A5016412264- Aluminum Alloys Composites Properties
- Aluminum Alloy Microstructure Properties
- Microstructure and mechanical properties
- Advanced SAR Imaging Techniques
- Catalytic C–H Functionalization Methods
- Sulfur-Based Synthesis Techniques
- Radar Systems and Signal Processing
- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Radical Photochemical Reactions
- Additive Manufacturing Materials and Processes
- Direction-of-Arrival Estimation Techniques
- Epigenetics and DNA Methylation
- Genetics and Neurodevelopmental Disorders
- Cancer-related molecular mechanisms research
- High Entropy Alloys Studies
- Cyclopropane Reaction Mechanisms
- Hippo pathway signaling and YAP/TAZ
- Genomic variations and chromosomal abnormalities
- Islanding Detection in Power Systems
- Neurogenesis and neuroplasticity mechanisms
- Metallurgy and Material Forming
- RNA modifications and cancer
- Metal and Thin Film Mechanics
- Circular RNAs in diseases
Nanjing Medical University
2025
Affiliated Hospital of Southwest Medical University
2025
Southwest University of Science and Technology
2025
Shanghai Jiao Tong University
2010-2024
Hunan City University
2021-2024
East China Normal University
2021-2024
Kunming Medical University
2024
North China University of Technology
2024
North China Electric Power University
2024
Collaborative Innovation Center of Advanced Microstructures
2024
Abstract Constitutive activation of Wnt/β-catenin inhibits oligodendrocyte myelination. Tcf7l2/Tcf4, a β-catenin transcriptional partner, is required for differentiation. How Tcf7l2 modifies signalling and controls myelination remains elusive. Here we define stage-specific Tcf7l2-regulated circuitry in initiating sustaining Multistage genome occupancy analyses reveal that serially cooperates with distinct co-regulators to control lineage progression. At the differentiation onset, interacts...
A visible-light-induced highly efficient C(sp3)–H amination of ethers with amides and azoles has been presented under mild conditions via a nitrogen- carbon-centered radical coupling process. This protocol successfully utilizes 2,3-dichloro-5,6-dicyano-p-benzoquinone (DDQ) tert-butyl nitrite (TBN) as cocatalysts to deliver the aminated products aerobic conditions. Notably, developed reaction features corresponding in good yields (up 93%) wide substrate scope. The mechanistic study indicates...
Abstract Schwann cell (SC) myelination in the peripheral nervous system is essential for motor function, and uncontrolled SC proliferation occurs cancer. Here, we show that a dual role Hippo effectors TAZ YAP through modulating G-protein expression interacting with SOX10, respectively. Developmentally regulated mutagenesis indicates TAZ/YAP are critical differentiation stage-dependent manner. Genome-wide occupancy mapping transcriptome profiling reveal nuclear promote by activating cycle...
Demyelinating diseases, such as multiple sclerosis, are known to result from acute or chronic injury the myelin sheath and inadequate remyelination; however, underlying molecular mechanisms remain unclear. Here, we performed genome occupancy analysis by chromatin immunoprecipitation sequencing in oligodendrocytes response lysolecithin-induced found that Olig2 its downstream target Gpr17 critical factors regulating oligodendrocyte survival. After oligodendrocytes, was significantly...
Wire and arc additive manufacturing based on cold metal transfer (WAAM-CMT) has aroused wide public concern in recent years as one of the most advanced technologies for components with complex geometries. However, microstructure mechanical properties parts fabricated by WAAM-CMT technology mostly are intolerable engineering application should be improved necessarily. In this study, heat treatment was proposed to optimize enhance case AlSi7Mg0.6 alloy. After treatment, division between coarse...
Statins, as an important class of lipid-lowering drugs, play a key role in the prevention and treatment cardiovascular diseases. However, with their widespread use clinical practice, some adverse events have gradually emerged. In particular, hepatotoxicity associated statins has become one concerns that require sufficient attention. this study, we conducted comprehensive detailed analysis based on data US Food Drug Administration Adverse Event Reporting System database from first quarter...
Background Esomeprazole holds a significant position in the treatment of acid-related diseases. However, as with all drugs, it may also carry some potential risk adverse effects. This study aims to further evaluate safety esomeprazole for clinical use.
Carbene radical coupling reactions are rarely developed due to their high reactivity. Here, we present a distinct electrochemical one-pot difunctionalization of diazo compounds with triazoles and nucleophiles. This method represents...