A5101782325- Gut microbiota and health
- Diet and metabolism studies
- Probiotics and Fermented Foods
- Cellular Mechanics and Interactions
- Heat shock proteins research
- Natural product bioactivities and synthesis
- Liver Disease and Transplantation
- Drug Transport and Resistance Mechanisms
- Cancer-related molecular mechanisms research
- Dietary Effects on Health
- Vitamin K Research Studies
- Genetics, Aging, and Longevity in Model Organisms
- Liver Diseases and Immunity
- Rangeland and Wildlife Management
- Coagulation and Flocculation Studies
- Lipid metabolism and biosynthesis
- Plant pathogens and resistance mechanisms
- Kruppel-like factors research
- Infectious Diseases and Tuberculosis
- Nerve injury and regeneration
- Fatty Acid Research and Health
- Traditional Chinese Medicine Analysis
- Vasculitis and related conditions
- Maternal and fetal healthcare
- Protist diversity and phylogeny
Auburn University
2019-2024
Tongji University
2022-2024
Ministry of Natural Resources
2021-2023
Jining Medical University
2023
Luohe Medical College
2023
Chinese Academy of Medical Sciences & Peking Union Medical College
2017-2022
Ministry of Water Resources of the People's Republic of China
2021-2022
Qinghai No.3 People's Hospital
2022
First Affiliated Hospital of Dalian Medical University
2021
Dalian Medical University
2021
Abstract Because of spontaneous agglomeration effect and undesirable electronic state Zr sites on the surface, zirconium (hydro)oxides generally exhibit suboptimal defluoridation capacity. Herein, a template confinement‐ligand anchoring strategy is developed by utilizing confined growth hydroxide (ZH) inside chitosan hydrogel beads (CHB) subsequent fumaric acid (fm) its surface in monodentate mononuclear coordination mode. This technique leads to uniform dispersion ultrafine fmZH (≈3.4 nm)...
Overweight and obesity are growing health problems in domestic cats, increasing the risks of insulin resistance, lipid dyscrasias, neoplasia, cardiovascular disease, decreasing longevity. The signature feline gut microbiota has not been studied at whole-genome metagenomic level. We performed shotgun sequencing fecal samples eight overweight/obese normal cats housed same research environment. obtained 271 Gbp sequences generated a 961-Mbp de novo reference contig assembly, with 1.14 million...
To evaluate whether olfactory 1/early B cell factor-associated zinc-finger protein (OAZ), a candidate lupus susceptibility gene involved in antinuclear antibody (ANA) production, plays role the regulation of cells by mesenchymal stem (MSCs).MSCs derived from bone marrow patients with systemic erythematosus (SLE) and healthy control subjects were expanded incubated small interfering RNAs specific for OAZ or nontargeting sequence. Knockdown messenger RNA levels its downstream genes was...
Abstract Background Early diagnosis of tuberculosis meningitis (TBM) remains a great challenge during clinical practice. The diagnostic efficacies cerebrospinal fluid (CSF)‐based mycobacterial growth indicator tube (MGIT) culture, modified Ziehl–Neelsen (ZN) staining, Xpert MTB/RIF, and metagenomic next‐generation sequencing (mNGS) for TBM remained elusive. Methods A total 216 adult patients with suspicious were retrospectively enrolled in this multi‐cohort study. performances MGIT, ZN mNGS...
Abstract Atherosclerosis (AS) is associated with high morbidity and mortality, thus imposing a growing burden on modern society. Herb‐derived bicyclol (BIC) versatile bioactive compound that can be used to treat AS. However, its efficacy in AS not yet described. Here, it shown BIC normalizes gut microflora dysbiosis induced by fat diet Apoe (−/−) mice. Metagenome‐wide association study analysis verifies the modulation carbohydrate‐active enzymes short‐chain fatty acid generating genes flora...
Pressure overload-induced hypertrophic remodeling is a critical pathological process leading to heart failure (HF). Suppressor of cytokine signaling-3 (SOCS3) has been demonstrated protect against cardiac hypertrophy and dysfunction, but its mechanisms are largely unknown. Using primary cardiomyocytes cardiac-specific SOCS3 knockout (SOCS3cko) or overexpression mice, we that modulation level influenced cardiomyocyte hypertrophy, apoptosis dysfunction induced by stimuli. We found glucose...
Exopolysaccharide from
Our previous work proved that sequence specific double strand RNA (dsRNA-p21) effectively activated p21 gene expression of colorectal cancer (CRC) cells and consequently suppressed CRC growth. However, efficient delivery system is a significant challenge to achieve sufficient therapy. In this study, self-assembled HA/PEI/dsRNA-p21 ternary complex (TC-dsRNA-p21) was developed for the tumor-target dsRNA-p21 into cells. Hyaluronic acid (HA) introduced shield PEI/dsRNA-p21 binary complexes...
In the originally published version of this article, images in first line bottom left panel and second upper right within Figure 1F, demonstrating ZO-1 for NCD OCLN HFD 4E, image 5B were inadvertently misplaced.The correct are shown below.
Feline obesity is common, afflicting ~25-40% of domestic cats. Obese cats are predisposed to many metabolic dyscrasias, such as insulin resistance, altered blood lipids, and feline hepatic lipidosis. Fibroblast Growth Factor-21 (FGF21) an endocrine hormone that mediates the fat-liver axis, in humans animals, FGF21 can ameliorate non-alcoholic fatty liver disease, obesity. Activation pathway may have therapeutic benefits for obese cats.In this preliminary cross-sectional study, ad libitum...
Hydrogels with polysaccharides as high polymer substrates have surprising advantages in wastewater treatment complex components. Therefore, this study, named EPS were extracted from Enteromorpha prolifera, a coastal pollutant wide range of sources, and cationic modification was performed to obtain CAEPS, the hydrogel double network structure prepared based on CAEPS. Meanwhile, structural characteristic CAEPS-based identified by HPLC, AFM, FT-IR, TGA, SEM-EDS, Pore size distribution, WCA,...
Upgma analysis, principal component genetic diversity analysis and distance of RAPD data were used to assess the extent host specialization in 50 isolates S. homoeocarpa from five turfgrass hosts. In upgma occurrence was not readily apparent based on visual inspection. Genetic showed significant differentiation among different species ( G ST = 0.34, P < 0.001). The strongest evidence for some degree came statistical distances isolates. By grouping pairwise between their species, analysing...
Eimeria spp. are important intestinal pathogens of chickens (Gallus gallus domesticus). Anticoccidial feed additives, chemicals, and ionophores have traditionally been used to control infections in broiler production. Thus, the trend toward antibiotic-free organic production requires new approaches coccidiosis prevention. Two not mutually exclusive methods use plant extracts with antiparasitic activity manipulation microbiota by pre- probiotics. In present study, birds were inoculated a...
Alkali-surfactant-polymer flooding technology is widely employed to extract crude oil enhance its production. The bacterial strain Rhodococcus erythropolis SY095 has shown high degradation activity of alkane oil. In the past, many treatment strategies have been implemented reduce concentration in wastewater. Previous studies mainly focused on extracellular products Erythrococcus rather than properties. current study, we designed an immobilization method modify surface R. with functional...
Ursodeoxycholic acid is an important clinical drug in the treatment of liver disease. In our previous work, ursodeoxycholic was prepared by electroreduction 7-ketolithocholic acid. The separation from product (47% (w/w) acid) silylation crystallization described herein. N,N-dimethylformamide used as solvent, whereas hexamethyldisilazane reaction agent. optimal material ratio product/N,N-dimethylformamide/hexamethyldisilazane found to be 1:10:2 (w/v/v). proceeded for 2 h at 60°C, and...
Abstract Background Fecal specimens are critical for disease screening, diagnosis, and gut microbiome research. For domestic cats, lubricants often necessary to obtain a sufficient quantity of sample. However, the effect lubrication on feline analysis has not been assessed. Objectives To evaluate if using mineral oil during cat feces sample collection affects DNA extraction, metagenomic sequencing yield, microbial composition diversity in subsequent analyses. Animals Eight 6‐year‐old male,...