A5091794069- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Traumatic Brain Injury and Neurovascular Disturbances
- Cardiovascular and Diving-Related Complications
- Intracranial Aneurysms: Treatment and Complications
- Stroke Rehabilitation and Recovery
- Optical Imaging and Spectroscopy Techniques
- Photoacoustic and Ultrasonic Imaging
- Migraine and Headache Studies
- Vascular Malformations Diagnosis and Treatment
- Intracerebral and Subarachnoid Hemorrhage Research
- Venous Thromboembolism Diagnosis and Management
- Cerebral Venous Sinus Thrombosis
- Cardiovascular Health and Disease Prevention
- Vestibular and auditory disorders
- Angiogenesis and VEGF in Cancer
- Obstructive Sleep Apnea Research
- Ultrasound and Hyperthermia Applications
- Moyamoya disease diagnosis and treatment
- Trigeminal Neuralgia and Treatments
- Alzheimer's disease research and treatments
- Esophageal and GI Pathology
- Biomarkers in Disease Mechanisms
- Meningioma and schwannoma management
- Infrared Thermography in Medicine
Hospital de Sant Pau
2012-2025
Vall d'Hebron Institut de Recerca
2019-2023
Hebron University
2020
Vall d'Hebron Hospital Universitari
2009-2019
Hospital Universitario Ramón y Cajal
2014
Hospital Universitari Germans Trias i Pujol
2014
Hospital Universitari Arnau de Vilanova
2014
Complejo Hospitalario Universitario de Santiago
2014
Biogipuzkoa Health Research Institute
2014
University of Genoa
2005-2013
We sought to assess outcomes after endovascular treatment/therapy of acute ischemic stroke, overall and by subgroups, looked for predictors outcome.We used data from a mandatory, population-based registry that includes external monitoring completeness, which assesses reperfusion therapies consecutive patients with stroke since 2011. described subgroups (age ≤ or >80 years; onset-to-groin puncture >6 hours; anterior posterior strokes; previous IV recombinant tissue-type plasminogen activator...
Introduction The efficacy of intracranial rescue stenting (RS) following failed mechanical thrombectomy (MT) in large-vessel occlusion (LVO) stroke remains uncertain. We aimed to evaluate clinical outcomes RS patients with anterior circulation LVO unsuccessful MT. Patients and methods conducted a retrospective analysis using the Stroke Code Registry Catalonia (January 2016–March 2022), prospective, population-based registry including treated at 10 comprehensive centers. compared between who...
To prospectively evaluate longitudinal changes in white matter lesions (WMLs) migraineurs with aura, by magnetic resonance imaging (MRI), and to correlate WMLs modifications patients' clinical characteristics.Forty-one consecutive aura were followed for a mean time of 33.2 months. Patients underwent MRI at baseline follow-up evaluated cerebrovascular risk factors. Presence on was assessed two neuroradiologists.WMLs present 26 subjects (63.4%) MRI. At total 8 patients had new (19.5%). There...
Right-to-left shunt (RLS) due to patent foramen ovale is a well-established risk factor for cryptogenic stroke and highly prevalent in cases of migraine, cluster headache, obstructive apnea. It can be diagnosed by gaseous-contrast transcranial Doppler, yet small percentage it cannot done owing an insufficient temporal window. The aim the study was compare transtemporal with transoccipital approaches Doppler RLS diagnosis.We evaluated 183 subjects standard protocol diagnosis simultaneously...
Abstract Objectives The levels of circulating endothelial progenitor cells ( EPC s) in ischemic stroke have not been studied extensively and reported results are inconsistent. We aimed to investigate the time course, prognostic relevance, variables associated with counts patients at different points. Material methods prospectively 146 consecutive within first 48 h from onset symptoms (baseline). evaluated demographic data, classical vascular risk factors, treatment thrombolysis statins,...
Subjects with migraine aura (MA) have a high prevalence of white matter lesions (WMLs) on magnetic resonance imaging (MRI). Moreover, right-to-left shunt (RILES), mainly due to patent foramen ovale, is frequently associated MA. The aim this study was clarify the relationship between RILES and WML in We enrolled 87 consecutive subjects affected by Patients were screened for characteristics cerebrovascular risk factors. Transcranial Doppler used diagnose MRI T2-weighted diffusion-weighted...
Migraine with aura (MA) is associated the persistence of patent foramen ovale (PFO) in about 50% cases, and migraineurs tend to have larger shunts than controls, suggesting that right-to-left shunt (RILES) determined by PFO could play a role triggering migraine attacks. Moreover, some preliminary reports suggested closure may give relief both The aim this study was clarify if shunt-associated (SAM) has clinical features allow distinction from shunt-unrelated (SUM), prospective, multicentre,...
In this pilot study, we have evaluated bedside diffuse optical monitoring combining correlation spectroscopy and near-infrared to assess the effect of thrombolysis with an intravenous recombinant tissue plasminogen activator (rtPA) on cerebral hemodynamics in acute ischemic stroke.Frontal lobes five patients middle artery occlusion were measured bilaterally during rtPA treatment.Both ipsilesional contralesional hemispheres showed significant increases blood flow, total hemoglobin...
e6S everal studies have consistently demonstrated the capa- bility of ultrasound to enhance lysis intra-arterial thrombi in acute ischemic stroke during systemic intravenous thrombolysis with tissue plasimogen activator (tPA), an intervention also called sonothrombolysis. Material and Methods Objectives1. To quantify potential benefits sonothrombolysis stroke.2. harms Types StudiesRandomized controlled trials clear allocation concealment. ParticipantsPatients admitted hospital stroke....
Background First-pass recanalization via mechanical thrombectomy (MT) has been associated with improved clinical outcome in patients acute ischaemic stroke. The optimal approach to achieve first-pass effect (FPE) remains unclear. No study evaluated angiographic features the achievement of FPE. We aimed determine procedural approaches and signs that may predict Methods performed a prospective, multi-centre, observational FPE anterior circulation stroke treated MT between February June 2017....
Mechanical thrombectomy (MT) in ischemic stroke patients with poor prestroke conditions remains controversial. We aimed to analyze the frequency of previously disabled treated MT clinical practice, safety and response preexisting disability, patient characteristics associated a better MT.We studied all consecutive anterior circulation occlusion from January 2017 December 2019 included Codi Ictus Catalunya registry-a government-mandated, prospective, hospital-based data set. Prestroke...
<b>Background:</b> Although ultrasound-activated microbubbles (MB) accelerate clot lysis, MB activation has shown to promote blood barrier disruption and bleeding in animal models. We conducted a case–control study aimed investigate the risk of hemorrhagic transformation (HT) after MB-enhanced sonothrombolysis acute stroke. <b>Methods:</b> evaluated total 296 patients with stroke treated IV tissue plasminogen activator (tPA) <3 hours onset. One hundred eighty-eight received continuous...
Objective: The objective of the study was to compare cerebral distribution white matter lesions (WMLs) between migraine patients with different aura symptoms. Methods: Migraine (MA) were consecutively enrolled as part Shunt-Associated (SAM) study. According clinical symptoms, classified motor, aphasic, sensory, visual or vertebrobasilar. Standard and FLAIR (fluid attenuated inversion recovery) T 2 -weighted MRI sequences inspected for WMLs by three independent raters blinded data. assessed...
<b><i>Background:</i></b> Intracranial amyloid and hypertensive angiopathy have been related to impaired blood vessel function the etiology of intracerebral hemorrhage (ICH). Microbleeds (MBs) are surrogate radiological markers that associated with these underlying angiopathies. We assessed hypothesis MBs hematoma expansion (HE) in patients hyperacute ICH. <b><i>Methods:</i></b> studied spontaneous supratentorial ICH within first 6 h after...
The ultimate goal of therapeutic strategies for ischemic stroke is to reestablish the blood flow region brain. However, currently, local cerebral hemodynamics (microvascular) almost entirely inaccessible clinicians at patient bed-side, and recanalization major arteries (macrovascular) only available measure evaluate therapy, which does not always reflect conditions. Here we report case an whose microvascular oxygenation were monitored by a compact hybrid diffuse optical monitor during...
The relationship between migraine with aura and patent foramen ovale (PFO) is still debatable. We report 2 cases of attacks after diagnostic microbubble injection for contrast transcranial Doppler (cTCD), in subjects large PFO. In one case MR images, including diffusion weighted imaging apparent coefficient, performed during did not show any signal abnormality. Patients may have an attack cTCD, probably by a “non‐ischemic” mechanism.
Lumbar instability often causes clinical symptoms, and spondylolisthesis is a main factor of the low back pain. Segmental lumbar generally due to degenerative or listhesic process spine radiological imaging essential diagnose it. segmental mobility has commonly been studied by dyanamic radiographic methods. Dynamic X-rays, with maximal extension flexion tract, represents most widely used technique valid method estimate sagittal motion. Between 1998 2002 we treated 75 patients for low-grade...
The goal of this study was to evaluate the effectiveness and safety a new noncompletely occlusive net-assisted remodeling technique in which Cascade net device is used for temporary bridging intracranial aneurysms.