A5102960005- Cancer-related molecular mechanisms research
- Opportunistic and Delay-Tolerant Networks
- Genomics and Phylogenetic Studies
- Stock Market Forecasting Methods
- Plant and Fungal Species Descriptions
- Spinal Fractures and Fixation Techniques
- Time Series Analysis and Forecasting
- Pelvic and Acetabular Injuries
- Circular RNAs in diseases
- Energy Load and Power Forecasting
- Phonocardiography and Auscultation Techniques
- RNA modifications and cancer
- Radiomics and Machine Learning in Medical Imaging
- Age of Information Optimization
- Music and Audio Processing
- Mobile Ad Hoc Networks
- Caching and Content Delivery
- RNA Research and Splicing
- Ferroptosis and cancer prognosis
- Garlic and Onion Studies
- Forecasting Techniques and Applications
- Plant chemical constituents analysis
- Phytochemical Studies and Bioactivities
- Explainable Artificial Intelligence (XAI)
- Genetic diversity and population structure
University College London
2012-2024
State Key Laboratory of Biotherapy
2017-2024
Sichuan University
2017-2024
University of Hong Kong
2022-2023
Xian Central Hospital
2013-2019
Jining Medical University
2013-2019
National University of Defense Technology
2011
The genus Allium (Amaryllidaceae, Allioideae) is one of the largest monocotyledonous genera and it includes many economically important crops that are cultivated for consumption or medicinal uses. Recent advances in molecular phylogenetics have revolutionized our understanding taxonomy evolution. However, phylogenetic relationships some sections (such as section Daghestanica) genetic bases adaptative evolution, remain poorly understood. Here, we newly assembled six chloroplast genomes from...
Urophysa is a Chinese endemic genus comprising two species, rockii and henryi. In this study, we sequenced the complete chloroplast (cp) genomes of these species their relative Semiquilegia adoxoides. Illumina sequencing technology was used to compare sequences, elucidate intra- interspecies variations, infer phylogeny relationship with other Ranunculaceae family species. A typical quadripartite structure detected, genome size from 158,473 158,512 bp, consisting pair inverted repeats...
Lilium henrici Franchet, which belongs to the family Liliaceae, is an endangered plant native China. The wild populations of L. have been largely reduced by habitat degradation or loss. In our study, we determined whole chloroplast genome sequence for and compared its structure with other (including Nomocharis) species. a circular 152,784 bp in length. large single copy small 82,429 17,533 size, respectively, inverted repeats are 26,411 size. contains 116 different genes, including 78...
The long noncoding RNA (LncRNA) SNHG7 (small nuclear host gene 7) is a novel LncRNA and functions as an oncogene to promote tumor proliferation inhibits apoptosis in many cancers. However, the role of osteosarcoma (OS) remains be further investigated. In this study, OS tissues corresponding relative normal (n = 30) were collected determine expression OS. results indicated that high level correlated with Enneking stage, distant metastasis, short overall survival time patients. Moreover,...
Abstract Objectives Autophagy, a highly conserved lysosomal degradation process in eukaryotic cells, can digest long‐lived proteins and damaged organelles through vesicular trafficking pathways. Nowadays, mechanisms of autophagy have been gradually elucidated thus the discovery small‐molecule drugs targeting has always drawing much attention. So far, some autophagy‐related web servers available online to facilitate scientists obtain information relevant conveniently, such as HAD b, CTLPS...
Long noncoding RNA (LncRNA) containing microRNA host gene is an interesting type of LncRNA. MicroRNA-31 (miR-31)-host LncRNA (MIR31HG) have been recognized as oncogene in many cancers, but not osteosarcoma (OS). Interestingly, MIR31HG/miR-31 could regulate each other's expression certain cancer, suggesting that the role MIR31HG cancer independent miR-31. We here investigated function and potential mechanism OS.OS tissues adjacent non-tumor (n=40) were collected to determine expressions by...
Accessible game design is a key effort aimed at creating games that transcend physical and cognitive limitations. By carefully integrating series of functions strategies, designers empower players with various abilities to participate in the interactive field. Resolve visual barriers through high contrast effects, scalable fonts, alternative color dependent information. Auditory elements are accompanied by cues or subtitles ensure narrative can be understood auditory impairments. utilizing...
Abstract Long non‐coding RNAs (lncRNAs) can crucially regulate activation and transformation of cancer‐associated fibroblasts (CAFs) but have not been systematically investigated at single cell resolution. Here, by utilizing integrated single‐cell sequencing datasets, we screened the aberrantly expressed lncRNAs in CAFs, which are major component tumor microenvironment. Our findings revealed a consistent CAF‐specific downregulation Maternally Expressed Gene 3 (MEG3) expression increased MEG3...
Average nucleotide identity (ANI) is a prominent approach for rapidly classifying archaea and bacteria by recruiting both whole genomic sequences draft assemblies. To evaluate the feasibility of ANI in virus taxon demarcation, 685 poxviruses were assessed. Prior to analysis, fragment length threshold value optimized as 200 bp 98 per cent, respectively. After analysis network visualization, resulting sixty-one species (ANI rank) clustered largely consistent with groupings found National...
Introduction Immature ovarian teratomas are a type of malignant germ cell tumor composed complicated types and characterized by pathological features immature neuroectodermal tubules/rosettes. However, there is lack understanding patient-derived (PDT) at the single level. Moreover, whether stem lines derived from (CDT) can be used as models for research on PDT remains to elucidated. Methods Single-cell RNA sequencing (scRNA-seq) subsequent bioinformatic analysis was performed three samples...
Background: Tumor metastasis commonly affects pleura in advanced lung cancer and results malignant pleural effusion (MPE). MPE is related to poor prognosis, but without systematic investigation on different cell types their crosstalk at single resolution. Methods: We conducted single-cell RNA-sequencing (scRNA-seq) of patients with effusion. Next, our data were integrated 5 datasets derived from individuals under normal, non-malignant disease carcinomatous conditions. Mesothelial cells...
The Qinghai-Tibet Plateau (QTP) has been biogeographically divided into the eastern monsoonal and western continental climatic zones along 500 mm isohyet. However, this biogeographic hypothesis rarely tested using a phylogeographic approach. members of genus Allium subgenus Cyathophora coincidentally distribute across biogeographical divide. Intriguingly, fasciculatum Amerallium co-occurs in distribution range Cyathophora. To illuminate role divide on genetic divergence, we genotyped 466...
Routing in delay tolerant networks (DTN) adopts the store-carry-forward mode, and it requires nodes to forward data a cooperative way. However, may be not willing help others many applications this behavior can called as individual selfish. On other hand, often divided into different communities, same community have some social ties. Due these ties, are more one community, but others. This Note that belong than real world, phenomenon makes network overlapping communities. paper proposed...
Images taken under different camera poses are rotated or distorted, which leads to poor perception experiences. This article proposes a new framework automatically transform the images conformable view setting by assembling convolution neural networks. Specifically, referential three-dimensional ground plane is first derived from color image and novel projection mapping algorithm developed achieve automatic viewing transformation. Extensive experimental results demonstrate that proposed...
Angelica nitida is an endemic species in China. The complete chloroplast genome sequence of A. was generated by de novo assembly using whole next generation sequencing. 146,512bp length and constructed out four parts – a large single copy (LSC) region 93,298bp, small (SSC) 18,068bp two inverted repeat (IRa IRb) regions 17,573bp each. annotation predicted total 113 genes, including 80 protein-coding 29 tRNA 4 rRNA genes. Phylogenetic analysis with the reported genomes revealed that most...
The goal of stock trend prediction is to forecast future market movements for informed investment decisions. Existing methods mostly focus on predicting trends with supervised models trained extensive annotated data. However, human annotation can be resource-intensive and the data are not readily available. Inspired by impressive few-shot capability Large Language Models (LLMs), we propose using LLMs in a setting overcome scarcity labeled make more feasible investors. Previous works...