- Nutritional Studies and Diet
- Phytochemicals and Antioxidant Activities
- Antioxidant Activity and Oxidative Stress
- Consumer Attitudes and Food Labeling
- Diet and metabolism studies
- Horticultural and Viticultural Research
- Fatty Acid Research and Health
- Alcohol Consumption and Health Effects
- Fermentation and Sensory Analysis
- Pomegranate: compositions and health benefits
- Diet, Metabolism, and Disease
- Agricultural and Food Production Studies
- Obesity, Physical Activity, Diet
- Genomics, phytochemicals, and oxidative stress
- Folate and B Vitamins Research
- Culinary Culture and Tourism
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Bacteriophages and microbial interactions
- Vitamin C and Antioxidants Research
- Natural Antidiabetic Agents Studies
- Ginkgo biloba and Cashew Applications
- High Altitude and Hypoxia
- Liver Disease Diagnosis and Treatment
- Food, Nutrition, and Cultural Practices
- Health and Lifestyle Studies
Pontificia Universidad Católica de Chile
2009-2022
University of Chile
2005
The Mediterranean diet is a healthy with positive scientific evidence of preventing chronic diseases. Bioactive components support the properties diet. Antioxidants and fiber, two diet, are key functional nutrients for eating nutrition. Wine grape pomace rich source these dietary constituents may be beneficial human health. Our hypothesis was that intake red wine flour (WGPF) prepared from grapes (Cabernet Sauvignon variety) reduced metabolic syndrome in humans. To evaluate effect WGPF on we...
Abstract Objective To evaluate the feasibility of diet mediterranisation, in a food-at-work context, and its consequence on metabolic syndrome mid-age unselected healthy male population group. Design One-year longitudinal intervention study. Physical exercise was not modified. Setting All workers Santiago division ‘Maestranza Diesel’, metal-mechanic company servicing mining industry, were invited to participate. Subjects Initially, 145 total 171, average age 39 years, accepted participate...
Irarrázaval, Sebastián, Claudio Allard, Juan Campodónico, Druso Pérez, Pablo Strobel, Luis Vásquez, Inés Urquiaga, Guadalupe Echeverría, and Federico Leighton. Oxidative stress in acute hypobaric hypoxia. High Alt Med Biol. 18:128-134, 2017.-The effects of hypoxia endured by mountaineers were studied, specifically as evidenced mountain sickness (AMS) oxidative damage. Ten male volunteers exposed to hypoxia, AMS was evaluated through arterial oxygen saturation (SaO2), cardiac rate, the Lake...
A bstract : Oxidative stress is a central mechanism for the pathogenesis of ischemic heart disease and atherogenesis, cancer other chronic diseases in general, it also plays major role aging process. Dietary antioxidants constitute large group compounds that differ action, bioavailability side effects. systematic analysis various hampered by difficulty employing death or clinical events as end points intervention studies. Therefore, valid markers oxidative stress, which show dose response...
Background and Aims . Hyperferritinemia has been related with a wide spectrum of pathologies, including diabetes, cardiovascular disease, neurodegenerative disorders, metabolic syndrome. The aim this study was to investigate the association between hyperferritinemia iron consumption. Methods Results Serum ferritin concentration evaluated in 66 presumed healthy men, along other clinical biochemical markers chronic diseases. A three-day food questionnaire applied for nutrition information....
Obesity and metabolic syndrome (MetS) are key risk factors for chronic disease. Dietary patterns critical in the incidence persistence of obesity MetS, yet there is few data linking diet to MetS Chile. Our objective was use a locally validated index evaluate adherence Mediterranean dietary pattern its correlations with overweight/obesity (OW/O) prevalence Chilean adults. We conducted nationwide, cross-sectional online survey adults complete self-reported body mass (n = 24,882). A subsample...
Wine grape pomace flour (WGPF) is a fruit byproduct that high in fiber and antioxidants. We tested whether WGPF consumption could affect blood biochemical parameters, including oxidative stress biomarkers. In three-month intervention study, 27 male volunteers, each with some components of metabolic syndrome, consumed beef burger supplemented 7% containing 3.5% 1.2 mg gallic equivalents (GE)/g polyphenols (WGPF-burger), daily, during the first month. The volunteers no burgers second month,...
A healthy dietary pattern and high quality nutrient intake reduce atherosclerotic cardiovascular disease risk. Red wine grape pomace (RWGP)—a rich natural source of fiber antioxidants—appears to be a potential functional food ingredient. The impact supplementation with RWGP flour was evaluated in atherogenic diet-fed SR-B1 KO/ApoER61h/h mice, model lethal ischemic heart disease. mice were fed (high fat, cholesterol, cholic acid, HFC) diet supplemented with: (a) 20% chow (HFC-Control), (b)...
This study formulated and characterized an antioxidant‐rich concentrate of berries (BPC‐350) produced in Chile, which was used to perform a crossover aimed at determining the effect on modulation plasma postprandial oxidative stress antioxidant status. Healthy male volunteers ( N = 11) were randomly assigned three experimental meals: (1) 250 g ground turkey burger (GTB) + 500 mL water; (2) GTB 5% BPC‐350; (3) prepared with 6% BPC‐350 BPC‐350. Venous blood samples collected prior meal intake...
Validation of self-applicable questionnaire for a Mediterranean dietary index in ChileBackground: Availability brief indexes that can effectively evaluate patterns and their association with health is critical prevention management several chronic disease conditions.Aim: To adapt Dietary Index Chile (Chilean-MDI).Material Methods: The Chilean-MDI was developed based on previous eating score adapted to Chilean habits.This further validated sample 153 adults by comparing the concordance...
The type of diet consumed by individuals has been associated with the development some chronic diseases, including cardiovascular disease (CVD), cancer, diabetes, and others.Populations that consume diets rich in fruits vegetables drink wine moderation, as Mediterranean, have a higher life expectancy less diseases than other occidental populations.We carried out an intervention study humans to evaluate effect Mediterranean (MD), Occidental (OD) their supplementation red wine, on biochemical,...
Metabolic syndrome is a growing worldwide health problem. We evaluated the effects of wine grape powder (WGP), rich in antioxidants and fiber, rat model metabolic induced by high fructose diet. tested whether WGP supplementation may prevent glucose intolerance decrease oxidative stress rats fed with Male Sprague-Dawley weighing 180 g were divided into four groups according to their feeding protocols. Rats control diet (C), plus 20 % (C + WGP), 50 (HF) or (HF WGP) for 16 weeks. Blood glucose,...
Context Grape pomace maybe useful in broiler diets as a source of low cost antioxidants. Aims The objective this work was to determine the effect including high concentrations wine-grape flour (WGPF) chicken on productive parameters and antioxidant capacity meat. Methods WGPF white (WGPF-W) red (WGPF-R) grape varieties were nutritionally chemically characterised. Then, 120 chickens allocated three isoenergetic isoproteic feeding treatments: 0% (Control), 20% WGPF-W WGPF-R. Key results had no...
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