- Fish Biology and Ecology Studies
- Fish Ecology and Management Studies
- Ichthyology and Marine Biology
- Inertial Sensor and Navigation
- Herpesvirus Infections and Treatments
- Identification and Quantification in Food
- Viral gastroenteritis research and epidemiology
- Fish biology, ecology, and behavior
- Spacecraft Design and Technology
- Marine and fisheries research
- Viral Infections and Vectors
- Virus-based gene therapy research
- Space Satellite Systems and Control
- Aquaculture Nutrition and Growth
- Animal Genetics and Reproduction
- Animal Virus Infections Studies
- SARS-CoV-2 and COVID-19 Research
- Poxvirus research and outbreaks
- Dynamics and Control of Mechanical Systems
- Viral Infections and Outbreaks Research
- Cytomegalovirus and herpesvirus research
- Vector-Borne Animal Diseases
- Adaptive Control of Nonlinear Systems
- Astronomical Observations and Instrumentation
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
National Institute of Infectious Diseases
2021-2025
Okinawa Institute of Science and Technology Graduate University
2015-2024
James Cook University
2024
Sakakibara Hospital
2024
Yamaguchi University
2005-2022
Okayama University of Science
2022
Yamaguchi Prefecture Central Hospital
2022
The University of Tokyo
1992-2020
Okinawa Churashima Foundation
2018
Tokai University
2015
Two new species of Rhinogobius found in streams on central part Palawan Island, Philippines are described. The two species, estrellae and tandikan share unique transverse rows sensory papillae the cheek with similis Gill, 1859, but differ from latter fin ray counts, arrangement scales, etc. distinguished each other by pectoral-fin count, longitudinal- predorsal-scale colouration body. R. have been allopatrically a stream within Malatgao River system flowing into Sulu Sea Cayulo South China...
Mpox virus (MPXV) is a zoonotic orthopoxvirus and caused an outbreak in 2022. Although tecovirimat brincidofovir are approved as anti-smallpox drugs, their effects mpox patients have not been well documented. In this study, by drug repurposing approach, we identified potential candidates for treating predicted clinical impacts mathematical modeling.
Most teleost fishes exhibit a biphasic life history with larval oceanic phase that is transformed into morphologically and physiologically different demersal, benthic, or pelagic juveniles. This process of transformation characterized by myriad hormone-induced changes, during the often abrupt transition between juvenile phases called metamorphosis. Thyroid hormones (TH) are known to be instrumental in triggering coordinating this but other hormonal systems such as corticoids, might also...
In order to locate amino acid residues involved in the formation of feline calicivirus (FCV) neutralizing epitopes, we analysed capsid protein gene monoclonal antibody neutralization-resistant variants FCV. Amino substitutions were identified two hypervariable regions protein. Four linear and conformational epitopes located from 426 460 490 520, respectively. The relative positions individual agreed with our previous antigenic analy- sis.Two sitescomposed mapped protein, demonstrating that a...
Abstract Oz virus is a novel thogotovirus isolated from ticks that causes lethal infection in mice. We conducted serosurveillance of among humans and wild mammals Japan using virus-neutralization tests ELISAs. Results showed may be naturally infecting other mammalian hosts.
In November 2020, a volunteer group reported an outbreak of infectious disease with high fatality rate and flu-like symptoms among stray cats in Aoshima, remote island Ehime, Japan. Nine adult severe were hospitalized. Feline calicivirus (FCV) was isolated from pharyngeal swabs six hospitalized cats. An virulent systemic FCV (VS-FCV) infection initially suspected because obvious cats; however, no typically associated VS-FCV, such as skin ulcers on the limbs, edema, or viremia, observed....
Pancreatic islets from DBA/2 mice infected with the D variant of encephalomyocarditis (EMC-D) virus revealed lymphocytic infiltration moderate to severe destruction pancreatic beta cells. Our previous studies showed that major population infiltrating cells at early stages infection is macrophages. The inactivation macrophages prior viral resulted in prevention diabetes, whereas activation enhancement beta-cell destruction. This investigation was initiated determine whether...
Although raccoons (Procyon lotor) are susceptible to influenza viruses, highly pathogenic avian virus (H5N1) infection in these animals has not been reported. We performed a serosurvey of apparently healthy feral Japan and found specific antibodies subtype H5N1 viruses. Feral may pose risk farms public health.
Authors of the March WHO report into how COVID-19 emerged warn that further delay makes crucial inquiry biologically difficult.
Oz virus (OZV) was isolated from an Amblyomma tick in Japan and shown to cause lethal viral myocarditis humans. However, the natural reservoirs distribution of OZV remain unknown. We describe epidemiologic studies conducted by using serum samples collected mammals throughout Japan. The results showed that 27.5% wild boars, 56.1% Sika deer, 19.6% Japanese macaques, 51.0% Asian black bears were positive for virus-neutralizing antibodies against OZV. Approximately 2.8% dogs 1.0% cats also...
Drifting fish larvae were collected with a plankton net in the lower reaches of freshwater area Teima Stream, Okinawa Island, Japan, during 24 hr periods each month from June 1998 to October 1999 (except July 1998). Newly hatched several gobioid and two pipefish species collected, their morphology was described. The larval occurrences suggested that most spawn mainly spring fall, some Rhinogobius spawning winter. Larvae all fishes occurred predominantly hours after dusk diroughout year. It...
Abstract Sicydiinae species have an amphidromous life cycle during which they undergo a pelagic larval phase allowing them to disperse through the ocean and recruit in distant island rivers. Hypotheses for differences observed dispersal abilities between include variation duration (PLD). However, implication of PLD as proxy explaining ability is not clear subfamily. In this study, otolith microstructure three was analysed. One these species, Sicyopus zosterophorum , has widespread...
Abstract The mosquito, Aedes baisasi , which inhabits brackish mangrove swamps, is known to feed on fish. However, its host assemblage has not been investigated at the species level. We amplified and sequenced cytochrome oxidase subunit I barcoding regions as well some other from blood-fed females identify assemblages in natural populations four islands Ryukyu Archipelago. Hosts were identified 230 females. 15 fish belonging eight families orders. Contrary expectations previous observations,...
This paper examines the temporal and spatial change in characteristics of sea-ice motion Arctic. Ice is generally expressed by a at constant ratio (wind factor) wind speed, with certain angle (turning angle) from direction, ocean currents. study aimed to reveal recent changes factor turning using satellite observation data. We first prepared daily ice-velocity data set for 2003–2017 collected microwave sensor Advanced Microwave Scanning Radiometer Earth Observing System (AMSR-E) its...
Abstract Monkeypox virus (MPXV) is a zoonotic orthopoxvirus that causes smallpox-like symptoms in humans and caused an outbreak May 2022 led the WHO to declare global health emergency. In this study, from screening of approved-drug libraries using MPXV infection cell system, atovaquone, mefloquine, molnupiravir exhibited anti-MPXV activity, with 50% inhibitory concentrations 0.51-5.2 μM, which more potent than cidofovir. Whereas mefloquine was suggested inhibit viral entry, atovaquone...
Abstract Recently, a new paramyxovirus closely related to human mumps virus (MuV) was detected in bats. We generated recombinant MuVs carrying either or both of the fusion and hemagglutinin-neuraminidase bat glycoproteins. These viruses showed replication kinetics similar MuV cultured cells were neutralized efficiently by serum from healthy humans.
Eggs and larvae of three amphidromous species Rhinogobius goby (Rhinogobius brunneus, sp. MO CB) from Okinawa Island, Japan, were reared under uniform conditions to describe compare their larval development. Although the morphologies very similar, some differences observed in timing ontogenetic events among them. R. brunneus had largest yolk saved it for a longer period time, whereas smallest yolk, which was exhausted earlier. The until exhaustion is thought restrict distance that migrating...
ABSTRACT: A woman in her 50s showed symptoms of fever, loss appetite, vomiting, and general fatigue 2 days after she was bitten by a sick cat, which had later died, Yamaguchi prefecture, western Japan, June 2016. She subsequently died multiorgan failure, an autopsy performed to determine the cause death. However, etiological pathogens were not quickly identified. The pathological features patient retrospectively re-examined, pathology regional lymph node at site cat bite found show...
Binary hydroxyl ammonium nitrate (HAN) aqueous mixtures have been prepared. Four series of ternary synthesized with methanol and ethanol as fuels: two HAN excess other stoichiometric fuel contents. Thermal catalytic decomposition the prepared solutions analyzed. For binary solutions, thermal starts only once water has fully vaporized oxidizer is in liquid state. The influence depends strongly on oxidizer. Methanol are before decomposition, leading to results close those observed for...