A5030295081- Nutritional Studies and Diet
- Metabolomics and Mass Spectrometry Studies
- Diet and metabolism studies
- Nutrition, Genetics, and Disease
- Pancreatic function and diabetes
- Phytochemicals and Antioxidant Activities
- Diet, Metabolism, and Disease
- Nutrition and Health in Aging
- Natural Antidiabetic Agents Studies
- Consumer Attitudes and Food Labeling
- Fatty Acid Research and Health
- Infant Nutrition and Health
- Muscle metabolism and nutrition
- Biochemical Analysis and Sensing Techniques
- Gut microbiota and health
- Tea Polyphenols and Effects
- Botanical Research and Applications
- Sensory Analysis and Statistical Methods
- Magnesium in Health and Disease
- Genetically Modified Organisms Research
- Coffee research and impacts
- Lipoproteins and Cardiovascular Health
- Agriculture Sustainability and Environmental Impact
- GABA and Rice Research
- Obesity and Health Practices
Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán
2020-2025
University of Copenhagen
2018-2021
Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
2016-2020
Unité de Nutrition Humaine
2016-2020
Centre de Recherche en Nutrition Humaine d'Auvergne
2016-2020
Université Clermont Auvergne
2018
Globally, we are failing to meet numerous nutritional, health, and environmental targets linked food. Defining food composition in its full chemical quantitative diversity is central data-driven decision making for supporting nutrition sustainable diets. "Foodomics"-the application of omics-technology characterize quantify biomolecules improve wellbeing-has the potential comprehensively elucidate what food, how this varies across system, diet as an ensemble foods guides outcomes nutrition,...
Significance Statement The calcium-sensing receptor (CaSR) activates salt reabsorption through the sodium-chloride cotransporter (NCC) via WNK4-SPAK pathway. Glucose and other sugars are positive allosteric modulators of CaSR. This would be irrelevant for most cells that come into contact with glucose, except nephron segments beyond proximal tubule. Using in vitro vivo models, this work shows arrival glucose or fructose to distal modulates CaSR due a type II effect associated activation...
Excess amino acids from a protein-rich diet are mainly catabolized in the liver. However, it is still unclear to what extent gut microbiota may be involved mechanisms governing this catabolism. Therefore, aim of study was investigate whether consumption different dietary protein concentrations induces changes taxonomy microbiota, which contribute regulation hepatic acid Consumption high-protein caused overexpression HIF-1α colon and increase mitochondrial activity, creating more anaerobic...
Background: The metabolome of COVID-19 patients has been studied sparsely, with most research focusing on a limited number plasma metabolites or small cohorts. This is the first study to test saliva in comprehensive way, revealing patterns significantly linked disease and severity, highlighting saliva’s potential as non-invasive tool for pathogenesis diagnostic studies. Methods: We included 30 asymptomatic subjects no prior infection vaccination, 102 mild SARS-CoV-2 infection, 61...
Introduction Food composition databases (FCDBs) are essential resources for characterizing, documenting, and advancing scientific understanding of food quality across the entire spectrum edible biodiversity. This knowledge supports a wide range applications with societal impact spanning global system. To maximize utility data, FCDBs must adhere to criteria such as validated analytical methods, high-resolution metadata, FAIR Data Principles (Findable, Accessible, Interoperable, Reusable)....
Scope The aim is to identify breastmilk components associated with fecal concentration of SCFAs and investigate whether they differ between infants high weight gain (HW) normal (NW). Methods results Breastmilk samples are collected from mother–infant dyads HW ( n = 11) NW 15) at 5 9 months age. profiled on ultra‐performance LC‐quadrupole TOF‐MS platform. Fecal quantified using an isotope‐labeled chemical derivatization method. Human milk oligosaccharides (HMOs) HPLC after fluorescent...
Metabolic dysfunction-associated steatotic liver disease (MASLD) is a serious health problem, and recent evidence indicates that gut microbiota plays key role in its development. It known 2-oleoyl glycerol (2-OG) produced by the associated with hepatic fibrosis, but it not whether this metabolite involved development of steatosis. The aim study was to evaluate how high-fat–sucrose diet (HFS) increases 2-OG production through dysbiosis identify modifies lipogenesis mitochondrial activity for...
Heat treatment is a widely used method for food processing, and the compounds formed by heat processes may serve as biomarkers of heated intake in nutrition studies. Therefore, we aimed to characterize differential metabolic signatures resulting from different potato products identify potential biomarkers. In randomized, controlled, crossover meal study, healthy volunteers consumed boiled rice, potatoes, two deep-fried products, chips French fries. The urine metabolome was acquired...
Coffee is a widely consumed beverage worldwide and has high content of chlorogenic acids, polyphenols, methylxanthines, volatile flavor compounds. Scientific evidence to support the beneficial health effects coffee limited, validated urinary biomarkers intake are therefore needed. We observed 23 common putative in three separate parallel intervention studies by ultra-high-performance liquid chromatography-electrospray ionization-quadrupole time-of-flight-mass spectrometry (UHPLC-ESI-QTOF-MS)...
Abstract The present study aimed to determine the prevalence of adiposity-based chronic disease (ABCD) and its association with anthropometric indices in Mexican population. A cross-sectional was conducted 514 adults seen at a clinical research unit. American Association Clinical Endocrinology/AACE/ACE criteria were used diagnose ABCD by first identifying subjects BMI ≥ 25 kg/m 2 those 23–24·9 waist circumference 80 cm women or 90 men. presence metabolic complications associated adiposity,...
Highlights•Ceramide 24:0 is the major lipid specie found in obese-diabetic Mexican subjects•Fetal exposure to high-energy diets accumulates plasma ceramide offspring.•Ceramide disrupts adipose tissue remodeling.•Ceramide mitochondria function tissue.AbstractFetal programming by increases susceptibility type 2 diabetes mellitus (T2DM2) offspring. Glucose imbalance during fetal might be associated still unknown selective species and their characterization beneficial for T2DM diagnosis...
Abstract Background The metabolome of COVID-19 patients has been studied sparsely, with most research focusing on a limited number plasma metabolites or small cohorts. This is the first study to test saliva in comprehensive way, revealing significant changes linked disease severity and highlighting potential as non-invasive diagnostic tool. Methods We included 30 asymptomatic subjects no prior infection vaccination, 102 mild SARS-CoV-2 infection, 61 hospitalized confirmed status. Saliva...