk Factors
- Neurological Disease Mechanisms and Treatments
- Pregnancy and preeclampsia studies
- Adipose Tissue and Metabolism
- Psidium guajava Extracts and Applications
- Congenital heart defects research
- Neuropeptides and Animal Physiology
- Medicinal Plants and Neuroprotection
- Phytochemicals and Medicinal Plants
- Pharmacology and Obesity Treatment
- Piperaceae Chemical and Biological Studies
- Sesquiterpenes and Asteraceae Studies
- Fetal and Pediatric Neurological Disorders
- Pregnancy-related medical research
- Effects of Environmental Stressors on Livestock
- Advanced Glycation End Products research
- Natural product bioactivities and synthesis
- Magnesium in Health and Disease
- Moringa oleifera research and applications
- Phytochemistry and biological activity of medicinal plants
University of Chittagong
2018-2024
Massachusetts General Hospital
2017-2022
Bangladesh College of Physicians and Surgeons
2022
Harvard University
2017-2021
Sher-e-Bangla Agricultural University
2017
Texas Tech University Health Sciences Center
2015
Texas Tech University
2015
BRAC University
2014
Tokyo University of Agriculture and Technology
2010
University of Dhaka
2010
Ischemic stroke is one of the leading causes mortality and morbidity in world effective neuroprotectants are yet to be developed. Recent studies have demonstrated excellent neuroprotective effects a bivalent enkephalin opioid agonist, biphalin multiple models.The purpose this study evaluate novel multifunctional enkephalin-fentanyl agonists, LYS436, LYS739 LYS416 for their potential using vitro vivo ischemic models compare effect that biphalin.In general, all non-selective agonists...
The present study describes the ethnobotanical, phytochemical, and toxicological evaluations of Xanthium strumarium L. growing in Bangladesh. In toxicity evaluation on rats, methanol extract seedlings showed mortality, while both seedling mature plant extracts raised serum alanine transaminase aspartate values produced significant abnormalities histopathology liver kidney rats. On other hand, aqueous soluble fraction (LC50 = 0.352 µg/mL) crude 0.656 demonstrated brine shrimp lethality...
Abstract Background The Bangladeshi rural and hilly areas people have long tradition to use various medicinal plants for treating different diseases. That’s why, the crude methanolic leaf extract of Ardisia solanacea with its fractions (petroleum ether, carbon tetrachloride, n-hexane chloroform fractions) were subjected investigate bioactivities in swiss albino mice; namely analgesic, CNS, Oral hypoglycemic activities, while in-vitro evaluation cytotoxicity. Methods Central nervous system...
Despite considerable research on exercise-induced neuroplasticity in the brain, a major ongoing challenge translating findings from animal studies to humans is that clinical and preclinical settings employ very different techniques.Here we aim bridge this divide by using diffusion tensor imaging MRI (DTI), an advanced technique commonly applied human studies, longitudinal exercise study with mice.Wild-type mice were exercised voluntary free-wheel running, scans at baseline after four weeks...
Neuregulin (NRG)1 - ErbB receptor signaling has been shown to play an important role in the biological function of peripheral microvascular endothelial cells. However, little is known about how NRG1/ErbB impacts brain and blood-brain barrier (BBB) properties. pathways are affected by injury; when trauma was induced mice a controlled cortical impact model, ErbB3 gene expression reduced greater extent than that other NRG1 receptors. This finding suggests ErbB3-mediated processes may be...
Introduction: Inflammation is a major cause of arthritis. Since the conventional medicines used for treatment this disease have many side effects, herbal remedies can be proved to effective in case. So, present study was aimed at investigating quantitative detection phytochemicals, screening vivo anti-inflammatory and possible anti-arthritic activities crude methanol extracts traditional medicinal plant Macropanax dispermus leaves (MDML) stem barks (MDMS). Methods: Quantitative phytochemical...
Cynodon dactylon (Poacae) is a well known traditional plant used as folk remedy in treatment of many symptoms and diseases like cramps, measles, tumors, wounds, warts, fever rheumatic affections. In this study, the antimicrobial activity crude extract from three different extraction (hot cold aqueous extraction, methanol extraction) was investigated against some gram positive bacteria (Staphylococcus epidermidis, Bacillus cereus) negative (Escherichia coli, Pseudomonas aeroginosa, Salmonella...
Nowadays, myocardial infarction (MI) is one of the major causes death in developing countries including Bangladesh. Trace elements and macro-minerals play an important role pathogenesis MI. This study aimed to determine trace Bangladeshi patients with case control included 74 MI healthy individuals as group. Flame atomic absorption spectroscopy graphite furnace were used measure serum hint factors (Zn, Fe, Se) macro minerals (Ca, K, Na). Statistical evaluation was done using independent...
Both exercise-induced molecular mechanisms and physiological cardiac remodeling have been previously studied on a whole heart level. However, the regional microstructural tissue effects of these in yet to be spatially linked further elucidated. We show exercised mice that expression CITED4, transcriptional co-regulator necessary for cardioprotection, is regionally heterogenous with preferential significant increases lateral wall compared sedentary mice. Concordantly this same region, heart's...
DOI: 10.3329/dujps.v8i2.6034 Dhaka Univ. J. Pharm. Sci. 8(2): 173-175, 2009 (December)
Abstract Background Macropanax dispermus is traditionally used to treat various diseases by ethnic people. The present research reports the pharmacological properties with phytochemical profiling of crude extracts M. leaves (MDML), its n-hexane (MDHL), carbon tetrachloride (MDTL), chloroform (MDCL), ethyl acetate (MDEL), and aqueous (MDAL) fractions, methanol stem barks (MDMS). in vitro thrombolytic activity was done on human erythrocytes whereas cytotoxic brine shrimp lethality assay. vivo...
Efficient and accurate detection of estrus correct time artificial insemination are essential for sustainable dairy farms. Therefore, this study was carried out to monitor oestrus by observing vaginal electrical impedance (VEI) in post-partum cows. Eighteen cows with 19-139 days were included study. Daily VEI values measured heat detector®. Lower resistance (VER) recorded during oestrus. VER 210-240 ? might be indicative The day difference between two successive lower or higher VER waves...
Since plant-based natural drugs are widely accepted in modern times and possess numerous pharmacological effects with an extensive therapeutic range, ethnomedicinal plant native to Bangladesh was selected investigate for investigation of its various effects.