A5066338295- Essential Oils and Antimicrobial Activity
- Phytochemistry and Biological Activities
- Traditional and Medicinal Uses of Annonaceae
- Natural product bioactivities and synthesis
- Phytochemistry Medicinal Plant Applications
- Plant biochemistry and biosynthesis
- Insect Pest Control Strategies
- Phytochemicals and Antioxidant Activities
- Trypanosoma species research and implications
- Phytochemical compounds biological activities
- Bee Products Chemical Analysis
- Natural Compound Pharmacology Studies
- Research on Leishmaniasis Studies
- Allelopathy and phytotoxic interactions
- African Botany and Ecology Studies
- Plant tissue culture and regeneration
- Ethnobotanical and Medicinal Plants Studies
- Cholinesterase and Neurodegenerative Diseases
- Chemical synthesis and alkaloids
- Phytochemistry and Bioactivity Studies
- Botanical Research and Chemistry
- Bioactive Natural Diterpenoids Research
- Bioactive natural compounds
- Plant Pathogens and Fungal Diseases
- Medicinal Plants and Neuroprotection
Universidade Federal de Sergipe
2011-2025
Universidade Federal de São Carlos
2003-2016
Universidade Federal do Ceará
2012
Universidade Estadual de Campinas (UNICAMP)
2001-2003
Medicinal plants are one of the most important sources drugs used in pharmaceutical industry. Among traditional medicinal plants, Lippia gracilis Schauer (Verbenaceae) had been for several purposes Brazilian northeastern. In this study, leaf essential oil (EO) L. was prepared using hydrodistillation. Followed by GC–MS analysis, its composition characterized presence thymol (55.50%), as major constituent. The effects EO on cell proliferation and apoptosis induction were investigated HepG2...
Abstract Introduction The species Lantana camara is used in folk medicine. biological activities of this medicinal plant are attributable to the presence various derivatives triterpenoids and phenolic compounds present its preparations, indicating excellent economic potential. Objective In study, operational conditions ultrasound‐assisted extraction (UAE) microwave‐assisted (MAE) were optimized using Box–Behnken design improve total content (TPC) recovered hydroethanolic extracts L. leaves....
Plants are promising sources of new bioactive compounds. The aim this study was to investigate the cytotoxic potential nine plants found in Brazil. species studied were: <i>Annona pickelii</i> Diels (Annonaceae), salzmannii</i> A. DC. <i>Guatteria blepharophylla</i> Mart. hispida</i> (R. E. Fr.) Erkens & Maas <i>Hancornia speciosa</i> Gomes (Apocynaceae), <i>Jatropha curcas</i> L. (Euphorbiaceae), <i>Kielmeyera rugosa</i> Choisy (Clusiaceae), <i>Lippia gracilis</i> Schauer (Verbenaceae), and...
The antioxidant capacity by oxygen radical absorbance (ORAC)-FL method and antimicrobial activity using the broth microdilution of aporphinoids (liriodenine 1, anonaine 2 asimilobine 3) other alkaloids (reticuline 4 cleistopholine 5) isolated from bark Annona salzmannii A. DC. (Annonaceae) were evaluated. For activity, most active alkaloid was with ORAC value 2.09 relative trolox equivalents. some showed significant minimal inhibitory concentration (MIC) values in range 25-100 µg mL(-1)....
The essential oils from the leaves of Annona salzmannii and A. pickelii (Annonaceae) growing in Sergipe, northeastern region Brazil, were obtained by hydrodistillation using a Clevenger-type apparatus, analyzed GC/MS GC/FID. Thirty-four compounds identified oil twenty-seven that pickelii; sesquiterpenes predominated both oils. Bicyclogermacrene (20.3%), ( E)-caryophyllene (19.9%), δ-cadinene (15.3%), α-copaene (10.0%), allo-aromadendrene (5.7%) main components salzmannii, bicyclogermacrene...
► Leaves of Annona pickelii yielded terpenes, lignans, and isoquinoline alkaloids. Isolated compounds are reported for the first time. Isoquinoline alkaloids chemotaxonomic marker genus . Furofuranic type lignans predominant in leaves A. The NMR data nornuciferine ( 8 ) were revised.
The essential oil from the leaves of Annona vepretorun was obtained by hydrodistillation using a Clevenger-type apparatus and analyzed GC-MS GC-FID. Eighteen compounds representing 98.1% crude were identified. major identified bicyclogermacrene (43.7%), spathulenol (11.4%), alpha-felandrene (10.0%), alpha-pinene (7.1%), (E)-beta-ocimene (6.8%), germacrene D (5.8%), p-cymene (4.2%). trypanocidal activity against Trypanosoma cruzi epimastigote forms, as well as, antimicrobial antioxidant...
► Bark of Annona salzmannii yielded sesquiterpenes, steroids, and isoquinoline alkaloids. Isoquinoline alkaloids are the chemotaxonomic marker genus . The NMR data for reticuline ( 12 ) were revised. Selin-11-en-4 α -ol 3 is reported first time in
Phytochemical investigation of the hexane extract from stem Xylopia laevigata led to isolation ent-kaurane diterpenoids, ent-kaur-16-en-19-oic acid, 4-epi-kaurenic ent-16β-hydroxy-17-acetoxy-kauran-19-al, ent-3β-hydroxy-kaur-16-en-19-oic and ent-16β,17-dihydroxy-kauran-19-oic as well spathulenol a mixture β-sitosterol, stigmasterol campesterol. The identification compounds was performed on basis spectrometric methods including GC-MS, IR, 1D 2D NMR. Potent larvicidal activity against Aedes...
"Aspectos químicos e biológicos do gênero Lippia enfatizando gracilis Schauer". Esta revisão apresenta um estudo sobre os principais constituintes aspectos de espécies a Schauer. O Verbenaceae) possui aproximadamente 200 ervas, arbustos pequenas árvores, cujos maiores centros dispersão se encontram em países das Américas Sul Central, como também territórios da África tropical. Inúmeras são usadas na medicina popular para o tratamento resfriados, gripes, bronquites tosse. As pesquisas...
Pelargonium graveolens l'Herit AND Lippia alba (Mill) N. E. Brown AGAINST Spodoptera frugiperda (J.E. Smith).Insecticidal activity of essential oils graveolens, and compounds geraniol, linalool, 1,8-cineole, limonene, carvone, citral Azamax ® were evaluated against frugiperda.Topical application assay showed oil P. has acute toxicity larvae (third instar) with LD 50 1.13 µg/mg per insect 90 2.56 insect.Three L. also exhibited insecticidal ranging from 1.20 to 1.56 2.60 3.75 insect.Geraniol,...
Dioscorea villosa (DV) has been used in Brazil as an alternative medicine to attenuate menopause symptoms, well for the treatment of joint pain and rheumatoid arthritis. In spite popular use DV various disorders, there are limited scientific data regarding safety aspects this herb. regard, we carried out evaluated both antinociceptive anti-inflammatory activities experimental models assess toxic effects acute (single dose) subchronic (30 days) oral administration dry extract rodents. The LC...
Research to identify plant bioactive compounds led the evolution of extraction methods. This study optimized ultrasound-assisted (UAE) and microwave-assisted (MAE) extract flavonoids Croton grewioides Baill. species contributing characterize polar profile understand antioxidant potential these constituents. The use experimental design statistical treatments enabled determination ideal conditions for each technique. extracts five accessions C. were obtained under analyzed using ultra...
“Aspectos químicos e biológicos do gênero Lippia enfatizando gracilis Schauer”. Esta revisão apresenta um estudo sobre os principais constituintes aspectos de espécies a Schauer. O Verbenaceae) possui aproximadamente 200 ervas, arbustos pequenas árvores, cujos maiores centros dispersão se encontram em países das Américas Sul Central, como também territórios da África tropical. Inúmeras são usadas na medicina popular para o tratamento resfriados, gripes, bronquites tosse. As pesquisas...
Our taxonomic interest in the Neoraputia stimulated an investigation of N. paraensis searching for alkaloids. Fractions were monitored by ¹H NMR and ESI-MS/MS only those which showed features anthranilate alkaloids flavonoids absent previous investigations examined. Stems afforded flindersine, skimmianine, 8-methoxyflindersine dictamnine; leaves yielded 3',4',7,8-tetramethoxy-5,6-(2",2"-dimethylpyrano)-flavone, 3',4',5,7,8-pentamethoxyflavone, 5-hydroxy-3',4',6,7-tetramethoxyflavone,...
The known anti-protozoal activity of flavonoids has stimulated the testing other derivatives from natural and synthetic sources.As part our efforts to find potential lead compounds, a number isolated Neoraputia paraensis, N. magnifica, Murraya paniculata, (Rutaceae), Lonchocarpus montanus, L. latifolius, subglaucescens, atropurpureus, campestris, Deguelia hatschbachii (Leguminosae), dibenzoylmethanes subglaucescens analogues were tested for in-vitro against chloroquine-sensitive Plasmodium...
The biological activity of seven extracts from leaves different Jatropha curcas L (Euphorbiaceae) accessions was evaluated on Spodoptera frugiperda. Methanol were incorporated into an artificial diet and offered to the larval stage S. parameters length pupal stages, mortality total cycle stage, weight pupae. EMB showed best result for at 60.00 56.67%, compared with control, respectively. Hexane partition methanol extract PM-14 allowed identification phytosterols, phytol n-alkanols.