A5026268608- Nanoplatforms for cancer theranostics
- Nanoparticle-Based Drug Delivery
- Photodynamic Therapy Research Studies
- RNA Interference and Gene Delivery
- Extracellular vesicles in disease
- Advanced Nanomaterials in Catalysis
- Antimicrobial Peptides and Activities
- Cancer-related molecular mechanisms research
- Photoacoustic and Ultrasonic Imaging
- Inflammasome and immune disorders
- Immunotherapy and Immune Responses
- Gold and Silver Nanoparticles Synthesis and Applications
- Angiogenesis and VEGF in Cancer
- Cancer, Hypoxia, and Metabolism
- Pancreatic and Hepatic Oncology Research
- Inhalation and Respiratory Drug Delivery
- Ultrasound and Cavitation Phenomena
- Gastric Cancer Management and Outcomes
- Peptidase Inhibition and Analysis
- Mercury impact and mitigation studies
- Autophagy in Disease and Therapy
- Viral Infectious Diseases and Gene Expression in Insects
- Bone Tissue Engineering Materials
- Laser-induced spectroscopy and plasma
- Cancer Cells and Metastasis
Huazhong University of Science and Technology
2020-2025
Union Hospital
2020-2025
Hubei University
2018-2024
Ministry of Education
2016
By mimicking the RIBE machinery, we provided an indirect radiotherapy approach based on RT-MP for eradication of MPE in mice.
Photodynamic therapy (PDT) is a clinical cancer treatment modality based on the induction of therapeutic reactive oxygen species (ROS), which can trigger immunogenic cell death (ICD). With aim simultaneously improving both PDT-mediated intracellular ROS production and ICD levels, we designed serum albumin (SA)-coated boehmite ("B"; aluminum hydroxide oxide) organic-inorganic scaffold that could be loaded with chlorin e6 (Ce6), photosensitizer, honey bee venom melittin (MLT) peptide, denoted...
Polypyrrole nanoparticle (PPy) based theranostic agents for magnetic resonance imaging (MRI) guided photothermal therapy (PTT) have received increasing attention in recent years. However, the limitations of cost and biocompability still offer us opportunities to improve these agents. Considering versatile character polydopamine (PDA), PEGylated PPy@Fe3+-chelated PDA nanocomposites (PPDEs) were designed prepared an easy way. PPDE with a uniform core-shell structure could be obtained by...
Inorganic or inorganic-organic hybrid nanomaterials have great potential for applications in the biomedical fields. Biological half-life is an essential pharmacokinetic parameter these materials to function
Schematic illustration of the synthesis SILs and NIR fluorescence imaging guided SF, PDT PTT theranostic nanoplatforms.
Angiogenesis is an irreplaceable therapeutic cancer target, where anti-angiogenesis are drugs that limited by their hydrophobicity and low effects.
Pyroptosis is a programmed cell death mediated by gasdermins (GSDMs). The prognostic value of pyroptosis-related genes in different tumor types has been gradually demonstrated recently. However, the impact GSDMs expression glioma remains unclear. Here, we present comprehensive bioinformatic analysis gasdermin family member gene expression, producing model for and creating competing endogenous RNA (ceRNA) network. mRNA profiles clinical information patients were downloaded from TCGA CGGA. A...
Oncolytic virus ablation of tumor cells has the advantages high selectivity, strong immunogenicity, and low side effects. However, recognition clearance oncolytic viruses by immune system are main factors limiting their anti-tumor efficiency. As a highly biosafe modifiable vector, acrylamide can improve long-term circulation viruses. Still, it is limited in its uptake efficiency cells. Herein, we constructed an N-hydroxymethyl acrylamide-b-(N-3-aminopropyl methacrylamide)-b-DMC block...
Magnetic resonance imaging (MRI)-guided photothermal therapy (PTT) has recently attracted tremendous attention.
Phototherapy has garnered worldwide attention for its minimal invasiveness, controllability, and spatial selectivity in treating cancer. One promising approach involves the use of near-infrared dye IR780, which demonstrates both photodynamic therapy (PDT) photothermal (PTT) effects under 808 nm laser irradiation. However, this hydrophobic dye's toxicity limited tumor targeting ability severely hamper suitability cancer applications. Herein, a biocompatible nanoplatform CoOOH-IR780@BSA...
Abstract Pyroptosis is a programmed cell death process mediated by gasdermins (GSDMs). The prognostic value of pyroptosis-related genes in different tumor types has been gradually demonstrated recently. However, the impact GSDMs expression glioma remains unclear. Here, we present comprehensive bioinformatic analysis gasdermin family member gene expression, producing model for and creating competing endogenous RNA (ceRNA) network. We identify significant association between GSDMD GSDME stage,...
In this paper, with tetrabutyl titanate and isopropyl as the titanium precursors, TiO2 nanoparticles doped different amounts of N V were synthesized using sol-gel method. The mainly characterized by scanning electron microscope (SEM), X-ray diffraction (XRD), Ultraviolet-visible diffuse-reflectance spectroscopy (DRS) vis-photocatalytic activity was determined measuring rate methylene blue decolorization. results show that grain size prepared is smaller rutile transformation temperature...