- Nutritional Studies and Diet
- Obesity, Physical Activity, Diet
- Consumer Attitudes and Food Labeling
- Diet and metabolism studies
- Health and Lifestyle Studies
- Antioxidant Activity and Oxidative Stress
- Birth, Development, and Health
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Phytochemicals and Antioxidant Activities
- Lipoproteins and Cardiovascular Health
- Healthcare professionals’ stress and burnout
- Stress and Burnout Research
- Agricultural and Food Production Studies
- Psychological Well-being and Life Satisfaction
- Nutrition, Genetics, and Disease
- Folate and B Vitamins Research
- Physical Activity and Health
- Cardiac Health and Mental Health
- Diet, Metabolism, and Disease
- Sphingolipid Metabolism and Signaling
- Male Reproductive Health Studies
- Vitamin C and Antioxidants Research
- Health, psychology, and well-being
- Food, Nutrition, and Cultural Practices
- Reproductive Health and Technologies
Pontificia Universidad Católica de Chile
2016-2025
Sociedad Española de Endocrinología y Nutrición
2023
Dominican University
2019
University of Chile
2011-2015
Fundación Chile
2011
The Mediterranean diet is a healthy with positive scientific evidence of preventing chronic diseases. Bioactive components support the properties diet. Antioxidants and fiber, two diet, are key functional nutrients for eating nutrition. Wine grape pomace rich source these dietary constituents may be beneficial human health. Our hypothesis was that intake red wine flour (WGPF) prepared from grapes (Cabernet Sauvignon variety) reduced metabolic syndrome in humans. To evaluate effect WGPF on we...
Abstract Objective To evaluate the feasibility of diet mediterranisation, in a food-at-work context, and its consequence on metabolic syndrome mid-age unselected healthy male population group. Design One-year longitudinal intervention study. Physical exercise was not modified. Setting All workers Santiago division ‘Maestranza Diesel’, metal-mechanic company servicing mining industry, were invited to participate. Subjects Initially, 145 total 171, average age 39 years, accepted participate...
The Mental Health Continuum-Short Form (MHC-SF) is a multidimensional measure of well-being designed to assess emotional, psychological and social well-being. It has been translated into different languages; however, there no validated Spanish version. Our aim was provide the Spanish-speaking community with version MHC-SF.We questionnaire (s-MHC-SF) assessed its validity in sample 3,355 Chilean adults. data subjected confirmatory factor analysis using original correlated-traits three-factor...
Irarrázaval, Sebastián, Claudio Allard, Juan Campodónico, Druso Pérez, Pablo Strobel, Luis Vásquez, Inés Urquiaga, Guadalupe Echeverría, and Federico Leighton. Oxidative stress in acute hypobaric hypoxia. High Alt Med Biol. 18:128-134, 2017.-The effects of hypoxia endured by mountaineers were studied, specifically as evidenced mountain sickness (AMS) oxidative damage. Ten male volunteers exposed to hypoxia, AMS was evaluated through arterial oxygen saturation (SaO2), cardiac rate, the Lake...
Background and Aims . Hyperferritinemia has been related with a wide spectrum of pathologies, including diabetes, cardiovascular disease, neurodegenerative disorders, metabolic syndrome. The aim this study was to investigate the association between hyperferritinemia iron consumption. Methods Results Serum ferritin concentration evaluated in 66 presumed healthy men, along other clinical biochemical markers chronic diseases. A three-day food questionnaire applied for nutrition information....
Obesity and metabolic syndrome (MetS) are key risk factors for chronic disease. Dietary patterns critical in the incidence persistence of obesity MetS, yet there is few data linking diet to MetS Chile. Our objective was use a locally validated index evaluate adherence Mediterranean dietary pattern its correlations with overweight/obesity (OW/O) prevalence Chilean adults. We conducted nationwide, cross-sectional online survey adults complete self-reported body mass (n = 24,882). A subsample...
Wine grape pomace flour (WGPF) is a fruit byproduct that high in fiber and antioxidants. We tested whether WGPF consumption could affect blood biochemical parameters, including oxidative stress biomarkers. In three-month intervention study, 27 male volunteers, each with some components of metabolic syndrome, consumed beef burger supplemented 7% containing 3.5% 1.2 mg gallic equivalents (GE)/g polyphenols (WGPF-burger), daily, during the first month. The volunteers no burgers second month,...
A healthy dietary pattern and high quality nutrient intake reduce atherosclerotic cardiovascular disease risk. Red wine grape pomace (RWGP)—a rich natural source of fiber antioxidants—appears to be a potential functional food ingredient. The impact supplementation with RWGP flour was evaluated in atherogenic diet-fed SR-B1 KO/ApoER61h/h mice, model lethal ischemic heart disease. mice were fed (high fat, cholesterol, cholic acid, HFC) diet supplemented with: (a) 20% chow (HFC-Control), (b)...
Abstract Background The COVID-19 pandemic has had an impact not only on healthcare but also labor and socioeconomic sectors worldwide, leading to the development of strategies mitigate crisis’ widespread repercussions. In Antofagasta, Chile, innovation project entitled Volvamos Juntos (“ Let’s Return Together” ) was developed support a diverse group micro small businesses. consisted accompanying companies in process reopening safely included interventions ranging from educating testing...
This study formulated and characterized an antioxidant‐rich concentrate of berries (BPC‐350) produced in Chile, which was used to perform a crossover aimed at determining the effect on modulation plasma postprandial oxidative stress antioxidant status. Healthy male volunteers ( N = 11) were randomly assigned three experimental meals: (1) 250 g ground turkey burger (GTB) + 500 mL water; (2) GTB 5% BPC‐350; (3) prepared with 6% BPC‐350 BPC‐350. Venous blood samples collected prior meal intake...
After enforcement of a new food labeling law in 2016, Chile exhibits greater offer to reduced sugar products with addition non-nutritive sweeteners (NNS). Many these are consumed by children, who at risk reaching the acceptable daily intake (ADI) additives. The objective this study was evaluate levels NNS Chilean schoolchildren after enactment aforementioned law. A total 250 children 6–12 years old were surveyed. assessed through frequency questionnaire. All evaluated least one during...
Validation of self-applicable questionnaire for a Mediterranean dietary index in ChileBackground: Availability brief indexes that can effectively evaluate patterns and their association with health is critical prevention management several chronic disease conditions.Aim: To adapt Dietary Index Chile (Chilean-MDI).Material Methods: The Chilean-MDI was developed based on previous eating score adapted to Chilean habits.This further validated sample 153 adults by comparing the concordance...
The burnout syndrome affects more than half of students and professionals involved in healthcare worldwide is characterized by emotional exhaustion, depersonalization a low perception self-efficacy. Several studies indicate that when are burnt-out, clinical work, professionalism ethical behavior, as well empathy, negatively affected, while the risk academic attrition, depression suicidal ideation tend to increase. At national level, recent information shows one out every two medical suffer...
Medical students experience high levels of psychological stress during clinical training. However, most medical curricula do not teach self-care skills. The COVID-19 pandemic has disrupted education causing increased distress among students.To report the implementation and impact an eight-week multifaceted mindfulness-based program on students' well-being pandemic.One hundred twenty-three fourth-year attended as part a mandatory course from April to May 2020, rising phase in Chile. They were...
SR-BI is the main receptor for high density lipoproteins (HDL) and mediates bidirectional transport of lipids, such as cholesterol vitamin E, between these particles cells. During early development, expressed in extraembryonic tissue, specifically trophoblast giant cells parietal yolk sac. We previously showed that approximately 50% SR-BI-/- embryos fail to close anterior neural tube develop exencephaly, a perinatal lethal condition. Here, we evaluated role embryonic E uptake during murine...
Active travel such as walking or cycling has been associated with more favorable health outcomes. However, evidence on patterns of transportation in Latin America is scarce. Therefore, the aim this study was to quantify and characterise socio-demographic public, private active American countries. Data from Study Nutrition Health, a population-based, cross-sectional survey conducted eight countries including Argentina, Brazil, Chile, Colombia, Costa Rica, Ecuador, Peru Venezuela (n = 9218;...
High-density lipoprotein (HDL) plays a critical role in protection against atherosclerosic and cardiovascular disease (ASCVD). In addition to contributing clearing excess vascular cholesterol, HDL particles exhibit antioxidative functions, helping attenuate adverse effects of oxidized low-density lipoproteins. However, these beneficial properties can be undermined by oxidative stress, inflammation, unhealthy lifestyles diet, as well influenced race sex. Thus, when assessing risk, it is...
Most worldwide causes of disease and death are strongly associated with dietary factors the application eating indexes has proved to be a useful tool determine diet quality in populations. The aim this study was evaluate Chile through Alternate Healthy Eating Index 2010 (AHEI-2010). A representative sample (n = 879) Chilean urban population aged 15⁻65 years old from Latin American Study Nutrition Health (Estudio Latinoamericano de Nutrición y Salud; ELANS) used. Dietary intake data were...
Abstract Emerging research has linked psychological well-being with many physiological markers as well morbidity and mortality. In this analysis, the relationship between components of eudaimonic serum sphingolipids levels was investigated using data from a large national survey middle-aged American adults (Midlife in United States). Health behaviors (i.e., diet, exercise, sleep) were also examined potential mediators these relationships. Serum total ceramides—the main molecular class...