A5101846246- Lung Cancer Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Lung Cancer Treatments and Mutations
- Pleural and Pulmonary Diseases
- Medical Imaging and Pathology Studies
- Trauma Management and Diagnosis
- Congenital Diaphragmatic Hernia Studies
- Tracheal and airway disorders
- Air Quality and Health Impacts
- Cardiac, Anesthesia and Surgical Outcomes
- Pneumothorax, Barotrauma, Emphysema
- Health, psychology, and well-being
- Air Quality Monitoring and Forecasting
- Reconstructive Surgery and Microvascular Techniques
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Meningioma and schwannoma management
- Diverse Scientific Research Studies
- Neurofibromatosis and Schwannoma Cases
- Pancreatic and Hepatic Oncology Research
- Occupational exposure and asthma
- Advanced X-ray and CT Imaging
- Soft tissue tumors and treatment
- Transplantation: Methods and Outcomes
- Climate Change and Health Impacts
- Cancer-related molecular mechanisms research
Chinese Academy of Medical Sciences & Peking Union Medical College
2013-2024
Beijing Aerospace General Hospital
2015-2023
Peking University
2007-2020
Peking University People's Hospital
2007-2020
Beijing Haidian Hospital
2014
Nodule evaluation is challenging and critical to diagnose multiple pulmonary nodules (MPNs). We aimed develop validate a machine learning-based model estimate the malignant probability of MPNs guide decision-making.A boosted ensemble algorithm (XGBoost) was used predict malignancy using clinicoradiologic variables 1,739 from 520 patients with at Chinese center. The (PKU-M model) trained 10-fold cross-validation in which hyperparameters were selected fine-tuned. validated compared solitary...
To study the correlation between prognosis and different sequences of pulmonary artery vein interruption during completely thoracoscopic lobectomy for early stage non-small cell lung cancer.Retrospective analysis 334 cases underwent lobectomy, which were identified as I~II cancer by pathology. They divided into three groups according to order vessel interruption: first (Group V, n = 174), A, 93), artery-vein-artery group M, 67). Their preoperative operative conditions, postoperative...
Non-small-cell lung cancer (NSCLC) is the leading cause of deaths in world and often diagnosed at an advanced stage, so it urgent to explore pathogenesis new diagnostic biomarkers. Accumulated evidences suggested that small nucleolar RNAs (snoRNAs) played a key role development progression NSCLC. To examine differential expression snoRNA profile identify snoRNAs with clinical significance adenocarcinoma (LUAD), The Cancer Genome Atlas (TCGA) LUAD RNA sequencing dataset was used investigate...
Localization of multiple small lung nodules is the technical difficulty minimally invasive operation resection. However, there are few clinical studies on preoperative localization nodules. This study was designed to evaluate value computed tomography (CT) guided microcoil for compared with single nodule before video-assisted thoracoscopic surgery (VATS).A retrospective analysis data 235 patients pulmonary performed. According whether were single, they divided into group (184 cases) and (51...
Background Postoperative hospital stay after pancreaticoduodenectomy (PD) is relatively longer than other gastrointestinal operations. The aim of the current study was to investigate risk factors associated with prolonged PD. Methods Patients who had PD at Cancer Hospital Chinese Academy Medical Sciences between December 2008 and November 2012 were selected for this retrospective study. Clinical pathological data collected analyzed. primary outcome postoperative length stay. Normal discharge...
Objective To determine the indications for primary spontaneous pneumothorax in young patients after closed drainage.Methods From Jaunary 2007 to December 2012,139 patients,who had chest tube drainage and full information by telephone follow-up,patients were divided into recurrence recurrence-free group.The possible influence factors related statistically analyzed.Results Single factor multi-factor analysis indi cated that aspect of self-factors,the edge lung X-ray independent prediction (P ＜...
Objective To assess the safety,effectiveness,indications and advantage of modified Hemi-Clamshell approach for giant anterior mediastinal tumor.Methods From Apr 2003 to May 2012,24 patients (18 males 6 females,median aged 40 years old) with tumor (average dimension:11.3 cm × 9.3 cm) were treated through approach.In operation,anterolateral thoracotomy sternum transection was performed 3rd or 4th intercostal space from midclavicular line contralateral parasternal line.Then a radical palliative...
<p>Illustration of the CADx product (RX)</p>
<p>Risk category judged by clinicians</p>
<p>ROC curves of each center in the prospective comparison cohort</p>
<p>The generalizability of PKU-M model in prediction SPNs</p>
<p>Supplementary file</p>
<p>ROC curves of each center in the independent validation cohort</p>
<p>Comparison of AUCs between PKU-M model, Brock PKU Mayo and VA model in subgroups</p>
<p>ROC curves of each center in the independent validation cohort</p>