A5100628609- Pancreatic and Hepatic Oncology Research
- Neuroendocrine Tumor Research Advances
- Gastrointestinal disorders and treatments
- Cancer Immunotherapy and Biomarkers
- Gastric Cancer Management and Outcomes
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Pediatric Hepatobiliary Diseases and Treatments
- Aortic aneurysm repair treatments
- Organ Transplantation Techniques and Outcomes
- Aortic Disease and Treatment Approaches
- Autophagy in Disease and Therapy
- Ferroptosis and cancer prognosis
- Pancreatic function and diabetes
- Lung Cancer Research Studies
- Liver Diseases and Immunity
- Mechanical Circulatory Support Devices
- Genetic and Kidney Cyst Diseases
- Head and Neck Surgical Oncology
- Esophageal Cancer Research and Treatment
- Gastrointestinal motility and disorders
- Pancreatitis Pathology and Treatment
- Liver physiology and pathology
- Lipoproteins and Cardiovascular Health
- Bacterial Identification and Susceptibility Testing
- Meta-analysis and systematic reviews
Jiangsu University
2025
Lanzhou University
2015-2024
Lanzhou University Second Hospital
2015-2024
Kaiser Permanente
2023
First Affiliated Hospital of Xi'an Jiaotong University
2023
Sun Yat-sen Memorial Hospital
2021
Sun Yat-sen University
2021
Guangdong Medical College
2021
Weifang Medical University
2021
Guangxi Medical University
2018-2020
Atherogenic index of plasma (AIP) has been reported to be associated with cardiovascular diseases. However no study yet systematically evaluated the association between AIP and obesity its advantage in prediction compared conventional lipid components. A total 6465 participants aged over 30 years were included this study. Blood components including triglyceride (TG), cholesterol (TC), high-density lipoprotein (HDL-C) low-density (LDL-C) measured, was calculated as log10(TG/HDL-C). Pearson...
A broad histomorphologic spectrum of ampullary carcinomas Vater make a reproducible histologic classification difficult. Using cytokeratin immunohistochemistry, we present new and analyze their clinical significance. Fifty-five invasive Vater's ampulla were histologically classified into pancreaticobiliary, intestinal, other types. Serial sections all carcinoma specimens additionally stained with antibodies to cytokeratins (CK7, CK20), apomucins (MUC1, MUC2, MUC5AC), CEA, CA19-9, Ki67, p53....
Rationale: Follicular tumors with uncertain malignant potential of the thyroid are a new classification in World Health Organization (2017). Only few cases evaluating value ultrasound combined pathological examination diagnosing follicular have been reported recent decades. Patient concerns: A retrospective analysis was performed on 18 patients who underwent preoperative ultrasonography and were confirmed by operation pathology our hospital from January 2019 to November 2024. Ultrasonic...
The goal was to investigate the prevalence of acute kidney injury (AKI) after total arch replacement with frozen elephant trunk procedure, which achieved by antegrade cerebral perfusion and moderate hypothermic circulatory arrest (MHCA) or deep (DHCA) among patients type A aortic dissection.Overall, 627 adult dissection who underwent from January 2013 until December 2016 at Fuwai Hospital were divided into DHCA (14.1-20.0°C) MHCA (20.1-28.0°C) groups. Postoperative AKI as primary outcome...
To examine the significance of anti-catabolism in renal hypertrophy, cellular autophagy was investigated by electron microscopic morphometry proximal tubular cells (PTCs) outer cortex rat kidney after induction diabetes mellitus streptozotocin (STZ) and unilateral nephrectomy. Adult male Sprague-Dawley rats were divided into three groups killed retrograde perfusion fixation, 1, 2 3 days (group D; n=24), nephrectomy N; n=24) combined treatment DN; n=24). Untreated, agematched litter mates...
4511 Background: Patients (pts) with advanced esophageal squamous cell carcinoma (ESCC) refractory to first-line chemotherapy have limited treatment options. The study aims evaluate the efficacy and safety of sintilimab, a PD-1 inhibitor, versus in these pts, explore predictive value PD-L1 neutrophil-to-lymphocyte ratio (NLR) on sintilimab. Methods: open-label, multi-center phase 2 trial (NCT03116152) enrolled ESCC pts chemotherapy, randomly assigned (1:1) them receive sintilimab (200mg,...
2514 Background: To explore the safety and synergistic anti-tumor effect of fruquintinib (a VEGFR inhibitor) in combination with sintilimab (an anti-PD-1 Ab) patients (pts) advanced colorectal cancer (CRC) other solid tumors. Methods: This is an ongoing phase Ib/II, multicenter, two-stage study. Pts variety types, including CRC, were enrolled continuously enrolling For this interim analysis, all pts analyzed for whereas only CRC efficacy. MMR status pts. Stage 1 was classical “3+3” dose...
This study aimed to investigate the association between interleukin 28B (IL28B) single nucleotide polymorphisms (SNPs) and sustained virological response (SVR) in Chinese Han patients with chronic hepatitis C (CHC) analyze correlations IL28B SNPs their personal, clinical characteristics.Altogether 631 individuals, including 297 CHC treated pegylated interferon α plus ribavirin, 14 spontaneous responders virus (HCV) 320 healthy controls were enrolled study. Two main of IL28B, rs12979860...
Objectives: Intestinal motility is impaired in acute necrotizing pancreatitis (ANP). The aim of present study was to investigate the effects octreotide on small intestinal motor function during experimentally induced ANP. Methods: l-Omithine intraperitoneally injected induce Octreotide administrated subcutaneously every 8 hours. intestine migrating myoelectrical complexes and slow waves vivo were recorded before after (24, 48, 72 hours) ANP induction. morphological alterations interstitial...
Background The impairment of facial expression recognition has become a biomarker for early identification first-episode schizophrenia, and this kind research is increasing. Aims To explore the differences in brain area activation using different degrees disgusted antipsychotic-naïve patients with schizophrenia healthy controls. Methods In study, tests were performed on 30 first-episode, (treatment group) subjects (control matched age, educational attainment gender. Functional MRI was used...
The authors aimed to clarify the incidence and risk factors of postoperative liver dysfunction (PLD) in patients undergoing total arch replacement combined with frozen elephant trunk implantation determine association PLD short-term outcomes.Data from 672 adult January 2013 until December 2016 at Fuwai Hospital were analysed retrospectively. A multivariable logistic regression model was used identify for PLD.The overall 27.5%, which associated higher in-hospital mortality (PLD 4.9% vs No...
Cystic lesions of the pancreas resembling intraductal papillary mucinous neoplasms (IPMN) have been reported to develop in an increased rate following liver transplantation and immunosuppression. The cause for this possible association is thus far elusive. We report on a 60-year-old male patient who developed extensive multicystic change entire pancreas, suspicious IPMN, under follow-up after secondary sclerosing cholangitis. A total pancreaduodenectomy with splenectomy was performed....
Congenital cysts are malformations developing from the endoderm and mesoderm of digestive respiratory system in early weeks gestation. Unilocular or multilocular dysontogenic most commonly thoracically located adjacent to trachea bronchus development an oesophageal duplication cyst wall is extremely rare. The adult usually asymptomatic incidental diagnosis. Potential symptoms include dysphagia retrosternal pain. Next endoscopy computer tomography, endoscopic ultrasonography mandatory for a...
Vulvar cancer is the fourth most common gynecologic cancer, and prognosis poor in advanced vulvar patients. Treatment for has not been satisfactory. In this report, we firstly report a FIGO IVB vulva verrucous carcinoma patient who obtained good after systemic treatment.A was admitted to hospital due her lesion persistent past 14 years. The mass widely invaded urethra, part of anus, lower third vagina, bilateral superior inferior branches pubis, internal external muscles obturator. Multiple...