A5077551578- Antimicrobial Peptides and Activities
- Potassium and Related Disorders
- Cardiac electrophysiology and arrhythmias
- Synthesis and biological activity
- Chromatography in Natural Products
- Plant Reproductive Biology
- Hemiptera Insect Studies
- Plant Molecular Biology Research
- Bone Metabolism and Diseases
- Phytochemicals and Antioxidant Activities
- Cancer Mechanisms and Therapy
- Cell Adhesion Molecules Research
- Nigella sativa pharmacological applications
- Synthesis of heterocyclic compounds
- Cynara cardunculus studies
- Vitamin K Research Studies
- Probiotics and Fermented Foods
- Phytochemistry and biological activities of Ficus species
- Aquaculture disease management and microbiota
- Pharmacogenetics and Drug Metabolism
- Pharmacological Effects of Medicinal Plants
- Polysaccharides Composition and Applications
- Bioinformatics and Genomic Networks
- Hibiscus Plant Research Studies
- Ion channel regulation and function
Taif University
2020-2024
Agricultural Genetic Engineering Research Institute
2021
Benha University
2021
Zagazig University
2021
University of Sadat City
2021
University of Liverpool
2017
Inflammation is the main cause of several autoimmune diseases, including type I diabetes, rheumatoid arthritis, bullous pemphigoid, paraneoplastic and multiple sclerosis. Currently, there an urgent demand for discovery novel anti-inflammatory drugs with potent activity but also safe long-term application. Toward this aim, present study reported design, synthesis, characterization a set 1,3-disubstituted-2-thiohydantoins derivatives. The synthesized compounds was assessed against murine...
Plant-derived bioactive compounds with promising nutritional and therapeutic attributes (phytogenics) are among the top priorities in aquaculture sector. Therefore, impact of thymol (Thy) and/or thymoquinone (ThQ) on growth, immune response antioxidant capacity, Aeromonas sobria (A. sobria) resistance Nile tilapia was investigated. Four fish groups were fed a control diet three basal diets supplemented 200 mg/kg Thy or ThQ blend both at level each. At end feeding trial (12 weeks), tilapias...
Type 2 Diabetes Mellitus (T2DM) is the most common form of diabetes in aging population. This chronic metabolic disorder has discovered many candidate genes, and KCNJ11 was one genes associated with insulin secretion pathways mediated by potassium channels. There have been limited studies on rs5210 polymorphism T2DM patients, none them conducted Saudi Arabia.The aim this study to investigate at genotyping levels gene older population Population.Based sample size design, case-control included...
The widespread use of antibiotics causes the development antibiotic-resistant bacterial strains, which have a severe impact on poultry productivity and human health. As result, research is continuing to develop safe natural antibiotic alternatives. In current study, Bacillus pumilus SA388 was isolated from chicken feces confirmed be probiotic. selected strain tested for its antimutagenic antioxidant capabilities before being employed as probiotic food supplement alternative. effect B....
In this study the effect of Gum arabic (Acacia Senegal) was systemically targeted at male fertility with two experiments, first comparing effectiveness (GA) and Tribulus terrestris (TT). For experiment, 27 adult mice Balb / c (18 females, 9 males) were divided into 3 in each group, one group had usual tap water as power, 5% (w v) GA three TT for 21 days. The results showed, number offspring more treated when compared to treated. Blood measurements testosterone showed significant increase...
The Mig10/RIAM/Lpd (MRL) adapter protein Lpd regulates actin dynamics through interactions with Scar/WAVE and Ena/VASP proteins to promote the formation of cellular protrusions stimulate invasive migration. However, ability MRL interact multiple regulators serum response factor (SRF) signalling has raised question whether employ alternative downstream mechanisms drive oncogenic processes in a context-dependent manner. Here, using Drosophila model, we show that overexpression either human or...
Recent work has implicated the actin cytoskeleton in tissue size control and tumourigenesis, but how changes dynamics contribute to hyperplastic growth is still unclear. Overexpression of Pico, only Drosophila Mig-10/RIAM/Lamellipodin adapter protein family member, been linked overgrowth via its effect on myocardin-related transcription factor (Mrtf), an F-actin sensor capable activating serum response (SRF). Transcriptional induced by acute Mrtf/SRF signalling have largely biosynthesis...
Boswellia sp. is a species of Boswellia. Burseraceae an essential conventional natural product that has received lot attention in the pharmaceutical industry recent years. The aim this study was to role on kidney and liver Balb/c mice. Different concentrations solution given 5–7 weeks old wild-type mice both sexes (n = 24) for 21 days, with control group normal water determine physiological, biochemical, haematological, (0.5%, 1%), histopathological effect 1% 5%) sp..The results showed...
This research aims to evaluate the pharmacological efficacy of aqueous spine extracts Tribulus terrestris (TT) on liver and kidney function through physiological, biochemical, haematological, histological assessments. is renowned for its therapeutic benefits in traditional medicine practices China, India, Pakistan, Sudan treating various chronic ailments. The study employed 5 weight per volume percentage (% w/v) TT spines extract. BALB/c mice, both male female, aged 4-6 weeks, were...
T2DM is a long-term metabolic disorder characterized by either the pancreas' inability to produce enough insulin or body's properly utilize it produces. The β-cell function and blood glucose homeostasis are two areas where TCF7L2 (Transcription factor 7 like 2) appears be significant candidate gene. KCNQ1 (potassium voltage-gated channel subfamily, member 1 has been discovered as susceptibility gene in Asian populations genome-wide association studies with rs2237892 polymorphism an increased...
Aim: This study was designed to assess the antibiofilm activity of quercetin on characterized S. aureus isolates. Methodology: evaluated 36 isolates, each which identified using Gram staining, culture, biochemical, and PCR assays. Isolates were cultured their biofilm production Congo red agar (CRA) plates, microtiter plate tests PCR, effects examined. Results: The CRA results revealed that eight (22.3%) isolates strongly positive for an additional 18 (50%) showed moderate capacity. remaining...