A5040894157- SARS-CoV-2 and COVID-19 Research
- Metamaterials and Metasurfaces Applications
- Gaussian Processes and Bayesian Inference
- Statistical Methods and Bayesian Inference
- Long-Term Effects of COVID-19
- Milk Quality and Mastitis in Dairy Cows
- Probabilistic and Robust Engineering Design
- Microbial infections and disease research
- Bacteriophages and microbial interactions
- COVID-19 Clinical Research Studies
- Animal Virus Infections Studies
- Immune Response and Inflammation
- Scientific Research and Discoveries
- Acute Lymphoblastic Leukemia research
- Viral gastroenteritis research and epidemiology
- Selenium in Biological Systems
- Advanced Multi-Objective Optimization Algorithms
- Personality Traits and Psychology
- Spam and Phishing Detection
- Phytochemistry and Bioactive Compounds
- Mental Health Research Topics
- Wind and Air Flow Studies
- Drug Transport and Resistance Mechanisms
- Innovative Human-Technology Interaction
- Green IT and Sustainability
University of Exeter
2018-2025
Northeast Agricultural University
2019-2024
Chinese Academy of Sciences
2023-2024
Shanghai Institute of Materia Medica
2023-2024
Sichuan Agricultural University
2024
Nanjing University of Chinese Medicine
2024
Women's Hospital, School of Medicine, Zhejiang University
2022
First Affiliated Hospital of Guangzhou Medical University
2020
Guangzhou Medical University
2020
University of Glasgow
2015-2018
Abstract The rapid emergence of SARS-CoV-2 mutants with new phenotypic properties is a critical challenge to the control ongoing pandemic. B.1.1.7 was monitored in UK through routine testing and S-gene target failures (SGTF), comprising over 90% cases by March 2021. Now, reverse occurring: SGTF are being replaced an positive variant, which we associate B.1.617.2. Evidence from characteristics demonstrates that, following importation, B.1.617.2 transmitted locally, growing at rate higher than...
Reactive oxygen species (ROS) act as a group of signaling molecules in rice functioning regulation development and stress responses. Respiratory burst oxidase homologues (Rbohs) are key enzymes generation ROS. However, the role nine Rboh family members was not fully understood multiple disease resistance yield traits. In this study, we constructed mutants each genes detected their requirement Our results revealed that mutations five (RbohA, RbohB, RbohE, RbohH, RbohI) lead to compromised...
Computer models are used to study the real world, and often contain a large number of uncertain input parameters, produce outputs, may be expensive run need calibrating real-world observations useful for decision-making. Emulators as cheap surrogates simulator, trained on small simulations provide predictions with uncertainty at unseen inputs. In epidemiological applications, example compartmental or agent-based modelling spread infectious diseases, output is usually spatially temporally...
The primary aim of this study was to evaluate the efficacy phage against mastitis induced by drug-resistant S. aureus in a mouse model. In study, five phages—4086-1, 4086-2, 4086-3, 4086-4, and 4086-6—were isolated from milk samples secreted cows. Transmission electron microscopy showed that all phages had icosahedral heads short non-contractile tails, which are typical characteristics family Podoviridae. All these were species-specific aureus. one-step growth curve latency period (10–20...
There have been impressive advances in the physical and mathematical modelling of complex physiological systems last few decades, with potential to revolutionise personalised healthcare patient-specific evidence-based diagnosis, risk assessment treatment decision support using digital twins. However, practical progress genuine clinical impact hinge on successful model calibration, parameter estimation uncertainty quantification, which calls for novel innovative adaptions methodological...
There have been many large-scale investigations of users' mobile app launch behaviour, but all conducted on Android, even though recent reports suggest iPhones account for a third smartphones in use. We report the first analysis usage patterns iPhones. conduct reproduction study with cohort over 10,000 jailbroken iPhone users, reproducing several studies previously Android devices. find some differences, also significant similarities: e.g. communications apps are most used both platforms;...
TNFα and related inflammatory factor antibody drugs have been orchestrated for the treatment of bowel disease (IBD). However, elicited inevitable disadvantages small molecule are in an urgent need. Herein, we described discovery, design, synthesis, SAR studies from furanone glycoside compound
Necrotizing enterocolitis (NEC) is a neonatal intestinal necrotizing disease caused by various factors in newborns. Sulforaphane (SFN) has strong anti-inflammatory ability and certain protective effect on diseases.NEC common developed gastrointestinal exigency an untimely baby. SFN naturally originated isothiocyanate that beneficial effects the system.The purpose of this study to endoplasmic reticulum stress (ERS)-related NEC.The newborn mice were randomly divided into control (n = 15), NEC...
Flickr allows its users to generate galleries of "faves", i.e., pictures that they have tagged as favourite. According recent studies, the faves are predictive personality traits people attribute users. This article investigates phenomenon and shows allow one predict whether a user is perceived be above median or not with respect each Big-Five Traits (accuracy up 79\% depending on trait). The classifier - based Gaussian Processes new kernel designed for this work identify visual...
In applications of Gaussian processes (GPs) where quantification uncertainty is a strict requirement, it necessary to accurately characterize the posterior distribution over process covariance parameters. This normally done by means standard Markov chain Monte Carlo (MCMC) algorithms, which require repeated expensive calculations involving marginal likelihood. Motivated desire avoid inefficiencies MCMC algorithms rejecting considerable amount proposals, this paper develops an alternative...
Several previous approaches attempted to predict bursty topics on Twitter. Such have usually reported that the time information (e.g. topic popularity over time) of hashtag contribute most prediction topics. In this paper, we propose a novel approach use features We model as density curves described by function beta distribution with different parameters. then various predict/classify estimating parameters topics, using estimators such Gradient Decent or Likelihood Maximization. our...
Abstract Chiral responses are optical involving circular polarizations. Controlling the chiral response in a flexible way is very important manipulations. metamaterials have thus drawn enormous interest due to their designing feature. However, most of previous studies mainly realized by structure individual meta‐atom. Meanwhile, enhance response, complex design and fabrication processes typically required. Here, introducing spin‐dependent propagating surface plasmons spin‐selective...
Abstract Environmental hazard events such as extra‐tropical cyclones or windstorms that develop in the North Atlantic can cause severe societal damage. is quantified by footprint, a spatial area describing potential However, environmental hazards are never directly observed, so estimation of footprint for any given event primarily reliant on station observations (e.g., wind speed case windstorm event) and physical model hindcasts. Both data sources indirect measurements true here we present...
Abstract Herein, we compared the risk factors, clinical presentation of patients hospitalized with SARS-CoV-2, SARS-CoV, or MERS-CoV infection. The proportion male COVID-19 was higher than who SARS but lower MERS (p<0.001). More had coexisting chronic medical conditions those (p<0.001) fewer (p<0.001), and prevalence hypertension (17%) smoking history (14%) in Furthermore,the symptom fever (53%), hemoptysis (1%), diarrhea (4%) vomiting (3%) were significantly that MERS. level ALT...
In applications of Gaussian processes where quantification uncertainty is a strict requirement, it necessary to accurately characterize the posterior distribution over process covariance parameters. Normally, this done by means standard Markov chain Monte Carlo (MCMC) algorithms. Motivated issues related complexity calculating marginal likelihood that can make MCMC algorithms inefficient, paper develops an alternative inference framework based on Adaptive Multiple Importance Sampling (AMIS)....
Two-dimensional photonic circuits with high capacity are essential for a wide range of applications in next-generation information technology and optoelectronics. Here we demonstrate multi-channel spin-dependent device based on twinning crystal metamaterial. The structural symmetry material the metamaterial enable total 4 channels carrying different transverse spins because spin-momentum locking. orientation anisotropy controls propagation direction each signal, rotation E-field respect to...
Neurogenic pulmonary edema is a clinical complication caused by various central nervous system disorders.It includes variety of pathogenic factors, however, over-activation the sympathetic nerve main mechanism.The manifestations are dyspnea and hypoxemia, which may be accompanied circulatory disorder.The respiratory support therapy treatment measures.It has characteristics rapid progress high mortality, should obtained enough attention. Key words: Neurogenic edema; Pulmonary edema,
Abstract Herein, we compared the risk factors, clinical presentation of patients hospitalized with SARS-CoV-2, SARS-CoV, or MERS-CoV infection. Our data sources include PubMed, Embase, CNKI, and Ovid/Medline. The proportion male COVID-19 was higher than who SARS but lower MERS (p<0.001). More had coexisting chronic medical conditions those (p<0.001) fewer (p<0.001), prevalence hypertension (17%) smoking history (14%) in Furthermore, symptom fever (53%), hemoptysis (1%), diarrhea...