A5015971723- Thyroid Cancer Diagnosis and Treatment
- Salivary Gland Disorders and Functions
- Signaling Pathways in Disease
- Medical Imaging Techniques and Applications
- Thyroid Disorders and Treatments
- Radiopharmaceutical Chemistry and Applications
- Neuroblastoma Research and Treatments
- Ferroptosis and cancer prognosis
- Pediatric Hepatobiliary Diseases and Treatments
- Salivary Gland Tumors Diagnosis and Treatment
- Head and Neck Anomalies
- Healthcare Systems and Public Health
- Head and Neck Cancer Studies
- Radiation Dose and Imaging
- Thyroid and Parathyroid Surgery
- Liver Disease Diagnosis and Treatment
- Cancer, Lipids, and Metabolism
- Caveolin-1 and cellular processes
- melanin and skin pigmentation
- Erythrocyte Function and Pathophysiology
- Radiology practices and education
- Inflammatory Biomarkers in Disease Prognosis
- Radiomics and Machine Learning in Medical Imaging
- Genetic Associations and Epidemiology
- Hepatocellular Carcinoma Treatment and Prognosis
First Affiliated Hospital of GuangXi Medical University
2016-2024
Guangxi Medical University
2016-2024
Jiangsu University
2022-2024
Health Commission of Anhui Province
2021
Purpose Ischemic penumbra is the main therapeutic target for acute ischemic stroke. The aim in this study to investigate potential serum biomarkers of that could fulfill a complementary role stroke clinical decision‐making process. Experimental Design An established focal cerebral ischemia model applied rats. Using isobaric tags relative and absolute quantitation combined with liquid chromatography‐tandem mass spectrometry, global expression profiles proteins tissue from rats subjected...
Aim: To explore the association between preoperative hemoglobin-to-red cell distribution width ratio (HRR), platelet-to-monocyte or monocyte-to-high-density lipoprotein and risk of breast cancer. Materials & methods: The clinical data 226 patients with cancer were retrospectively analyzed compared 199 healthy controls by multivariate logistic regression analysis. Results: Multivariate analysis revealed that HRR (p < 0.001) independent predictors lower was associated longer hospitalization,...
Background Thyroid disease (TD) is a prominent endocrine disorder that raises global health concerns; however, its comorbidity patterns remain unclear. Objective This study aims to apply network-based method comprehensively analyze the of TD using large-scale real-world data. Methods In this retrospective observational study, we extracted comorbidities adult patients with from both private and public data sets. All were identified ICD-10 (International Classification Diseases, 10th Revision)...
Background Anoikis is intricately associated with the malignant progression of cancer. Thyroid cancer (THCA) most common endocrine tumor, metastasis closely related to treatment response and prognosis THCA. Hence, it imperative comprehensively identify predictive prognostic genes novel molecular targets for effective THCA therapy. Methods Differential expression analysis weighted gene co-expression network (WGCNA) were utilized mine differentially expressed anoikis-related (DE-ARGs). Then,...
To optimize the performance of hepatobiliary scintigraphy (HS) for suspected biliary atresia (BA) using a timesaving and semiquantitative method without loss in diagnostic accuracy.A retrospective analysis 185 patients with persistent jaundice who underwent surgery were included. According to surgical evaluation pathological diagnosis, divided into BA group (99 cases) an infant hepatitis syndrome (IHS) (86 cases). 99mTc-labeled diethylacetanilide-iminodiacetic acid (99mTc-EHIDA) HS was...
Abstract Background Thyroid cancer (TC) is the most common endocrine malignancy; basigin (also known as BSG) plays a crucial role in tumor cell invasion, metastasis, and angiogenesis. This study was designed to identify change of BSG expression TC its possible potential mechanism. Methods The levels were demonstrated using data collected from in-house immunohistochemical (IHC), RNA-sequencing (RNA-seq), microarrays, literatures. Integrated analysis performed determined comprehensively. Gene...
Abstract Background Hashimoto’s thyroiditis (HT) may cause salivary dysfunction in patients resulting xerostomia, but little is known about changes function with no obvious dry mouth symptoms. In this study we assessed women HT, who had not experienced xerostomia and, for the first time, evaluated effects of thyroid auto-antibodies on function. Methods Sixty consecutive subjects were included, comprising 32 (mean age, 36 ± 12 years) diagnosed HT accompanied by differentiated cancer (DTC)...
Aims : Leucine zipper downregulated in cancer 1 (LDOC1) inhibits tumor growth several cancers. However, the expression and function of LDOC1 hepatocellular carcinoma (HCC) remain unknown. In this study, we aimed to investigate how influenced progression biological functions HCC. Methods The transcription levels were determined using GEPIA UALCAN online databases a real-time polymerase chain reaction. Western blot immunohistochemistry used validate protein LDOC1. Kaplan-Meier Plotter was...
Abstract Background Thyroid cancer (TC) is the most common endocrine malignancy, Basigin (also known as BSG) plays a crucial role in tumor cell invasion, metastasis, and angiogenesis. This study was designed to identify change of BSG expression TC its possible potential mechanism. Methods The levels were demonstrated using data collected from in-house immunohistochemical (IHC), RNA-sequencing (RNA-seq), microarrays literatures. Integrated analysis performed determined comprehensively. gene...
A 46-year-old asymptomatic woman with a newly detected large pulmonary mass was admitted to our hospital. An ultrasonography-guided needle biopsy performed based on suspicion of malignancy, and an ectopic goiter confirmed pathologically. Laboratory findings were unremarkable, except that thyroid function tests suggested subclinical hyperthyroidism. 131I whole-body scintigraphy SPECT/CT further revealed intense radioiodine uptake in the mass, mediastinal nodule, gland. diagnosis normally...
Objective To investigate the diagnostic value of residual ratio and 99Tcm-pertechnetate uptake at 10 min (UR10 min) in patients with Sjogren′s syndrome (SS). Methods The retrospective study included 94 cases SS (9 males, 85 females; average age (48±13) years) 60 non-SS (control group; 14 46 females, (46±13) years). All underwent salivary gland scintigraphy. According to parotid gland, were divided into 3 groups: group A including 15 normal 7 mild injury, B 56 moderate C 16 severe...
<sec> <title>BACKGROUND</title> Thyroid disease (TD) is a prominent endocrine disorder and an increasing worldwide public health concern, yet the phenotypic comorbidity pattern of TD patients remains unclear. </sec> <title>OBJECTIVE</title> We aimed to use network-based method systematically analyze provide complete picture patterns for patients. <title>METHODS</title> In this retrospective observational study, we extracted comorbidities nearly 20 thousand adults diagnosed with from tertiary...